[HN Gopher] Nanoparticle sensor can distinguish between viral an...
       ___________________________________________________________________
        
       Nanoparticle sensor can distinguish between viral and bacterial
       pneumonia
        
       Author : gmays
       Score  : 62 points
       Date   : 2022-06-15 14:10 UTC (1 days ago)
        
 (HTM) web link (news.mit.edu)
 (TXT) w3m dump (news.mit.edu)
        
       | hirenj wrote:
       | Host protease activity classifies pneumonia etiology. Anahar et
       | al. (2022), PNAS
       | 
       | https://www.pnas.org/doi/10.1073/pnas.2121778119
        
         | hirenj wrote:
         | So what they've got is a bunch of barcoded synthetic peptides,
         | which they use to assay for protease activity (is there even
         | enough specificity information for each protease?). Based on
         | the signature of activity they fit some model to tell one
         | infection apart from the other.
         | 
         | It's a neat application of their technology (basically barcoded
         | peptides), and I would imagine this reflects tropism of viruses
         | and bacteria, and the different inflammatory responses likely
         | elucidated by the respective cells being damaged.
        
       | foxhop wrote:
       | are they suggesting inhalation of nanoparticles sensors? or is
       | the sample a swab going into a device?
        
         | ojuikty wrote:
         | It uses urine samples. This has only been validated in an
         | animal model.
        
       ___________________________________________________________________
       (page generated 2022-06-16 23:01 UTC)