[HN Gopher] 'Fingerprint' ML Technique Identifies Different Bact...
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       'Fingerprint' ML Technique Identifies Different Bacteria in Seconds
        
       Author : NotAWorkNick
       Score  : 25 points
       Date   : 2022-03-06 12:52 UTC (10 hours ago)
        
 (HTM) web link (news.kaist.ac.kr)
 (TXT) w3m dump (news.kaist.ac.kr)
        
       | throwthere wrote:
       | I guess the clinical relevance depends on how well you can tailor
       | treatment based on it. AFAIK if docs don't know a) the specific
       | bug and [1] b) its antibiotic resistance and c) the patient is
       | seriously or potentially going to be seriously ill they start out
       | with broad spectrum anyway.[2]
       | 
       | Since the fingerprint technique doesn't tell you antibiotic
       | resistance the real benefit is probably identifying rare bugs
       | early and to some degree avoiding broad-spectrum stuff and
       | slowing down the sort of antibiotic resistance bacteria develop
       | over a population over time.
       | 
       | [1] Docs can genrally guess the type of bug, or at least the
       | class of bug, and even "narrow-spectrum" antibiotics can cover
       | multiple classes
       | 
       | [2] For less serious infections docs go by likelihood tables and
       | population features (ie-- UTIs are generally killed by X in this
       | region of the world/country). If that treatment fails, they try
       | another one.
        
         | chewbacha wrote:
         | I'm even less impressed because it looks like for their tests
         | they used a rod and a cocci which are pretty different
         | morphologically. If it could differentiate between group a and
         | b strep or staph id be very impressed.
         | 
         | But also; many times it's not just the antibiotic resistance
         | but virulence that's mediated by a plasmid and there are any
         | visual distinctions. The effect would be biochemical in nature
         | so a visual analysis would provide limited benefit.
        
       | [deleted]
        
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       (page generated 2022-03-06 23:01 UTC)