[HN Gopher] Suicides among Swedish men decreased after Viagra be...
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Suicides among Swedish men decreased after Viagra became more
affordable
Author : hheikinh
Score : 119 points
Date : 2021-10-10 18:58 UTC (4 hours ago)
(HTM) web link (sapienjournal.org)
(TXT) w3m dump (sapienjournal.org)
| canjobear wrote:
| Time series correlations like this have next to no evidentiary
| value.
| [deleted]
| mertd wrote:
| Read the paper maybe? There is a clear regime shift in the
| suicide data. Maybe there is some other trigger. But the
| argument of the paper is not without merit.
|
| [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159839/
| spindle wrote:
| I don't agree with this paper's statistical analysis, and I
| think there's probably a different trigger for the change
| _BUT_ I came here to say that I strongly agree with you that
| the paper has to be taken on its specific merits. It 's
| perfectly possible to have good epidemiology based on time
| series data.
|
| (I feel like I should cite something. It's been a long time
| since I was a professional epidemiologist and I'm way too
| lazy to look up anything recent, but Oli Miettinen's book
| "Theoretical Epidemiology" is an example of how some
| epidemiologists are very clever and very careful.)
| erosenbe0 wrote:
| Right. I use the example that the number of circulating guns in
| the USA always increases.
|
| So you pick a ten year period where per-capita homicide rate
| went up or down to 'prove' whatever correlation you want about
| guns and homicide.
| delaaxe wrote:
| Just reading the title reminded me of
| https://i.redd.it/4h8emlr5z3c41.jpg
| mhh__ wrote:
| Well, internet use -> computer use -> better economics +
| indoors more often.
|
| Contrived but not ridiculous
| mam3 wrote:
| How long before we see the "suicide dropped when lsd, magic
| mushrooms and MDMA are legalised"
| rc2634 wrote:
| After we see "mental illness increased when lsd, magic
| mushrooms and MDMA are legalized"
|
| These drugs have huge potential to mess up a person's brain if
| not taken with caution and under direct supervision of experts.
| mam3 wrote:
| You really need to abuse for a super long time some lsd to be
| messed up. I know a wide bunch of people in the party scene
| who absolutely abuse MDMA but they dont have more mental
| illness than the avetage smoker
| aaaaaaaaaaab wrote:
| Well, the hangover after rolling can be pretty scary for
| someone who's already prone to depression.
| mam3 wrote:
| Well you need to educate people for sure..
| uoaei wrote:
| Pre-load 5-HTP for a week
| adflux wrote:
| I once accidentally took about 500mg (tested). Felt depressed
| for weeks. Everything felt wrong on my skin. It gave me an
| understanding of what it means to be depressed. Few weeks
| later I was fine again. But definitely a scary experience. I
| began to hallucinate parts of conversations. Then the muscles
| (?) In my ear started to feel really painful. Then I realised
| I had actually taken too much
| mam3 wrote:
| 500 is way too much (even if you are from the UK lol).
|
| Its 5 times the fun dose. Try doing that with some other
| drugs and it can be life threatening..
| tayo42 wrote:
| hallucinating on mdma is wild, no one seems to mention it
| really
| ArtB wrote:
| Yes! I wish this was known. Mine lasted a couple of days.
| Thought I'd never feel joy again.
| beebeepka wrote:
| It's a well known problem. Finishing the night with any
| kind of actual sex (not masturbation) greatly mitigates the
| depression stage.
| zie wrote:
| Yet more proof men are obsessed with their genitals.
| agumonkey wrote:
| Does viagra affect the brain too or is it (as I assumed) mostly a
| mechanical booster (more blood to your genitals) ?
| Traubenfuchs wrote:
| PDE5 inhibitors improve dementia, so they definitely do
| something good to the brain. Truly wonderdrugs.
|
| https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705107/
| agumonkey wrote:
| from a quick glance it seems PDE5 are mostly part of the
| cardiovascular system metabolism, I was more wondering about
| direct neurological effects.
| aaaaaaaaaaab wrote:
| It can make your vision blue: https://gizmodo.com/why-viagra-
| tints-your-vision-blue-168517...
| klyrs wrote:
| I've heard that it can give horrendous headaches, bad enough to
| put a fellow off the mood.
| praptak wrote:
| I guess it's the increased blood flow to the head. Same
| reason the porn industry aren't huge fans of Viagra - it
| tends to make the face red.
| aaaaaaaaaaab wrote:
| For most porn stars Viagra et al is useless, because you
| still need to be "in the mood" for it to work. Most male
| talent are so desensitized to sex, that they must resort to
| other substances that they inject directly into the penis,
| like Papaverine [0]. Of course that comes with its own set
| of challenges, like the risk of prolonged erections, called
| priapism [1], which sometimes can only be stopped by
| surgically draining the stale blood from the penis.
|
| [0] https://en.wikipedia.org/wiki/Papaverine
|
| [1] https://en.wikipedia.org/wiki/Priapism
| agumonkey wrote:
| I'm looking for research into the neurological basis of
| arousal (not necessarily erection, which is only a small
| part of it). If anybody knows, spam me.
| faeyanpiraat wrote:
| I might have something related which might interest you,
| also looking for info on your topic. How can I get in
| contact?
| agumonkey wrote:
| check my profile, it should list my mail
|
| thanks already
| eurasiantiger wrote:
| Bullshit.
| ianhawes wrote:
| What a terrible day to be literate.
| Flow wrote:
| It affects blood flow by relaxing muscles that constricts blood
| vessels. It was originally intended as a blood pressure
| medication.
| Traubenfuchs wrote:
| Sildenafil (Viagra) is old and busted. Tadalafil (Cyalis) has a
| longer duration of action and less side effects (17 vs 4 hours
| half life) due to a lesser reduction of PDEs besides the targeted
| PDE5.
|
| Additionally, studies show that daily tadalafil is much better in
| managing or even "curing" ED.
|
| Want a little extra boost? Consume 6g of L-Citrullin a day. One
| of the few proven, freely and cheaply available substances that
| improve erections. L-Citrulline gets converted to L-Arginin and
| is better that L-Arginin supplementation.
|
| If you want to increase the half life, consume pomegranate juice.
|
| Warning, L-Citrullin and PDE5 inhibitors potentiate each other.
|
| Need even more arguments? Daily PDE5 inhibitors are
| cardioprotective and cardioregenerative.
|
| Studies used 5mg Tadalafil daily, I am on 20 -why not?
|
| https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261690/
| tzs wrote:
| Careful with pomegranate juice if you take any prescription
| medications. It doesn't get along with several, including some
| popular blood pressure medicines.
| PrincessJess wrote:
| Maybe just stop jerking off so much, dude. Jesus.
| [deleted]
| adflux wrote:
| 6mg? I think you mean 6g.
| Traubenfuchs wrote:
| correct
| koboll wrote:
| Yeah I'm not really sure why anyone uses Viagra when Cialis
| exists.
|
| As long as you don't have heart or blood pressure problems,
| it's perfectly fine for healthy people to take, and even if you
| don't have ED it elevates you to a sex god. Truly amazing
| stuff.
| kabes wrote:
| I tried both and get headaches from both. So I'd prefer a 4h
| headache vs a 24 hour headache
| vagrantJin wrote:
| Im not entirely at that point in my life yet but here here -
| I'm going to be buy 10 litres of Pom juice and recording the
| data. Hopefully recording useful data.
| Traubenfuchs wrote:
| There is only weak evidence it increases sildenafil half life
| -I shouldn't have mentioned it.
| dillondoyle wrote:
| Does anyone have experience supplementing L-Citrulline for
| sports performance?
|
| I tried beta-alinine and I couldn't do it; made me have this
| horrible uncomfortable pin pricking/itchy reaction for over an
| hour each dose.
| AdrianB1 wrote:
| Are you asking about amateur or profesional sports? I
| competed in amateur mountain bike races for a number of
| years, but I never took any medication to improve performance
| and I see no point in doing that. As an amateur, going to
| competitions every couple of weeks and getting in the top
| quarter was the purpose, not winning it; it was a strong
| enough motivator to do sport - the atmosphere, the tracks and
| the views in the forests were a great reward.
|
| For profesional level, medics can tell what is allowed and
| what is not. I am not a doctor, but most performance-
| improving drugs are forbidden.
| nradov wrote:
| Citrulline isn't on the WADA prohibited substances list.
| redis_mlc wrote:
| > I never took any medication to improve performance and I
| see no point in doing that.
|
| FYI: for a small percentage of participants, the only
| reason to compete is to win.
|
| Most of the stars you've heard of (Tiger Woods and Michael
| Jordan come to mind) simply wouldn't play if they couldn't
| win. Tiger actually said that in an interview, and
| Michael's coach said the need to win was the secret to his
| success.
|
| So the reasons behind PEDs are:
|
| 1) to maintain competitiveness with people on them
|
| 2) to ensure wins if that's the reason you're there.
| Traubenfuchs wrote:
| What kind of performance?
|
| We always got our all star creatine.
|
| I didn't notice any changes in workout performance from
| tadalafil or l-citrulline and I consumed insane amounts of
| them.
| dillondoyle wrote:
| I would assume protein synthesis from what I've read?
|
| The research on creatine does seem like it's not total BS
| in some specific cases. For instance I'm pescatarian and it
| seems like that I might get an actual benefit with lower
| non-meat creatinine. At first I definitely felt what was
| probably psychosomatic but I can't tell if it's helping
| still.
| Scarbutt wrote:
| Doesn't tadalafil affect your sleep? Also, it doesn't feel
| nice if you take it and seat in front of the computer for
| four hours doing focus stuff.
| fierro wrote:
| I use it for bodybuilding. Helps with the pump. It's in a lot
| of pre-workouts.
| dillondoyle wrote:
| 'the pump' would be valuable to me if that means reducing
| lactic acid or enabling you to push further (I'm a
| climber)!
| faeyanpiraat wrote:
| Do you happen to know any drug or supplement which helps
| Preventing an erection?
|
| (Serious question)
| Redoubts wrote:
| HRT
| the_lonely_road wrote:
| Not exactly what you are looking for but maybe it will help
| you anyway, assuming you are trying to prevent erections
| literally and not sexual desire. Grip your thigh muscles
| together as tight as you can, like you are trying to squeeze
| an imaginary grape centered at the middle of each thigh and
| hold the grip for a minute. Wording it a different way make
| sure you are flexing the thigh muscles as hard as you can.
|
| For some reason I have no explanation for , this does wonders
| to almost immediately eliminate unwanted erections. I'm an
| old man with chronic prostatitis and tons of urine related
| issues including frequent unwanted erections with no
| connection to arousal and have never had the gumption to talk
| about this with anyone else im real life so it may not work
| for everyone. Good luck to you either way.
| Traubenfuchs wrote:
| So many come to mind, I could write a whole article about it.
|
| None of them have an acceptable side effect profile, many of
| them can potentially cause persistent inability to have sex
| to the point where not even megadoses of pde5 inhibitors
| help.
|
| I strongly advise against ever taking SSRI or 5ari for this
| purpose. They are now known to cause persistent ED in
| susceptible individuals.
| throwaway902109 wrote:
| If your issue is Sleep Related Painful Erections (SRPE), then
| Baclofen works well.
| adventured wrote:
| Drugs that lower testosterone will typically accomplish that
| outcome. Men that go through prostate cancer treatment for
| example will often have erectile dysfunction (due to hormone
| therapy targeting testosterone - androgen deprivation
| therapy).
| Traubenfuchs wrote:
| Pretty much every drug that lowers your T or DHT to the
| point where you can't get an erection anymore can
| permanently ruin your (sex) life.
| jnwatson wrote:
| SSRIs tend to reduce libido. That's not exactly the same
| thing, but they are connected.
| AdrianB1 wrote:
| There is a widely circulated rumor that in the Romanian army
| they used to put a small quantity of bromide (sodium or
| potassium? don't know) in the evening tea; it is not supposed
| to prevent an erection, but total lack of sexual desire. This
| was 30-40 years ago, I was not able to find any official
| documents related to that, but any men over 50 years old is
| telling that story.
| orbital-decay wrote:
| This legend circulated across the entire Eastern Bloc in
| general, and possibly beyond it. It's not based on
| anything.
| Trias11 wrote:
| Great way to get PM's from girls :)
| boopmaster wrote:
| I took wellbutrin for depression once, and I tolerated that for
| less than two weeks. Can confirm: no release valve = even worse
| depression.
| zdragnar wrote:
| Most antidepressants really do take several weeks (4-6) to
| "work". I use quotes there because we don't really understand
| how or why they work, and there is more to alleviating
| depression than taking a pill. Cognitive behavioral therapy,
| developing a healthy routine, and alleviating environmental
| stressors are also important.
|
| That said, I do so much better with all of that plus lexapro
| that I dont know if I'll ever stop taking it.
| manux wrote:
| A more nuanced take on this:
| https://www.youtube.com/watch?v=21NxJS_zYDY
| DantesKite wrote:
| The CIA used it to bribe tribal leaders in Afghanistan too.
| abdel_nasser wrote:
| and divorce rates skyrocketed right before a swedish divorce
| reform of some kind went through which made it less financially
| beneficial for women to initiate the divorce. and this surge of
| divorces was, as always, almost all women initiating.
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