[HN Gopher] The challenge of finding new tools to fight prostate...
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       The challenge of finding new tools to fight prostate cancer
        
       Author : Tomte
       Score  : 43 points
       Date   : 2021-09-11 19:04 UTC (2 days ago)
        
 (HTM) web link (arstechnica.com)
 (TXT) w3m dump (arstechnica.com)
        
       | motte wrote:
       | There are a lot of overgeneralized statements here and facts that
       | border on misleading. Metastatic prostate cancer is relatively
       | rare and most patients with prostate cancer generally pass from
       | other diseases long before pc progression
        
         | Johnny555 wrote:
         | Isn't that what they said?
         | 
         |  _The 10-year life expectancy for localized prostate cancer is
         | around 98 percent. It's remarkably curable. Many prostate
         | tumors are so slow-growing and nonthreatening, they're not even
         | treated--they're simply monitored to make sure they stay
         | nonthreatening. "You're more likely to die with prostate cancer
         | than of prostate cancer," says Dr. Isla Garraway, director of
         | research in the Department of Urology at the University of
         | California, Los Angeles (UCLA)._
        
         | 123409871234 wrote:
         | It's not particularly rare. Even if prostate cancer will only
         | kill a small percentage of men that have it, it's such a common
         | cancer that it still ends up killing around 34,130 men a year
         | in the US making it the second leading cause of cancer death in
         | men in the US. Figures are similar for other countries.
         | 
         | source: https://www.cancer.net/cancer-types/prostate-
         | cancer/statisti...
        
       | [deleted]
        
       | zwieback wrote:
       | Super interesting read. I had prostate cancer 15 years ago at age
       | 40 and had my prostate surgically removed, fully recovered now
       | but it was stressful. It's great to see so much progress in the
       | diagnostic field since the decision to have surgery is not an
       | easy one. It's almost like there are two versions: the one you
       | can live with for a long long time and the kind that kills you
       | quick. Since the PSA test is so sensitive but not terribly
       | specific a lot of men have to make a call based on pretty low-
       | quality information, better diagnostics will go a long way toward
       | helping in that area.
       | 
       | Paradoxically, for me the PSA test now is a great tool. Since
       | it's very sensitive anything other than zero is a sign something
       | is going on, if you still have your prostate PSA bounces around
       | quite a bit even if you don't have cancer so it's a terrible
       | first diagnostic.
        
       | trashface wrote:
       | Tip for men with PC: if you just get surgery and your PSA is high
       | after that surgery, don't put off followup treatment (radiation
       | usually). My brother did that and its now metastatic in his
       | bones. 5 year survival rate for that in US is 30%.
        
       | Johnny555 wrote:
       | As someone with low-grade prostate cancer, the thing I'm most
       | hoping for (for now) is better imaging or other monitoring tools
       | since I'm looking at getting a biopsy every other year or so. The
       | biopsy itself isn't too bad as far as medical procedures, but
       | each one has a risk of infection so I wish there were a less
       | invasive way. I'll get MRI's too, but they don't work as well at
       | detecting small cancerous areas, my MRI missed the cancer that a
       | subsequent biopsy found.
       | 
       | Though I also wouldn't mind targeted immunotherapy that could
       | target the cancer without any invasive procedures, chemicals or
       | radiation.
        
         | [deleted]
        
       | WarOnPrivacy wrote:
       | _It has one of the highest early-stage survival rates of any
       | cancer,_
       | 
       | I guess it does if one has usable health insurance. The scores of
       | millions of Americans who don't - I guess they make up a lot of
       | that death rate.
        
         | Johnny555 wrote:
         | I'm not sure that's true - for many (most?) people with low-
         | grade prostate cancer, it's not going to end up being what they
         | die of and can just be ignored. There's debate about whether or
         | not PSA screening is leading to too much unnecessary cancer
         | treatment.
         | 
         | So it's possible that doing nothing at all is as good as more
         | screening and early treatment.
        
         | conductr wrote:
         | I wish I was joking, but those folks often don't make it into
         | the "early-stage" cohort because they don't get the simple
         | routine healthcare that would allow for early
         | detection/diagnosis
        
       | barrenko wrote:
       | I've been having mild to discomforting prostate issues for the
       | last 5 years, if anyone has advice, I'm listening.
       | 
       | Doctor still won't prerscribe medication since I'm young, only
       | taking natural supplements, which do work when I'm not stressed.
        
         | AuryGlenz wrote:
         | You might want to figure out why they won't give them to you
         | (because you're young seems odd to me), but you can buy all
         | sorts of medications direct from India.
        
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