[HN Gopher] These are real compounds
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       These are real compounds
        
       Author : _Microft
       Score  : 114 points
       Date   : 2022-03-23 17:59 UTC (5 hours ago)
        
 (HTM) web link (www.science.org)
 (TXT) w3m dump (www.science.org)
        
       | moron4hire wrote:
       | Always love a good Derek Lowe article. His article "Things I
       | Won't Work With: Dioxygen Diflouride" is terrifying and hilarious
       | at the same time. https://www.science.org/content/blog-
       | post/things-i-won-t-wor...
        
         | malux85 wrote:
         | That was excellent, it just kept building!
        
         | thehappypm wrote:
         | His face is one I started noticing! He seems to have written
         | tons of articles I really enjoyed
        
           | moron4hire wrote:
           | It's not my space, so I don't often read his articles or
           | necessarily recognize his name when it comes up. For me it's
           | the writing style and fear of flourine that I end up
           | recognizing.
        
         | mech422 wrote:
         | I love that column :-) 'foof' is more then a cpu bug :-P
        
       | _Microft wrote:
       | I knew that cyclobutane existed (a ring of four carbon atoms with
       | attached hydrogen atoms which is 'weird' in the sense that the
       | angles between the bonds are not what would be expected for a
       | carbon atom with four bonds [0]) but learned about the existence
       | of ladderanes today. Their structure looks just soo unusual.
       | 
       | https://en.wikipedia.org/wiki/Ladderane
       | 
       | Speaking of unusual structures, here is something like a 2D
       | version of a ladderane:
       | 
       | https://en.wikipedia.org/wiki/Fenestrane
       | 
       | [0] https://en.wikipedia.org/wiki/Orbital_hybridisation#sp3
        
         | divbzero wrote:
         | I glanced at the structures first before reading the text and
         | assumed they were oddballs synthesized in the lab. It's
         | incredible that these are all natural products. Leptocillin
         | also looks astonishingly weird.
        
         | jihadjihad wrote:
         | It's interesting that one group of compounds is named using the
         | Latin, in this case for "window" (fenestrane), but "ladderane"
         | makes use of an ordinary English word (by way of Old English
         | and Germanic).
         | 
         | I guess I would have expected a Latin-derived name like
         | "escalane" instead.
        
           | _Microft wrote:
           | Follow the first link/s in these articles and somewhere you
           | will find ,,jawsamycin". A part of this molecule looks a lot
           | like a row of teeth...
        
             | Someone wrote:
             | _Shark_ teeth (https://mobile.twitter.com/germhuntermd/stat
             | us/1285971314134...)
        
         | kccqzy wrote:
         | And the last example from the article, a tetrasubstituted
         | cyclobutane, probably tells you that the functional groups
         | connected to the cyclobutane could alleviate some of the ring
         | strain in plain cyclobutane.
         | 
         | Similarly, cyclopropane also has incredible ring strain and
         | likely won't be found in nature, but plenty of derivatives can.
        
       | echelon wrote:
       | I'm ever conflicted with the opposing forces of climate change
       | and meeting the energy needs of our growing and innovative
       | civilization.
       | 
       | Evolution has produced a bountiful assortment of living,
       | breathing solutions that fit into every nook and cranny of our
       | biological state space. Millions of years of adaptation have
       | produced sometimes incredibly niche systems that beautifully
       | capture all of the energy available to them. The biochemical
       | pathways nature discovers are fascinating and complex and of an
       | altogether different nature than what our human innovation
       | capital can find or produce.
       | 
       | So it's incredibly depressing that we're losing all of this
       | amazing biodiversity. A moss or fungus might have more
       | information in its genes - biochemical pathways, metabolic flux,
       | finely tuned balance, encodings of adaptations beyond our
       | understanding, etc. etc. - than the sum total of all human
       | thought thus far. And that's not even considering the non-
       | molecular, ecosystem and even biogeochemical impact these losses
       | can have.
       | 
       | But if we stop building and consuming and making, the plates come
       | crashing down. Our sun burns out. The universe will never know of
       | us.
       | 
       | It's all so complicated. I'm glad we can appreciate these little
       | wonders, though.
       | 
       | Thank you for posting this article. Chemistry is beautiful.
        
         | Maursault wrote:
         | > Chemistry is beautiful.
         | 
         | It is, but as a species, we have been astoundingly
         | irresponsible with it and continue to be, for profit.
        
         | EdwardDiego wrote:
         | > The universe will never know of us.
         | 
         | If there is anything out there with the capacity to "know",
         | perhaps one day they'll find our ruins and compose some art
         | along the lines of Shelley's poem Ozymandias. As I've been
         | enjoyed the sci-fi of Adrian Tchaikovsky of late[0], I hope
         | that it's sentient octupuses who can express the tragedy and
         | mystery of our downfall in a dance of colour and movement.
         | 
         | [0]: https://lareviewofbooks.org/article/we-are-going-on-an-
         | adven...
        
       | rossdavidh wrote:
       | "Pipline" -> "Pipeline"
        
         | rossdavidh wrote:
         | An odd thing to downvote...
        
         | _Microft wrote:
         | Thanks, fixed!
        
       | zamalek wrote:
       | "Extractions and Ire" on YouTube has been having a go at
       | synthesizing a cubane, while the creator does "meme" a lot, it is
       | good chemistry. And a really weird molecule.
        
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       (page generated 2022-03-23 23:00 UTC)