[HN Gopher] It Will Make Scientific Sense to Offer Booster After...
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       It Will Make Scientific Sense to Offer Booster After Three Months
        
       Author : Geeflow
       Score  : 17 points
       Date   : 2021-12-10 15:15 UTC (7 hours ago)
        
 (HTM) web link (www.spiegel.de)
 (TXT) w3m dump (www.spiegel.de)
        
       | dahfizz wrote:
       | From 100% effective, to there's still a chance you get Covid and
       | die, to maybe 6 months of protection, now down to needing a
       | booster every three months. Disappointing.
       | 
       | The pfizer vaccine trials ended over a year ago[1]. Why are we
       | only finding out about the reduced protection now? If the vaccine
       | only works for three months, we should have known about that 10
       | months ago.
       | 
       | [1] https://www.pfizer.com/news/press-release/press-release-
       | deta...
        
         | TechBro8615 wrote:
         | Is this really the first time you're hearing this news? It's
         | been clear and supported by data for months.
        
       | mark_l_watson wrote:
       | This is in agreement with what my personal doctor told me: the
       | vaccines work great for two months, lots of protection. He said,
       | depending on individual circumstances, protection decreases
       | rapidly after that. His concern is people thinking that they can
       | stop being careful after getting a vaccination. I just finished a
       | company offsite and they tested everyone every morning and sent
       | out test kits to protest for a few days before the offsite
       | meeting. I liked that degree of carefulness.
        
         | dkdk8283 wrote:
         | That sounds horrific, I would much rather opt out of that event
         | instead of going through that.
         | 
         | I refuse to live in fear.
        
           | jsnell wrote:
           | I assume you also don't wear a seatbelt?
        
             | xboxnolifes wrote:
             | Please spell out the parallels. I am lost.
        
       | joemazerino wrote:
       | Man who works for company which profits from boosters says we all
       | need boosters.
        
         | JanSt wrote:
         | Read the article. This claim is adressed. It's scientific
         | consensus.
        
           | mjfl wrote:
           | the science says that one vaccination is still sufficient to
           | prevent severe disease, and that it is uncertain that
           | additional boosters will reduce transmission on a country
           | wide basis- things will still spread among the unvaccinated,
           | booster hold outs, and those whos antibody titers have gone
           | down after 3 months. It is absolutely not scientific
           | consensus, then, that universal boosters are necessary or
           | would be sufficient to end the pandemic.
           | 
           | I absolutely would not recommend getting a vaccine booster
           | shot every 3 months. Your plasma cells are not meant to
           | proliferate to that extent.
        
             | 1123581321 wrote:
             | Yes, and in addition to that, the regimen of shots and
             | boosters becomes too much for unvaccinated to contemplate.
             | They are more being asked to enter into a new lifestyle,
             | now, contrasted with the request a year ago to take one
             | simple protective action.
             | 
             | In the US, I would like to see the recommendation change to
             | a single Pfizer shot with second shot and booster language
             | changed to that of optimization, rather than necessity. The
             | single shot, even after several months, is still very
             | effective against severe cases. I believe the vaccination
             | rate would increase and that pressing to get our 1+ shot
             | rate above 90% could be a genuine bipartisan rally.
        
           | akomtu wrote:
           | It's not a consensus when anyone who objects is fired from
           | academia.
        
           | deadmutex wrote:
           | Ironically, this post is next to:
           | https://news.ycombinator.com/item?id=29493241.
        
           | disambiguation wrote:
           | Yup, case closed.
           | 
           | And on a completely unrelated note:
           | 
           | https://www.npr.org/sections/thetwo-
           | way/2016/09/13/493739074...
        
             | V__ wrote:
             | This is such a dumb whataboutism point. Either discredit
             | the data or the argument.
        
               | disambiguation wrote:
               | No this isn't whataboutism.
               | 
               | My point is simply that "scientific consensus" has lost
               | some of its brand value.
               | 
               | Further, I'm not an "expert" so even if I did challenge
               | the data or argument, I would be dismissed for being
               | unqualified.
        
               | ziddoap wrote:
               | > "Here is the scientific consensus."
               | 
               | >> "What about sugar."
               | 
               | Is the definition of whataboutism.
               | 
               | > _Further, I 'm not an "expert" so even if I did
               | challenge the data or argument, I would be dismissed for
               | being unqualified._
               | 
               | Not always true. You just need to provide data (or
               | identify an error in their data/methodology/etc.) that is
               | convincing enough to overcome the difference in weight
               | afforded to an expert opinion and non-expert opinion.
               | 
               | Extraordinary claims require extraordinary evidence. This
               | is not to say that you are wrong, you very well could be
               | correct, but the onus is on you to prove why your non-
               | expert opinion should be weighted higher than hundreds of
               | experts from various countries.
        
               | lolsal wrote:
               | I don't think the parent is saying "what about sugar?", I
               | think the parent is saying "why should we buy that this
               | is consensus when consensus can be bought and paid for,
               | as evidenced by this story about sugar and scientific
               | consensus?"
        
               | ziddoap wrote:
               | In other words, "what about the the time when consensus
               | was bought?".
               | 
               | And my reply would be: if you have evidence that the
               | current consensus has been purchased, I am all ears.
        
               | kcplate wrote:
               | And my reply would be that evidence is not always
               | immediately apparent, but that doesn't mean evidence
               | doesn't exist.
               | 
               | The commenter's point was that due to other scandal,
               | "scientific consensus" doesn't hold the same weight it
               | once might have held. Especially when powerful industries
               | and Lot's O'Money are involved. Not just sugar, but
               | energy, tobacco, and yes...even other pharmaceuticals.
               | TBH there seems to be a pretty direct correlation between
               | any industry that tends to be regularly described as "Big
               | [name of industry]" and these sort of scientific oopsies
               | that turn up a decade or so later.
               | 
               | I'm fully vaccinated and boosted, but I am not going to
               | be at all surprised if 10 years from now there is an
               | "oops" with this too.
        
               | disambiguation wrote:
               | It's always amazing to find people that are strongly
               | "programmed" with discussion patterns. If "what about"
               | then "dismiss claims". Nuance and critical thinking take
               | a back seat.
               | 
               | This isn't whataboutism.
               | 
               | Whataboutism is reacting to "black lives matter" with
               | "all lives matter".
               | 
               | It's a defensive argument to protect against your
               | opponent shifting the goal posts.
               | 
               | However, it doesn't apply when your subject is a function
               | of its context. In other words, whataboutism doesn't work
               | when 2 subjects depend on each other, as they do here.
               | This isn't "what about sugar", this is "how do we know
               | there's no conflict of interest".
               | 
               | The onus is not on me to prove anything about the
               | booster, it's on them to prove that they're worth
               | listening to.
               | 
               | If you want evidence, then you probably didn't read my
               | link because the evidence for sugar didn't emerge for
               | years after the fact. Dealing only in absolutes is
               | absurd.
               | 
               | Life is like poker, by the time you have all the
               | information it's already too late.
        
       | tamaharbor wrote:
       | Do you think natural immunity has any impact? If it turns out
       | that Omicron has mostly mild symptoms, why can't we infect the
       | young and physically strong and forget about endless vaccines and
       | boosters.
        
       | LatteLazy wrote:
       | How much of the problem (contagion, hospital busyness) is lack of
       | booster and how much is people who haven't had any doses?
        
       | ipspam wrote:
       | Wow! I miss a free and fair press that asks relevant questions.
       | 
       | This exchange would NEVER happen in North America:
       | 
       | DER SPIEGEL: Is it also possible that the next variant will
       | already be here before you even start production?
       | 
       | Sahin: I've been thinking hard over the past few days about why
       | we're actually seeing a variant like Omicron right now, what
       | caused it. In doing so, I remembered being concerned about one
       | thing earlier this year: In people with suppressed immune
       | systems, the virus might get too much time to accumulate
       | mutations and evolve. It appears to me that this is exactly what
       | happened with Omicron: The virus has been able to undergo a
       | prolonged evolution in a small group of people.
       | 
       | DER SPIEGEL: Was that an unfortunate coincidence, or are such
       | strongly mutated variants a constant threat?
       | 
       | Sahin: It certainly could happen more often. Basically, it's like
       | this: Once Omicron spreads, the virus variant that comes after it
       | will have to come up with something new to make the leap into the
       | next generation. We would then be constantly facing a new
       | pathogen.
        
         | findalex wrote:
         | > It certainly could happen more often.... We would then be
         | constantly facing a new pathogen.
         | 
         | If? Isn't this how contagious respiratory diseases always work?
        
         | cblconfederate wrote:
         | Can't we extrapolate the rate of new strains from the existing
         | cold coronaviruses which circulated widely?
        
       | xchaotic wrote:
       | No matter what the science about the microbiology of this, the
       | social science says that people will not comply with this.
       | There's also the logistics of it. There must be a better way.
        
       | diggernet wrote:
       | Recently here on HN, user 'native_samples' said, "anything based
       | on their mRNA tech became toxic after multiple doses. That's why
       | they refocused on vaccines".[1]
       | 
       | Now we are talking about more and more frequent vaccine booster
       | doses. Shouldn't that be a concern?
       | 
       | [1] https://news.ycombinator.com/item?id=29306624
        
       | rurban wrote:
       | Looking at the curves it only makes sense for Pfizer/Biontec.
       | 
       | Moderna holds 6 months on a 80% level. But the Moderna risk is a
       | bit higher for younger, so the 3 months boosters are for the
       | younger ones.
       | 
       | But this is all outdated with Omicron. They need adapted boosters
       | first. Or wait for the real risk analysis. As it looks like
       | COVID-19 goes the way of all such waves. The best surviving
       | mutations get weaker and more infectious, until they end at the
       | common cold. Omicron is extremely weak so far. Let's hope it
       | stays that way
        
       | akomtu wrote:
       | Pfizer must be in a tough position now: it has to demonstrate
       | consistent YoY growth and the only way to do that is endless
       | booster mandates.
        
         | titusjohnson wrote:
         | They don't have to demonstrate YoY growth. They would like to
         | but they certainly don't _have_ to. This is especially true for
         | profits derived from acts of god.
        
       | cblconfederate wrote:
       | Why not offer alternatives? Like working from home, limited
       | crowding, wearing FFP2 masks etc. I hate jabs they make me dizzy
        
         | DiabloD3 wrote:
         | Anyone on HN understands these magic words: defense in depth.
        
           | lolsal wrote:
           | It's fine to lock down and dictate what a server can do. It's
           | not fine to do that to free people in perpetuity.
           | 
           | Constant boosters, lockdowns, etc are burning lots of good
           | will offered by people who originally opted to compromise
           | personal liberty for the greater public good. It's getting
           | old and the ROI of the compromise is getting smaller every
           | day.
        
       | shimonabi wrote:
       | I got vaccinated the first day I could and got the 3rd dose last
       | week.
       | 
       | My mother got the 3rd dose a few weeks before me and on the 3rd
       | day one of her lower-legs went numb. She had some therapy in the
       | hospital and is OK now, but I'm afraid how she could react to a
       | possible future vaccination. I'm not even sure the vaccination
       | was the cause.
       | 
       | I have many antivaxx coworkers and I would never mention
       | something like that in front of them. Just today the most
       | fanatical of them called in sick with "the flu". He doesn't even
       | want to get tested for Covid.
        
         | dkdk8283 wrote:
         | My friends wife lost an eye due to complications from a
         | booster.
         | 
         | The vaccine has real side effects, the faster we can have a
         | civic conversation about it the better off we all are.
         | 
         | I have severe cardiovascular problems and cannot get the
         | vaccine. I'm judged and called an antivaxxer all the time. It's
         | not us vs them, we're all in it together.
         | 
         | Being open and honest is always the best path. Especially when
         | you disagree.
        
           | BlackjackCF wrote:
           | Your friend's wife and you are absolutely not antivaxxers.
           | You're the folks that we're trying to protect with herd
           | immunity via vaccination, because you cannot get a vaccine.
           | 
           | I'm sorry you're being judged, that's awful.
        
           | TheNewsIsHere wrote:
           | I agree that everyone is a bit quick to judge, and I'm sorry
           | you're more vulnerable because of a preexisting condition.
           | And I'm sorry to hear of that kind of complication from any
           | medication. I hope she was able to make a claim and get
           | compensation through the adverse effects program (assuming
           | you're in the US).
           | 
           | My dad gets the flu shot each year. He's not an anti-vaxxer.
           | The COVID shot seems different though.
           | 
           | My dad still refuses to get a vaccine because all he hears is
           | mis- and disinformation. He's recently changed to "leaning
           | toward getting the shot," which is great, but he wants to
           | drive another family member around this weekend who is
           | currently suffering from COVID-19.
           | 
           | Being open and honest with him, I told him the most likely
           | outcome for him, and even held back on how grim his
           | particular prognosis would likely be given his risk factors.
           | But people don't want to hear the reality.
           | 
           | That reality is that these vaccines are, statistically, safe
           | and effective for the vast majority of the population. (I
           | know that you weren't asserting otherwise, and that you
           | aren't in that majority.) There comes a point when refusal to
           | engage with that reality in typical circumstances becomes a
           | dividing line. It might be fear driven for those who don't
           | have a contraindicated condition, but it's hard not think of
           | refusal by people in medically typical circumstances, at this
           | point, to be precious and selfish.
        
             | hbrav wrote:
             | I find your story very interesting, because it's a pattern
             | I've heard several times before: someone who does not want
             | to get vaccinated because of the risk of side effects, but
             | is willing to expose themselves, to a greater degree than
             | is necessary, to the risk of covid.
             | 
             | It seems that for some people there's an intrinsically
             | greater distrust of vaccines (a synthetic thing) than
             | disease (a natural thing).
        
           | peakaboo wrote:
           | Hacker news routinely removes comments about the vaccine
           | dangers and calling it flame bait, and itches to ban me or
           | anyone else who talks about those things.
           | 
           | It's a long time since we were in this together. It's against
           | the people who don't vaccinate now.
        
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       (page generated 2021-12-10 23:02 UTC)