[HN Gopher] How will the covid pills change the pandemic?
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       How will the covid pills change the pandemic?
        
       Author : amichail
       Score  : 3 points
       Date   : 2021-11-21 21:52 UTC (1 hours ago)
        
 (HTM) web link (www.newyorker.com)
 (TXT) w3m dump (www.newyorker.com)
        
       | coolso wrote:
       | I think the worst affected by these pills will be the ones who
       | enjoy shaming others for not getting the vaccine. For many, that
       | has been the central point of their identities now since around
       | January or so, and it will probably be a difficult transition
       | period for them moving forward.
        
       | holonomically wrote:
       | > A full course, which needs to start within five days of the
       | appearance of symptoms, consists of forty pills--four capsules
       | taken twice a day, for five days.
       | 
       | I don't understand the logic involved here. Why would anyone be
       | willing to take 40 pills for 5 days straight but unwilling to get
       | a vaccine shot?
        
         | coolso wrote:
         | Two huge reasons: one, ingesting a potentially harmful
         | substance has almost always been considered far less dangerous
         | than getting it injected into you. Hence aversion to needles,
         | blood, etc. Ever seen COPS? Even the most experienced police
         | officer will "freak" at the sight or suspicion of a needle and
         | everything changes.
         | 
         | Secondly, and this one applied to me: given how new the vaccine
         | is, and the slight chance of heart inflammation and blood
         | clotting among other things, many people would rather passively
         | get COVID through no fault of their own, and very likely
         | recover from it easily like most, rather than purposefully get
         | a shot which means they're directly playing a role in, in their
         | mind, potentially bringing harm to themselves.
         | 
         | I waited 8 months of general availability of the vax, and then
         | I was comfortable enough with the (lack of) side effects to
         | overcome fear #2.
        
           | holonomically wrote:
           | I guess that makes sense but the side-effects seem overblown
           | in my opinion. Even with being susceptible to the side-
           | effects it is very unlikely that catching the virus
           | unwittingly is going to be better. I haven't found any
           | studies on comparative outcomes with respect to the virus vs
           | the vaccine when it comes to side-effects but whatever I
           | could find so far indicates that for those that are
           | susceptible to the side-effects of the vaccine the virus is
           | much worse because it attacks all tissues indiscriminately.
        
         | pwg wrote:
         | Possibly the difference between "I (metaphorical "I") don't
         | think I will encounter it." vs. "Oh ...., I have contracted a
         | case of it from somewhere."?
         | 
         | Many often change their attitude when things go from "an
         | unknown risk of possible future encounter" to "certain to have
         | contracted".
        
           | holonomically wrote:
           | The virus is endemic so we're already in the certain
           | scenario. That's why I don't understand the logic of people
           | that refuse vaccination. You can either take 40 pills for 5
           | days or you can get vaccinated and avoid the hassle entirely.
           | Deferring the decision just guarantees you will take the 40
           | pills, there is no way to avoid contracting the virus
           | anymore.
        
             | throwawaylinux wrote:
             | Or you can do neither and if you are otherwise healthy it
             | isn't much to worry about.
             | 
             | Conversely, people with other health problems or who are
             | terrified of covid might get both.
        
               | holonomically wrote:
               | Being otherwise healthy is no guarantee that you are not
               | genetically susceptible to cytokine storm reaction to the
               | virus. The vaccine preps the immune system to avoid over-
               | reacting, whether you are otherwise healthy or not does
               | not really make a difference because no one can control
               | their genetics and how it will interact with novel
               | viruses. [1]
               | 
               | 1: https://www.nejm.org/doi/full/10.1056/NEJMra2026131
        
               | throwawaylinux wrote:
               | Being otherwise healthy is a massive factor in outcome
               | though, and reduces the risk an order of magnitude or so,
               | to levels many people don't care about very much.
        
               | holonomically wrote:
               | The point is that even for healthy individuals the odds
               | are stacked against them if they catch the actual virus
               | instead of getting the vaccine and prepping their immune
               | system ahead of time. [1]
               | 
               | 1: https://www.theguardian.com/world/2021/aug/04/fit-and-
               | health...
        
         | smt88 wrote:
         | It is a lot easier to get someone to take drugs when they're
         | feeling sick than when they're feeling healthy.
        
           | holonomically wrote:
           | Seems very irrational but I agree it explains the logic of
           | the people who are hopeful they are somehow immune to getting
           | sick from an endemic virus.
        
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