[HN Gopher] Are toxoplasma-infected subjects more attractive tha...
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       Are toxoplasma-infected subjects more attractive than non-infected
       ones?
        
       Author : kloch
       Score  : 75 points
       Date   : 2022-04-02 15:50 UTC (7 hours ago)
        
 (HTM) web link (peerj.com)
 (TXT) w3m dump (peerj.com)
        
       | michalrichards9 wrote:
       | The statistics in this paper are... not robust IMHO. They do so
       | many comparisons between the groups and never mention any
       | multiple comparisons correction.
       | 
       | Interesting idea, I am not convinced right now - but let's see if
       | it reproduces.
        
         | lupire wrote:
         | It may be more likely to reproduce if it gets infected with
         | toxoplasma.
        
           | Quixotica1 wrote:
           | Well said, lol
        
       | lupire wrote:
       | Even _suggesting_ that facial assymetry in adults, which takes
       | decades to develop, is reduced by a parasite, is an extremely
       | extraordinary claim, that requires far more evidence than this.
       | 
       | What plausible mechanism is there for the body to even detect
       | asymmetry and then change it? Your brain can't make your ear move
       | lower.
        
       | mrfusion wrote:
       | Toxoplasma are kinda like the Gould. Can they help us heal too?
        
         | rdevsrex wrote:
         | I believe it's spelled Goa'uld :) Who knows, but the very fact
         | that a parasite can co-opt our sense of smell to make cat urine
         | smell not as bad, is saying something.
        
           | ben_w wrote:
           | I also assume that's what mrfusion meant, but there is also
           | Sabine Baring-Gould who wrote (among other works) "The Book
           | of Were-Wolves", which is clearly relevant to the topic of
           | mysterious healing powers:
           | 
           | https://en.m.wikisource.org/wiki/The_Book_of_Were-Wolves
        
       | marcodiego wrote:
       | "we found that infected men had lower facial fluctuating
       | asymmetry whereas infected women had lower body mass, lower body
       | mass index, a tendency for lower facial fluctuating asymmetry,
       | higher self-perceived attractiveness, and a higher number of
       | sexual partners than non-infected ones. Then, we found that
       | infected men and women were rated as more attractive and
       | healthier than non-infected ones."
        
       | freddealmeida wrote:
       | It is clear that parasites do change our genome and how we
       | express our genes in order to further transmit themselves. It
       | would not be surprising that good looks, lower body fat, etc
       | increases sexual contact and therefor transmission.
       | 
       | New sexual strategies are need I suppose.
        
       | nootropicat wrote:
       | >t. toxoplasma gondii
        
       | dsign wrote:
       | Well, I for one believe and amuse myself with the findings of
       | this paper. It reminds us that nature is not a divinity of
       | perfection working in our favor (if anybody had any doubt at this
       | point, that is).
        
       | [deleted]
        
       | kwatsonafter wrote:
       | Man that's some fucked up shit. I'd bet you'll see Kardash-clone
       | ladies putting catshit flakes on their cereal to get, "lean'd." I
       | think it's important to note the apostrophe, "d."
        
       | auntienomen wrote:
       | Of course they are! They have a kitty!
        
         | tornato7 wrote:
         | So people with cats are happier and take better care of
         | themselves
        
       | collegeburner wrote:
       | Don't let the incels get ahold of this, they'll be eating cat
       | poop by the bucketful.
        
       | pengaru wrote:
       | Isn't it already understood that toxoplasmosis increases risk-
       | taking behavior?
       | 
       | More sexual mates is riskier, living athletic/outdoorsy/"active"
       | lives is also more risky than being a couch potato...
       | 
       | I don't think we're breaking new ground in saying the risk-averse
       | tend to be less sexually attractive.
        
       | adhesive_wombat wrote:
       | First we had Botox, but how long until you can have Toxtox and
       | have someone inject protozoa into your face in their living room?
        
       | abeppu wrote:
       | From a quick skim, it looks like they don't present anything
       | which would distinguish which way the causal arrow points. Do the
       | parasites make their hosts more attractive so they are more
       | likely to be passed on, or do more attractive people have more
       | sex that gives them opportunities to be infected?
        
         | layer8 wrote:
         | Or maybe the more attractive people are just more attractive to
         | T. Gondii.
        
         | holub008 wrote:
         | Seriously, has the bar sunk this low? I was certain the authors
         | would express caution in interpreting causality, but alas: "Our
         | results suggest that some sexually transmitted parasites, such
         | as T. gondii, may produce changes in the appearance and
         | behavior of the human host".
        
           | folli wrote:
           | T. gondii is not a sexually transmitted parasite. Or am I
           | missing something?
        
             | holub008 wrote:
             | I was directly quoting the article and am not a domain
             | expert. It is interesting to see some commenters here state
             | that it isn't an STD. It appears this is an open question.
             | 
             | https://academic.oup.com/aje/article/190/3/386/5905708
             | https://pubmed.ncbi.nlm.nih.gov/24986706/
        
           | lupire wrote:
           | > may
           | 
           | That _is_ expressing caution.
        
             | holub008 wrote:
             | Perhaps it's because I don't frequent the literature, but I
             | interpret that as "T Gondii. may [provided by our level of
             | statistical certainty in MANCOVA] produce changes".
             | Otherwise, what's the point of performing a statistical
             | analysis? Moreover what's the value of any assertion if it
             | can be guarded by an unbounded-uncertainty keyword "may".
        
               | ascar wrote:
               | I think that's a classic case of reading between the
               | lines and making implications where one shouldn't. If I'm
               | using words that state uncertainty, it is because I am
               | not certain, but only say it is a possibility. A research
               | result that shows there is a correlation is already
               | interesting without establishing or confirming causation.
               | Their wording is exactly saying that. Without that paper
               | we wouldn't even know there is a correlation!
               | 
               | How else would you like them to state that without being
               | overly verbose?
        
               | holub008 wrote:
               | > How else would you like them to state that without
               | being overly verbose?
               | 
               | "Our results suggest that some sexually transmitted
               | parasites, such as T. gondii, may be correlated with
               | appearance and behavior of the human host."
               | 
               | I appreciate your viewpoint. I would counter it by saying
               | that there are two sources of uncertainty here: choice of
               | model & sampling variance. It's my opinion that in
               | scientific writing, one should be precise with which
               | source of uncertainty they are guarding. If I'm allowed
               | to group these together, why can't I make a similar
               | statement of causation of any old spurious correlation -
               | when obviously my model is bad?
               | 
               | Considering this example again - isn't it arbitrary that
               | the authors get to choose which hypothesis (among many,
               | like attractive people being predisposed to own cats)
               | they get to claim "may" be demonstrated?
               | 
               | Similar line of discussion: https://statmodeling.stat.col
               | umbia.edu/2015/04/04/thinking-p...
        
               | ascar wrote:
               | > "Our results suggest that some sexually transmitted
               | parasites, such as T. gondii, may be correlated with
               | appearance and behavior of the human host."
               | 
               | But that is a different statement. They say that they
               | found correlation and there may be causation. You say
               | there may be correlation, a much weaker claim.
               | 
               | > Considering this example again - isn't it arbitrary
               | that the authors get to choose which hypothesis (among
               | many, like attractive people being predisposed to own
               | cats) they get to claim "may" be demonstrated?
               | 
               | Of course it is arbitrary. But that was their hypothesis
               | and you have to start with some hypothesis, no? They
               | gathered data to establish correlation between the
               | infection and attractiveness. They didn't gather data for
               | anything else, so I think it's pretty reasonable to say
               | we found correlation and further research might be
               | interesting to see if there is causation.
               | 
               | Literally the next sentence says "Taken together, these
               | results lay the foundation for future research".
               | 
               | If you go beyond the abstract and into the actual
               | article, they are pretty careful to just list
               | possibilities for the observed correlation. They
               | certainly could have stated that it might just be
               | spurious correlation there, but I don't blame them too
               | much. These articles are supposed to be concise and not
               | verbose and especially the abstract is supposed to be as
               | concise and short as possible.
               | 
               | I agree with your general premise and the linked article
               | though. It should be a given to consider that and ideally
               | also state it in the article.
        
         | axlee wrote:
         | > Do the parasites make their hosts more attractive so they are
         | more likely to be passed on, or do more attractive people have
         | more sex that gives them opportunities to be infected?
         | 
         | T. Gondii reproduces in felines, and is transmitted initially
         | through their feces to other hosts. Humans catch it most often
         | through infected food (meat, vegetables) or liquids (water,
         | milk). Humans cannot transmit T. Gondii to other humans, unless
         | pregnancies, organ transplants or cannibalism are involved.
         | 
         | So, regardless of how attractive an host is, he won't have more
         | or less opportunities to be infected with T. Gondii than anyone
         | else. This is not a STD.
         | 
         | Unless there is some sort of correlation between attractiveness
         | and eating poorly corked meat.
        
           | abeppu wrote:
           | I think the point of the article disagrees with you? Like, to
           | my reading, the hypothesis is that T. Gondii should be under
           | selective pressure to support its host mating, because that
           | aids its spread.
           | 
           | From the background paragraph:
           | 
           | > However, if parasites diminish a host's health and
           | attractiveness to such an extent that finding a mate becomes
           | almost impossible, the parasite would decrease its odds of
           | reproducing and passing to the next generation. There is
           | evidence that Toxoplasma gondii (T. gondii) manipulates
           | phenotypic characteristics of its intermediate hosts to
           | increase its spread.
           | 
           | And the conclusions paragraph:
           | 
           | > Our results suggest that some sexually transmitted
           | parasites, such as T. gondii, may produce changes in the
           | appearance and behavior of the human host, either as a by-
           | product of the infection or as the result of the manipulation
           | of the parasite to increase its spread to new hosts. Taken
           | together, these results lay the foundation for future
           | research on the manipulation of the human host by sexually
           | transmitted pathogens and parasites.
           | 
           | It's hard to read that as anything other than the authors
           | classifiying T. gondii as a "sexually transmitted parasite".
           | 
           | I don't know how to reconcile that with what you're saying.
           | Am I missing something?
        
           | wzdd wrote:
           | Contrary to what you wrote about T. gondii definitively not
           | being sexually transmitted between humans, the article links
           | to several studies which postulate exactly that. The
           | paragraph is:
           | 
           | > Since reports that T. gondii can be a sexually transmitted
           | parasite in humans are relatively recent (e.g., Flegr,
           | Klapilova & Kankova, 2014; Hlavacova et al., 2020; Kankova,
           | Hlavacova & Flegr, 2020; Tong et al., 2021), many questions
           | and hypotheses still need to be properly formulated and
           | tested in further studies.
           | 
           | The basis for this theory is that T. gondii cysts have been
           | found in human ejaculate, which means it could for example be
           | transmitted through oral sex. There does not appear to be any
           | conclusive proof that this has happened, but apparently these
           | are viable cysts which, if swallowed in any other context,
           | would result in infection, so it's plausible.
           | 
           | This non-"pregnancies, organ transplants or cannibalism"
           | route is the basis for a lot of this article's theorising
           | about T. gondii benefiting from raising its host's likelihood
           | of having sex.
        
           | dtgriscom wrote:
           | > Humans cannot transmit T. Gondii to other humans, unless
           | pregnancies
           | 
           | (phew.. I'm male)
           | 
           | > organ transplants
           | 
           | (none needed yet)
           | 
           | > or cannibalism are involved.
           | 
           | (oh, NO!!!!!)
        
           | holub008 wrote:
           | How about correlation between attractiveness and owning cats?
           | Attractiveness and having a larger number of partners, which
           | increases odds of exposure to cats / T. Gondii? These
           | hypotheses seem plausible enough that I believe the authors
           | are wrong in claiming causality.
        
             | hunterb123 wrote:
             | Unless people are hooking up in barns I don't think
             | frequenting partners that own cats would be correlated.
             | House cats generally eat kibble, not infected mice.
             | 
             | Even then you'd have to infect yourself with the cat while
             | getting together, as humans don't transfer to each other.
             | 
             | Personally I don't think there's any causation here at all
             | with attractiveness directly.
             | 
             | It may be correlated with more outdoorsy people, those
             | people are probably more attractive on average.
        
               | eurasiantiger wrote:
               | Just want to note that kibble is not the best of foods
               | for cats, especially not as the only food: it tends to
               | cause urinary blockages which are a veterinary emergency.
        
               | holub008 wrote:
               | I wasn't implying infection was occurring during sex, but
               | rather by being in the environment (many people stay
               | around partners for more than sex).
        
               | hunterb123 wrote:
               | I wasn't implying that either, indicated by "as humans
               | don't transfer to each other."
               | 
               | I painted a scenario where your environment would occur,
               | and dispute it by saying those cats in that environment
               | generally aren't infected
               | 
               | Unless those attractive people are hanging out in barns
               | or patios with outside cats.
               | 
               | Now that could be the case if you go at it from an
               | outdoors perspective, outdoorsy people may be more
               | attractive on average, and they may encounter infected
               | cats more on average.
        
               | mulmen wrote:
               | There are house cats all over my neighborhood. I can
               | think of four in the area. It's extremely common to have
               | an outdoor cat as a pet.
               | 
               | Your characterization of cat ownership is unrealistic.
        
               | hunterb123 wrote:
               | Most cat owners I know have inside only cats, as do I. I
               | do know of 3 cats that roam my neighborhood, they could
               | be from quite far away as outdoor cats have a large
               | range.
               | 
               | I guess anecdotes from you or I isn't really telling if
               | an indoor or outdoor majority of cat ownership is
               | "unrealistic". Maybe we need a study :p
               | 
               | Do outside cat owners generally let their cats inside
               | their home?
        
               | mulmen wrote:
               | Doesn't matter, they're domestic cats and you already
               | explained a circumstance where they could expose visitors
               | and owners. Half the year here is a hospitable climate
               | for outdoor recreation and cat survival. Half of it
               | isn't. I have seen these cats for multiple years so
               | unless they have an outdoor cat house (something I have
               | never seen in my life) then I suspect they come inside.
               | 
               | The ratio of cat owners with outdoor cats is irrelevant.
               | They exist and they are common. That's enough to sink
               | your assertions.
        
               | hunterb123 wrote:
               | > Doesn't matter, they're domestic cats and you already
               | explained a circumstance where they could expose visitors
               | and owners
               | 
               | > The ratio of cat owners with outdoor cats is
               | irrelevant.
               | 
               | It's extremely relevant when talking about a large enough
               | scale of infection to support the attractiveness
               | causation hypothesis posed by GP.
               | 
               | > I have seen these cats for multiple years so unless
               | they have an outdoor cat house (something I have never
               | seen in my life)
               | 
               | Outdoor cats generally stay underneath the house /
               | porches, cars, etc. during cold or especially hot
               | weather.
               | 
               | > That's enough to sink your assertions.
               | 
               | I'm disputing the above proposed hypothesis on the
               | grounds I don't think it's common enough occurrence and
               | we're lacking information.
        
               | jjj123 wrote:
               | I don't understand why you keep mentioning hooking up,
               | that seems irrelevant since it's been clarified this is
               | not an STD. The parent comment was saying people who own
               | cats could be more attractive on average, and people who
               | own cats are more likely to get toxoplasmosis.
        
               | hunterb123 wrote:
               | > Attractiveness and having a larger number of partners,
               | which increases odds of exposure to cats
               | 
               | Hooking up was simply an example of why the person would
               | be at the other person's environment.
               | 
               | Replace it with getting together if you're getting hung
               | up on it. Whether or not the humans met up to have sex,
               | talk, stand on their head, or whatever is irrelevant.
               | 
               | The point was house cats generally don't eat infected
               | mice, if you're hanging out in barns or on the patio with
               | outside cats, sure maybe.
        
         | atty wrote:
         | Agreed. I think it's far more likely that the lifestyle
         | differences between more and less attractive individuals is
         | causing increased exposure. Not to mention they performed a LOT
         | of tests without correcting for multiple comparisons (as far as
         | I could tell by skimming). Overall pretty disappointing.
        
       | riccardopa wrote:
       | N=35,178. Give us a break, its too small of a study to make any
       | conclusion.
        
         | jsnodlin wrote:
        
         | tokai wrote:
         | Jokes on you, nothing is concluded.
         | 
         | "Our results suggest [...] these results lay the foundation for
         | future research"
         | 
         | Its the classic do an easy little study, and suggest that the
         | potential for _results_ might point to further studies. Now you
         | have something to tell your research coordinator next time they
         | get in your hair.
        
           | hombre_fatal wrote:
           | We should just have an HN bot that posts these comments if
           | N<1000 or paper.includes(/rats|mice/) for people to upvote.
        
             | carabiner wrote:
             | Wait until HNers find out that n = 10 can be more
             | significant than n = 100 via power analysis.
        
         | hex4def6 wrote:
         | Are toxoplasma-infected scientists more likely to shill for Big
         | Toxoplasma?
        
         | bee_rider wrote:
         | Note that the 35,178 in this comment is actually a list, aka in
         | python: [35, 178], and not the number 35,178 -- which would of
         | course be a large enough sample size to make some observations.
        
         | mrfusion wrote:
         | /s?
        
           | _nhynes wrote:
           | 35 infected, 178 uninfected. The comma is misleading. A slash
           | or semicolon might be better.
        
             | netizen-936824 wrote:
             | Its more than misleading
             | 
             | There's no space after the comma and the commenter is
             | putting two values in a single variable which normal holds
             | an integer
        
       | [deleted]
        
       | callesgg wrote:
       | Being infected with toxoplasma is know to increase reckless
       | behaviour. Having sex with lots of people can be seen as reckless
       | behaviour. Using that argument the conclusion is somewhat
       | reasonable.
       | 
       | Another one I have thought about is HPV virus(or other sexualy
       | transmitted illnesses) and your desire to have sex. There should
       | be a strong evolutionary pressure for the virus to increase your
       | sex drive. If it does, I don't know.
        
         | sometimeshuman wrote:
         | Recklessness in men, is, by its very nature, sexy[0]. Whether
         | toxoplasma became genetically lucky (i.e., trait that is
         | immediately genetically stable after a few mutations) or if
         | evolutionary pressure created this effect (i.e., many
         | generations where this trait grows over time) may be impossible
         | to ever know.
         | 
         | Edit: Downvotes, again? Added a reference. A scientific claim
         | about evolutionary psychology can have merit even if it doesn't
         | fit your personal hopes for the human race. Furthermore, in
         | what world do the downvoters live where women are more likely
         | to causally sleep with the cautious inconspicuous male vs the
         | reckless bad-boy.
         | 
         | [0] https://www.thetimes.co.uk/article/reckless-men-are-more-
         | lik...
        
           | pessimizer wrote:
           | The referenced study is weird[0]. It uses smoking and
           | drinking as a proxy for recklessness in men, but doesn't seem
           | to take into account at all whether the women who were
           | evaluating the men smoked or drank themselves. It's like it
           | forgot it was specifically about smoking and drinking, not
           | recklessness.
           | 
           | Smoking and drinking women young women (<30) would
           | intuitively find smoking and drinking men more attractive for
           | a short term thing, and find that behavior less acceptable
           | for the long term as they probably find it less acceptable
           | for _themselves_ in the long term. Somebody else did this
           | analysis with smokers, but didn 't treat the women as
           | fungible[1]. They found the heightened attraction to smokers
           | _was limited to smokers._
           | 
           | IMO, we don't really need explanation for why reckless (i.e.
           | brave, risky decisionmaking) people have more short-term
           | relationships. They're more willing to proposition people
           | (brave), and more willing to sleep with people who they will
           | ultimately decide they actually don't like (risky
           | decisionmaking.) This is by definition, as valid if not more
           | than the use smoking and drinking as a definitive sign or
           | recklessness.
           | 
           | I'm not saying that people who smoke and drink are more
           | likely to make brave and risky decisions when it comes to
           | interactions with potential sexual partners, but both sets of
           | behaviors can be called "reckless."
           | 
           | > in what world [are] women are more likely to causally sleep
           | with the cautious inconspicuous male vs the reckless bad-boy.
           | 
           | The world in which the cautious inconspicuous male approached
           | her, and the reckless bad boy didn't. Reckless behavior in
           | women is also attractive, but it isn't due to conforming to
           | some chad stereotype; it's due to the fact that if a woman
           | makes bad decisions, sleeping with you might be one of them.
           | 
           | [0] https://journals.sagepub.com/doi/full/10.1177/14747049166
           | 316...
           | 
           | [1] https://www.researchgate.net/publication/263849372_Can_ci
           | gar...
        
           | callesgg wrote:
           | Well, you wrote by its very nature.
           | 
           | For something to be of its very nature it has to be part of
           | that thing.
           | 
           | No reference in the world can make one thing in to another.
        
       | stuckinhell wrote:
       | https://www.smithsonianmag.com/science-nature/the-parasite-t...
       | 
       | This parasite alters sexual behavior in rats, could this be
       | altering people's behavior not just their appearance as well?!
        
         | lupire wrote:
         | Yes, that's _why_ the OP study was done. Toxoplasma has long
         | been theorized to be a factor in  "cat lady" stereotypical
         | behavior.
        
           | collegeburner wrote:
           | Cat lady stereotype runs the other way in attractiveness,
           | counter to the hypothesis formulation.
        
             | lupire wrote:
             | OP study is about facial physical attractiveness, not
             | lifestyle attractiveness.
        
       | xbar wrote:
       | My anecdotal experience is contrary to the science.
        
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