[HN Gopher] Regulation of neurotransmitters by gut microbiota, e...
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       Regulation of neurotransmitters by gut microbiota, effects on
       cognition (2021)
        
       Author : _Microft
       Score  : 84 points
       Date   : 2022-02-06 19:07 UTC (3 hours ago)
        
 (HTM) web link (www.ncbi.nlm.nih.gov)
 (TXT) w3m dump (www.ncbi.nlm.nih.gov)
        
       | hoppyhoppy2 wrote:
       | see also https://news.ycombinator.com/item?id=30235378 on a
       | similar topic
        
       | sydthrowaway wrote:
       | I'd like to know the effect of Lion's Mane!
        
         | 34679 wrote:
         | Paul Stamets on the benefits of Lion's Mane:
         | 
         | https://www.youtube.com/watch?v=wmB6_boALVs
        
         | Loeffelmann wrote:
         | Lions mane always sounds like pseudoscience to me.
        
           | sydthrowaway wrote:
           | Scientifically proven to have NGF!
        
       | readthenotes1 wrote:
       | TL;DR: That voice in your head saying gimme sugar? It's coming
       | from your gut. Now for some ice cream.
        
       | lioeters wrote:
       | Not sure it's relevant but.. The last couple of months I've been
       | eating kilos of grapefruits - I like it peeled, parted, and
       | frozen. I feel that it's improving my bodily health, inside
       | (digestive system) and out (skin), and also my mind somehow. I'm
       | learning several new languages (programming and human) in
       | parallel, and it seems like my thoughts have become more clear
       | and precise, as well as nimble. What I'm realizing is that my
       | whole life I've been lacking fruits, just because I never liked
       | eating them - but I found that I love frozen grapefruits, it's
       | delicious. Weird.
        
         | dralley wrote:
         | Fresh grapefruit is fantastic, the problem is that the s** that
         | they sell in the grocery stores is not fresh. It's picked far
         | too early and then artificially ripened in transit.
         | 
         | Never tried frozen though.
        
           | tayo42 wrote:
           | I never really liked a lot of fruits except some berries
           | until I had them local and in season while traveling. It's
           | like different food. Idk why that crap even gets sold
           | sometimes.
        
         | ghotli wrote:
         | https://www.atlasobscura.com/articles/grapefruit-history-and...
         | 
         | The bland URL doesn't do that article justice, this is a great
         | read.
        
         | jayd16 wrote:
         | Glad you found a missing link on your diet. Be aware that
         | grapefruit can interact with some medications. Just make sure
         | to check if you're eating that much.
        
         | bin_bash wrote:
         | do you find them sour? Perhaps frozen it would be less so but I
         | can't eat grapefruit without making some crazy faces. And I
         | generally like sour flavors.
        
         | jeremygaither wrote:
         | For many people taking a range of medications, especially
         | mental-related medications, eating grapefruit can cause a large
         | range of negative side effects. Several medications will become
         | inert in the presence of citric acid and vitamin C. Oranges, if
         | eaten at the appropriate times during their medication regimen
         | (usually an hour after or before medication), is usually safe.
         | Fiber is also important, but it can also absorb medications and
         | render them inert if taken at the wrong times. Fiber is usually
         | safe two hours before or after medication, which can be
         | difficult to orchestrate, depending on medication regimens.
        
           | hirvi74 wrote:
           | This is the first I have ever read about fiber causing issues
           | with medications.
           | 
           | What effects does fiber have on certain medications and why?
           | Does it slow the absorption rate due to the medication being
           | dispersed in the fiber?
        
           | bawolff wrote:
           | Wouldn't that be the Furanocoumarin not the vitamin c?
        
           | _Microft wrote:
           | This topic has its own Wikipedia entry:
           | 
           | https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_intera.
           | ..
        
         | colordrops wrote:
         | Have you tried the giant pomelos? Good pomelos are very easy to
         | peel and the skin comes right off the pink flesh, and have
         | perfectly tart and sweet flavor. Much better than ordinary
         | grapefruit. I ate these daily when I lived in Asia.
        
       | BirAdam wrote:
       | This has always fascinated me. This is also not at all unique to
       | humans.
       | 
       | I have a cavy (Guinea pig, she had a cage mate but the cage mate
       | passed) and she had a bladder stone. It was really big. After she
       | passed it with some assistance from the vet, she got a really bad
       | infection. Apparently, the stone cut her up on the way out. She
       | had to go on antibiotics for quite a while and the medicine
       | killed off her gut flora. This made a mess, made her really
       | uncomfortable, and it smelled. So, I needed to figure stuff out.
       | There were three steps really. First, she needed medical food to
       | make sure she was getting everything she needed. Second, she had
       | to take some benebac, and third as cavies are coprophagic, I got
       | some poop from a healthy pig and mixed it in to some of her food.
       | She recovered and seems to be happier and more calm than ever.
       | 
       | Gut bacteria is apparently super important in every mammal. No
       | idea about birds, reptiles, or arthropods or fish.
        
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       (page generated 2022-02-06 23:02 UTC)