[HN Gopher] Caffeine and theanine exert opposite effects on atte...
       ___________________________________________________________________
        
       Caffeine and theanine exert opposite effects on attention (2017)
        
       Author : chalst
       Score  : 225 points
       Date   : 2021-07-21 13:00 UTC (10 hours ago)
        
 (HTM) web link (pubmed.ncbi.nlm.nih.gov)
 (TXT) w3m dump (pubmed.ncbi.nlm.nih.gov)
        
       | jonnycomputer wrote:
       | >Caffeine reduced flanker conflict difference scores on the
       | Attention Network Test (p < 0.05), theanine increased difference
       | scores (p < 0.05), and the combination did not differ from
       | placebo. Thus, under emotional arousal, caffeine and theanine
       | exert opposite effects on certain attentional processes, but when
       | consumed together, they counteract the effects of each other.
       | 
       | Haven't seen the actual paper yet, but generally reduced
       | difference scores is taken as "better" performance on a cognitive
       | control tasks. Which would mean, caffeine better than theanine,
       | and better than caffeine plus theanine. Don't really know that
       | however, because you lose information when you take a difference
       | score. For example, caffeinated individuals may suddenly find
       | non-emotional stimuli just as distracting as emotional stimuli,
       | and so difference between conditions disappears. That's why its
       | important to note the change in all conditions (emotional vs non-
       | emotional flankers) in all experimental groups.
        
         | pvarangot wrote:
         | They used "highly arousing negative film clips and pictures" to
         | stimulate, so since it's negative clips under that kind of
         | stimuli coffee would be worse.
        
       | MaryBoyagi19 wrote:
       | They are both good in the right proportions, harmony matters
        
       | w4llstr33t wrote:
       | Anecdotally I've found that taking some l-theanine with coffee
       | helps takes some of the edge off of the caffeine.
        
       | peteretep wrote:
       | My (previously medicated) anxiety disorder has disappeared since
       | I stopped drinking more than one coffee a day and started
       | supplementing with l-theanine.
        
         | CountDrewku wrote:
         | If you get anxiety from bodily sensations then caffeine is no
         | bueno. It pretty much gives you the initial sensations of a
         | panic attack then sets you off from there.
        
         | deagle50 wrote:
         | Which brand?
        
           | peteretep wrote:
           | With the caveat that I am sure it doesn't matter, Puritan's
           | Pride 200mg
        
       | klhutchins wrote:
       | Anecdotally, Caffeine+L-Theanine makes my anxiety worse and my
       | ability to focus severely decreased, basically the opposite
       | effects of what people seem to achieve with this combo.
        
         | paraph1n wrote:
         | As compared to caffeine alone? Or as compared to nothing?
        
       | jvanderbot wrote:
       | Theanine has been shown to have a noticeable relaxation without
       | sedative effect, and a minor decrease in anxiety, within minutes
       | of ingestion.
       | 
       | Yes, there are problems with all studies, and it sure is fun to
       | pile on, but a cursory search of examine.com confirms my own
       | experience and that of amateur noot-ers: Theanine takes the edge
       | off caffeine and helps focus. Caffeine+Theanine is the third
       | highest recommended home treatment for focus (behind exercise and
       | sleep) on r/nootropics for whatever that's worth.
       | 
       | You can find other studies here:
       | https://examine.com/supplements/theanine/
       | 
       | I take it semi-regularly during times I'm over-consuming
       | caffeine, but find that I come to resent its absence when I stop
       | taking it.
        
         | blacksmith_tb wrote:
         | I always take theanine with my caffeine (that is, I drink tea).
        
           | markus_zhang wrote:
           | Interesting. As a Chinese I used to drink tea but years ago I
           | switched to coffee for better flavour. Maybe I should try
           | milk tea instead.
        
             | cyberpunk wrote:
             | Don't give up on the flavour, there is a massive range of
             | Chinese tea that's indescribably amazing. I mean, duckshit
             | oolong, da Hong pao, puerh...
        
               | wil421 wrote:
               | I worked at an American Chinese restaurant that had
               | fantastic oolong tea. Whenever I bought it from Asian
               | supermarkets it was literally the worst quality tea I've
               | ever tasted, below the Lipton tea that's for making sweet
               | tea.
        
               | Vrondi wrote:
               | Look for "Tie Guan Yin" (Iron Goddess of Mercy) Oolong.
               | It's a lovely starting point. Usually good across most
               | brands. Medium-light and naturally floral/fruity quality
               | to it. The amount you use and the temp and time for
               | brewing are also different for Oolong compared to black
               | teas.
        
               | cercatrova wrote:
               | Buy online, check out the /r/tea wiki [0] and
               | specifically the user vendor list [1]
               | 
               | [0] https://old.reddit.com/r/tea/wiki/faq
               | 
               | [1] https://old.reddit.com/r/tea/wiki/vendors/page_01
        
               | blacksmith_tb wrote:
               | Part of the problem there is that the domestic market
               | consumes most of the best grades of all types of teas.
               | But it's possible to get really amazing Chinese and
               | Taiwanese teas from tea importers in the US[1] and EU.
               | Some of them are pricey, but not all (and tea is
               | generally not too expensive per cup, compared with lots
               | of other beverages).
               | 
               | 1: https://www.uptontea.com/teas/c/oolong-
               | tea/pgsize/12/filter/...
        
               | minsc__and__boo wrote:
               | I've found Pu Erh tea is a great transition as a coffee
               | drinker. It has that strong earthy/malty flavor, even if
               | it doesn't have the caffeine.
               | 
               | Just make sure you buy it from a brick instead of the
               | loose leaf (which tends to be lower quality imo).
        
               | pvarangot wrote:
               | Pu Erh is great but you have to be careful with it if you
               | have low blood pressure. I learn't the hard way after I
               | once brewed some after having a beer and straight down
               | passed out in the kitchen, like fell to the floor passed
               | out. I do have low blood pressure and usually took Pu Erh
               | while sitting down but after that I just stopped taking
               | it allover.
        
               | skindoe wrote:
               | Lonjing
        
           | jvanderbot wrote:
           | I've recently switched over to green tea and really wish I
           | had earlier.
        
             | actually_a_dog wrote:
             | What did you switch from? Coffee? Coffee has some decent
             | health benefits as well, but probably isn't so great for
             | your anxiety levels. :-)
        
               | jvanderbot wrote:
               | Yes from coffee. I was almost at a pot/day and it was not
               | helping.
        
               | wil421 wrote:
               | I switch to espresso a couple years ago and never looked
               | back. A double shot latte in the AM is enough to keep me
               | going and I don't need a full pot. If I'm especially
               | tired I'll do a straight espresso shot in the afternoon.
        
         | asadkn wrote:
         | I have personally observed something similar with black tea but
         | I am not sure if's just the theanine + EGCGs or something else.
         | 
         | A while back, I noticed that 'chai' helps me focus and relax
         | (improved mood, less anxiety, etc.) at the same time. It's made
         | of milk, black tea, cardamom, cinnamon, and negligible/no sugar
         | (personal preference).
         | 
         | I prefer coffee in terms of taste, but of all the things I have
         | tried, this has been the best for me. Black tea alone doesn't
         | have the same effect on me, nor does green tea, or coffee with
         | or without milk/cream/sugar.
         | 
         | So I wonder if it's the combination that matter and not
         | theanine alone.
        
           | ValentineC wrote:
           | > _A while back, I noticed that 'chai' helps me focus and
           | relax (improved mood, less anxiety, etc.) at the same time.
           | It's made of milk, black tea, cardamom, cinnamon, and
           | negligible/no sugar (personal preference)._
           | 
           | I know Starbucks et al market the above as 'chai', but I
           | think 'masala' (as in 'masala chai' [1]) should be the
           | keyword.
           | 
           | [1] https://en.wikipedia.org/wiki/Masala_chai
        
           | ac29 wrote:
           | > It's made of milk, black tea, cardamom, cinnamon, and
           | negligible/no sugar
           | 
           | Maybe you mean no added sugar? Milk has 1.5g of sugar / oz
           | (about half that of orange juice, as a comparison).
        
         | sizzle wrote:
         | I use l theanine everyday to avoid heart palpitations with
         | coffee. Is there any long term damage I'm doing from this daily
         | combo??
        
         | reader_mode wrote:
         | >Caffeine+Theanine is the third highest recommended home
         | treatment for focus (behind exercise and sleep) on r/nootropics
         | for whatever that's worth.
         | 
         | I'm surprised modafinil isn't no. 1
         | 
         | I don't use it regularly to avoid developing a tolerance, but
         | that thing has a profound impact on the ability to focus and
         | power through, nothing else I've tried comes even close. I
         | guess speed/amphetamine but that gets me euphoric and I notice
         | elevated heart rate, I don't feel any different on modafinil
         | other than focused and tiredness being blocked.
        
           | likeabbas wrote:
           | Interesting. My anecdotal experience with modafinil is that I
           | get extreme anxiety and elevated heart rate without any
           | additional focus benefits. In fact, it detriments my ability
           | to focus.
           | 
           | Adderall on the other hand, while stimulating and euphoric,
           | gets the job done. But it works so well that I have trouble
           | focusing without it now. I've tried tapering off multiple
           | times but always go back to it when my work quality suffers
           | and I'm not contributing to tasks that my team needs done.
        
             | jvanderbot wrote:
             | Paranoid suspicion was my #1 effect. No thanks.
        
               | hda111 wrote:
               | Modafinil or Methylphenidate? Modafinil never made me
               | paranoid but I know at least one person with psychosis
               | caused by Methylphenidate.
               | 
               | I avoid both nowadays because work isn't worth risking
               | health.
        
               | likeabbas wrote:
               | What are the health risks with either?
        
               | likeabbas wrote:
               | For Modafanil or Adderall?
        
             | reader_mode wrote:
             | I got that the second time I used modafinil and went with
             | whole pill (did half the first time). Later on I did whole
             | pills every time and had no sideffects (a couple of times I
             | would get noticeably elevated HR, but I was awake 12+h at
             | that point and need moda to get through the night)
        
               | likeabbas wrote:
               | What dosage? I've tried 25mg, 50mg, 100mg and 200mg doses
               | for Modafanil at different stages for a month. I was
               | really trying to get off of Adderall at the time, but
               | nothing really worked for me.
        
               | reader_mode wrote:
               | 200mg worked for me, started with 100mg to see if I would
               | get sideffects, but I never used it over 2-3 days in a
               | week.
        
               | likeabbas wrote:
               | Different strokes for different blokes, I guess.
        
           | meepmorp wrote:
           | -afanils don't work for everyone. Modafinil makes me both
           | jittery and tired, and I can't focus for more than a minute;
           | kind of like I'm badly jet lagged and just need to pass out.
        
           | unwaryquerier wrote:
           | Do you have a site you use to purchase your modafinil? And
           | how did you decide dosage?
           | 
           | EDIT... and it looks like this is a controlled substance. I
           | didnt know
        
             | reader_mode wrote:
             | Gf had a huge stash she ordered from India years back. I
             | almost ran through them over the years so will need to
             | restock but it doesn't seem as big of a deal as getting rec
             | drugs, more like ordering steroids
        
             | JohnBooty wrote:
             | I'm not sure about HN policy here regarding linking to such
             | things. For a couple of years I ordered from Afinil
             | Express, who have semirecently changed their name to Shark
             | Mood. You can guess/Google the URL. For security you'll
             | definitely want to use cryptocurrency and not a credit
             | card; apparently the issue is shady overseas card
             | processors and not the merchant(s) themselves FWIW.
             | 
             | As far as dosage, it's really trial and error I suppose.
             | Generally each pill is meant as a single dose AFAIK. You
             | can always dip your toes in the water by starting off with
             | 1/4 or 1/2 a pill.
             | 
             | I generally do 1/2 a pill before breakfast and 1/2 a pill
             | before lunch (on work days) and roughly half that amount on
             | off days.
        
             | astrange wrote:
             | It's only schedule IV. The other stimulants are schedule II
             | because they can be abused.
        
           | 01100011 wrote:
           | My problem with Moda/Armoda is that I feel like a tweaker
           | when I'm on it, and I only take enough to get an effect. I
           | get sweaty, physically stressed, and just generally feel like
           | I'm taking something that is not in my body's best interests.
           | I have to drink liters of water to avoid a headache. I also
           | have noticed some of the dopamine effects(increased risk
           | taking and addictive behaviors). I'm slightly bipolar
           | though(type II, pretty mild) so maybe it's just not for
           | people like me.
           | 
           | It does work pretty well for focus though, and is really nice
           | for my middle-aged brain which often is tired throughout the
           | day.
        
           | espresso_enigma wrote:
           | re. Modafinil, I heard it mentioned by a reputable programmer
           | on twitter and decided to try it. I used it regularly for
           | several years, and it was extremely useful in helping with
           | focus and staying on task. I feel like it helped me in a
           | breakthrough phase of my career. The problem I found was that
           | I could only tolerate it 2-3 times per week over the long
           | term. Any more than that, and the edgy/anxious/irritable side
           | effects would build up to intolerable levels. Not to mention
           | I was buying from questionable sources online, figuring it
           | would be too difficult to talk a doctor into prescribing me
           | some.
           | 
           | Eventually though I worried about the quality of the batched
           | I was getting online and stopped taking it altogether. But I
           | still really struggled with focus on a daily basis and
           | started to wonder if what I was really doing was self
           | medicating for undiagnosed ADHD. Thinking back on my life it
           | did sort of fit. Though I am a "successful" developer and I'm
           | doing fairly well at life, it has always felt like I had to
           | struggle and fight a lot more than the average person just go
           | get through the day and stay on task. So I talked to a
           | doctor, tried ritalin and adderall and have settled on a low
           | dose adderall routine that really works for me. It helps
           | tremendously with focus and motivation, and if I am diligent
           | about maintaining a good diet/exercise/sleep schedule, the
           | side effects are very manageable with daily use. I still
           | think about the modafinil days, because those were good
           | times, and it was fun to have that all day I'm on fire
           | feeling. Adderall is nice, but I can tell that if I upped my
           | dose to get into the realm of intense focus that Modafinil
           | used to give me, I would also be getting pretty "high" and
           | the comedown side effects would probably be more unpleasant.
        
             | cauliflower2718 wrote:
             | Have you been at a low dose for a long time? Is there
             | something you do to reduce tolerance?
        
             | MivLives wrote:
             | I daily take modafinil, actually prescribed to me. I have
             | bad problems when I take either ritalin or adderall. Not
             | being able to sleep for over 24 hours, and panic attacks
             | being some of the more annoying ones. Modafinil on the
             | other hand the difference is more subtle, where if I try I
             | can focus but I'm not trying to focus on something.
             | 
             | Highly recommend anyone considering it talking it over with
             | their doctor first. The dose they sell via grey market can
             | be rather high especially if you haven't had it before.
        
               | JohnBooty wrote:
               | Highly recommend anyone considering it talking
               | it over with their doctor first.
               | 
               | Do folks generally have luck getting it prescribed for
               | ADHD and its ilk these days?
               | 
               | The doctors I've mentioned it to were not receptive to
               | prescribing it off-label for attention disorders.
               | 
               | They didn't really seem to think it was an awful idea per
               | se but really couldn't endorse it, and naturally they
               | were worried about the risks of ordering it from
               | possibly-unreliable overseas pharmacies.
        
               | cauliflower2718 wrote:
               | I haven't been able to get modafinil for ADHD (n=1). I
               | have heard of people getting prescriptions for modafinil
               | because of their work schedules (e.g. being tied to the
               | hours of a stock exchange in a different time zone).
        
           | sizzle wrote:
           | Have you tried Dexedrine? It's the right handed enantiomer of
           | adderall which has less pronounced effects on heart rate,
           | etc.
        
           | pvarangot wrote:
           | The nootropics community is usually more about substances
           | with reliable effects across the whole spectrum of neural
           | fauna. Modafinil has side effects that are really bad for
           | productivity in a substantial percent of the population, like
           | it doesn't work or it's really bad for some people with GAD
           | or OCD and people prone to addiction or with ASD.
           | 
           | I'm not a proponent of having drugs be "prescription only",
           | people should be allowed to eat what they want if they don't
           | harm anyone else... but I personally put Modafinil under my
           | list of stuff that you probably may need some help with if
           | you want to try it.
        
             | netizen-936824 wrote:
             | Could you please expand on what you mean by "neural fauna"?
             | I'm not sure I understand what you're referring to.
        
               | pvarangot wrote:
               | Everyone's brain is different and substances may don't
               | affect everyone in the same way. Like how some people get
               | addicted to coffee or cigarettes and some don't, some
               | people get the benefits of Modafinil without the side
               | effects and some don't. Cognitive disorders are one way
               | to categorize this but it can be more complex than that.
               | People with OCD or GAD are an extreme example, there's a
               | lot of different personality types and brain structures
               | out there, that's the "neural fauna" I'm talking about.
        
           | LeifCarrotson wrote:
           | I'm sure it's primarily because caffeine and theanine are
           | culturally accepted and available cheaply over-the-counter.
           | Modafinil is prescription-only (at least in the US), and
           | speed/amphetamines are likewise illegal.
           | 
           | Instead of asking your doctor for psychoactive drugs or
           | delving through the dark corners of the internet or dark
           | corners of downtown alleys, you can get caffeine at Walgreens
           | or Starbucks.
        
             | reader_mode wrote:
             | But the two aren't even comparable in terms of effect IMO.
             | I already have caffeine tolerance so at this point I'm
             | drinking coffee out of habit and not to go through
             | withdrawal, but even when I reset my tolerance a few times
             | getting back into it does almost nothing compared to
             | modafinil (aside from getting jitters when I overdo it)
        
               | ceedan wrote:
               | I just skimmed r/nootropics and it seems like the side
               | effects and prescription requirement of modafinil
               | disqualify it as a home recommendation.
               | 
               | If the recommendations were purely about effectiveness
               | all recommendations would likely be prescriptions...
        
           | odiroot wrote:
           | > I'm surprised modafinil isn't no. 1
           | 
           | Someone shared modafinil with me once. The effect is crazy.
           | 
           | As you say, it lets you focus on single task for quite a long
           | time, without feeling tired. And I'm saying it as a person
           | who can be easily distracted.
           | 
           | I never tried it again, not to mess with my brain.
        
             | JohnBooty wrote:
             | It has that effect for me... but unfortunately I don't
             | always get to choose the task. Sometimes I'll get really
             | interested in the wrong thing, as opposed to work.
             | 
             | But overall I do find it beneficial and preferable to
             | Adderall.
        
             | reader_mode wrote:
             | Yes, same thing, I get distracted easily, but modafinil is
             | like a cheat code to getting stuff done.
        
         | Florin_Andrei wrote:
         | Simple protocol: one coffee cup in the morning to wake up.
         | Green or black tea through the day as needed.
        
         | tayo42 wrote:
         | Within minutes? Are you snorting it? can anything get through
         | you that quickly orally? Sounds like placebo
        
           | netizen-936824 wrote:
           | If consumed dissolved in a liquid on an empty stomach, it can
           | be absorbed rather quickly.
        
       | taeric wrote:
       | Neat that the point is that they offset each other. Not just that
       | they have opposite effects used individually, but when combined
       | they are no different from a placebo.
       | 
       | I'll have to dive more on what the local processing means.
        
       | SavageBeast wrote:
       | Commencing self experiment in 3,2,1...
       | 
       | Combining with this other little jewel found on HN earlier this
       | afternoon:
       | 
       | https://sudo.fm/?ambience=1,50|2,50
        
       | rupertdev wrote:
       | I've taken L-Theanine in the morning with coffee, but I found
       | that it seems to limit the effects of my stimulant medication for
       | ADHD, which I suppose makes sense. I will likely try taking it in
       | the afternoon if I drink another cup of coffee.
        
         | raducu wrote:
         | I vaguely remember theanine helped me sleep.
         | 
         | I've had bad sleep forever, but since I've started concerta, my
         | sleep is worse than ever.
         | 
         | Guess I should give theanine another shot.
        
         | ck425 wrote:
         | Interesting. In what way? I just started a generic version of
         | concerta and so far haven't found L-Theanine to have any
         | negative effect, though I mostly get it from green tea and only
         | take it in supplement form.
        
       | dukeofdoom wrote:
       | I noticed when I switched from cream to oat milk, the coffee hits
       | a little differently. It feels stronger. I'm not sure if its some
       | interaction with milk. But paper should consider what is consumed
       | with the coffee too. Some people will add sugar, and some even
       | add butter.
        
         | PascLeRasc wrote:
         | Have you tried drinking it black as well? I wonder if it's
         | added sugar that a lot of oat milks have or something drowsy-
         | inducing in milk.
        
           | minsc__and__boo wrote:
           | Oat milk has more carbs than the rest of the alt (?) milks,
           | and sometimes more than cow. Def could be the reason for
           | feeling better.
        
           | dukeofdoom wrote:
           | I haven't really. I switched to Oatmilk, because I was
           | getting stomach cramps about once a month. Still haven't
           | figured out if the milk was causing it, because it happened
           | again after the switch. Maybe its something in the coffee,
           | maybe the pesticides they use or maybe I don't clean the
           | coffee machine frequently enough. I drink as many as 5 cups
           | in day. So I'm might have a bit of a problem.
        
         | bserge wrote:
         | I'm... using caffeine powder sublingually... Fast acting, no
         | stomach problems.
         | 
         | Different brands have noticeably different strength, though,
         | gotta be careful. The less bitter the powder, the better imo.
        
           | holdenlucas wrote:
           | In your experience, what is the brand with the least bitter
           | powder?
        
             | bserge wrote:
             | Having tried half a dozen brands, I prefer Scitec Nutrition
             | 100mg caffeine capsules.
             | 
             | Pretty much the least bitter powder I tried, and the
             | effects come on slow and steady.
             | 
             | I'm really curious what they do differently when extracting
             | caffeine.
             | 
             | Most other brands have a comparably more dry powder that
             | hits like a truck for me even at (supposedly) the same
             | dosage.
        
         | swader999 wrote:
         | Coffee might bind to the cream more and then absorb slower. I
         | notice with a teaspoon of butter I get a much less jittery
         | experience. (The bullet coffee thing).
        
         | pixelbreaker wrote:
         | possibly the lipids in cow's milk slow the ingestion of
         | caffeine. depends on the oat milk you drink and how much fat it
         | has in its ingredients.
        
           | scns wrote:
           | Oat milk has added vegetable oils like sunflower, which have
           | higher amounts of unsaturated fats i think. Someone mentioned
           | coconut oil, which is high in satarated fat, could make a
           | difference.
        
         | CountDrewku wrote:
         | Probably something to do with the fat. There's something called
         | bulletproof coffee or butter coffee where they add
         | butter/coconut oil/mct oil and I think it's supposed to satiate
         | you more as well as keep you from getting all jittery.
        
       | GNOMES wrote:
       | Copious amounts of coffee + ltheanine was very popular on my
       | college campus around midterms/finals.
        
         | LeifCarrotson wrote:
         | I used them heavily in college, then less in my early
         | professional life, then more heavily when I had very young
         | kids, now back to what feels like a reasonable 100mg caffeine +
         | 200mg L-theanine a day.
         | 
         | My life improved significantly when I realized that I was
         | drinking soda, energy drinks, or coffee for the caffeine, not
         | the taste or "nutrition": they're all extremely acidic, and
         | some are extremely sugary.
         | 
         | Instead of drinking my drugs, I drink from a water bottle and
         | take a slow-release pill each morning with my multivitamin.
        
           | sunshineforever wrote:
           | That's such a great idea... I've done this with cigarettes
           | and I've had similar thoughts about how I no longer enjoy
           | coffee either.
        
       | thomasfl wrote:
       | I simply can't understand why it is still uncommon to sleep at
       | the office, while they give this psychoactive drug called
       | caffeine for free.
       | 
       | According to wikipedia, caffeine is the world's most widely
       | consumed psychoactive drug.
        
         | mbil wrote:
         | Since working from home due to the pandemic I've been able to
         | wean myself completely off caffeine. To not get tired in the
         | afternoons, I take a 15-20 minute nap each day after lunch. I
         | think this has been good for me, and I'm worried that when I
         | have to go back to the office I'll be dependent on coffee
         | again.
        
           | stronglikedan wrote:
           | I wish I could nap. For me, a nap turns one normal day into
           | two short days - a bright productive one and a dark groggy
           | one. I've even tried the coffee-then-20-minute-nap method to
           | no avail.
        
             | gknoy wrote:
             | My wife and I are the same way -- we never seem to feel
             | refreshed from midday naps. Is there something we're doing
             | wrong? :)
        
             | dalmo3 wrote:
             | > For me, a nap turns one normal day into two short days -
             | a bright productive one and a dark groggy one.
             | 
             | Same here, but the productive one is _after_ the nap!
        
         | unmole wrote:
         | It's fairly common in China. Sure you have to 996 but that
         | includes an hour for napping post lunch.
        
           | ehnto wrote:
           | First time hearing of 996, for anyone else curious that's a
           | 9am-9pm 6 days a week work schedule.
        
             | ValentineC wrote:
             | Do also check out https://996.icu/#/en_US :)
        
             | rpmisms wrote:
             | That's disgusting.
        
         | swader999 wrote:
         | You need to master the art of sleeping in your office chair
         | with your back to the door. Keep an interesting piece of paper
         | handy to be reading when someone comes in instead of staring at
         | a blank screen.
        
         | newsbinator wrote:
         | If you sleep at the office you're wasting time and slacking.
         | 
         | If you can keep your eyes open while staring at an open email
         | you're being productive.
        
           | jack_riminton wrote:
           | This guy corporates
        
             | toxik wrote:
             | Please don't turn this place into reddit.
        
               | jack_riminton wrote:
               | This guy hacks
        
           | CountDrewku wrote:
           | Sadly this is the truth. It's all about perceived work and
           | not actual work.
        
       | bitshiftfaced wrote:
       | I have a theory that the jittery/anxious feeling people say they
       | get from caffeine is mainly due to the size of the dose and
       | "quickness" of it. If you find that theanine fixes it, then
       | great. But I'd also suggest trying 100 mg time-release caffeine
       | and see how it goes. You might be surprised. This also has the
       | benefit of needing less total caffeine while lasting you longer
       | through the day. (Just a heads up: many brands only say they're
       | time-release but don't seem to actually have the
       | coating/capsule/matrix that you'd expect from an actual time-
       | release pill.)
        
         | toxik wrote:
         | Agreed, if I drink a lot of strong coffee fast, I'm basically
         | shaking for the next hour or so.
         | 
         | My solution is dilution. I put about four cups worth of coffee
         | into the filter, and then 1.3 L water in the tank. The result
         | is very weak coffee that you can drink throughout the day,
         | keeping you mildly caffeinated and hydrated simultaneously.
         | 
         | If you're making coffee for people who can't accept watery
         | coffee, just brew normally and add water afterwards. The
         | Italians in the office will curse your name, but that's just a
         | sign you're doing it right.
        
           | eloff wrote:
           | I don't like watery coffee, so I mix mine 2/3 decaf. I have
           | 4-5 cups throughout the morning. It keeps it a nice, even
           | caffeine hit.
        
           | ehnto wrote:
           | The Italians in your office would have wanted espresso!
           | 
           | That's actually an interesting point, we're generally talking
           | about coffee as if it's all the same, but I see people here
           | talking about instant grounds, drip coffee and then there is
           | espresso, I'm sure they all work out quite different. If
           | you're used to grinding your own beans you'll know different
           | beans have different caffeine amounts, and different
           | extraction methods all have different yields.
           | 
           | Where I am it's all espresso, thanks to Italian immigrants
           | bringing over stovetop espresso kettles in the 40s and
           | jumpstarting our now incumbent coffee culture. I've never
           | even seen a drip coffee machine, it's espresso machines in
           | petrol stations, offices, cafes, restaurants, people's homes.
           | 
           | If I pull an espresso shot for too long it's going to have
           | more caffeine in it than had it pulled really quickly, even
           | though it's the same amount of coffee/water solution in the
           | cup. So one person's four cups a day is rarely going to match
           | another persons four cups a day. I'm sure it's the same for
           | instant coffee brands or grinds too, when you take it all
           | into consideration it's going to be hard to know what
           | caffeine intake anyone has.
        
             | toxik wrote:
             | Right but there are standard serving sizes so "four cups
             | worth" is a well-defined amount, subject to cultural
             | variations I'm sure.
             | 
             | What you call stovetop espresso we call mocha, which is
             | decidedly not espresso in my book. I also find the amount
             | of caffeine in espresso laughable, but I'm also
             | Scandinavian and we drink some pretty dark coffee
             | apparently.
        
               | ehnto wrote:
               | At least where I am, mocha is coffee + chocolate + milk,
               | which is strange, because another common name of the
               | stovetop espresso machine is a "Moka Pot", named after
               | the Yemeni city of Mocha. A confusing fun fact for the
               | day.
               | 
               | My main point was that there isn't a well defined amount
               | of caffeine in any measure of 'four cups'. If you have
               | four cups of Moka Pot coffee and I have four cups of your
               | dark coffee, I'm going to be buzzing while you'll you be
               | cursing the Alfonso Bialetti for daring to invent the
               | device. Even if you consider 'shots' of coffee to be a
               | measure, each bean/blend/grind will deliver different
               | mounts of coffee. I think it's just worth noting if we're
               | trying to discuss the effects of caffeine, as people tend
               | to speak in cups per day. It sounds like you would be
               | very disappointed with four cups of my coffee!
        
               | ValentineC wrote:
               | Adding to the confusion: there's also the Mocha varietal
               | for Arabica coffee beans. :)
               | https://en.wikipedia.org/wiki/Mocha_coffee_bean
               | 
               | This looks like an excellent writeup for anyone
               | interested: https://dailycoffeenews.com/2019/02/07/the-
               | coffee-roasters-c...
        
         | ehnto wrote:
         | I drink my coffee over the course of a few hours, if I have to
         | slam it down, say I suddenly need to leave the office, it makes
         | me feel incredibly anxious and shaken. Taken slowly it has no
         | noticeable effect except to my ability to get tired a tonight,
         | I drink it entirely for the taste so that's actually a bummer.
         | I've considered switching to decaf.
        
       | zachruss92 wrote:
       | This isn't super surprising based on my personal experience. I
       | take theanine in the morning to help clear my mind before working
       | and also before bed to stop my mind from racing.
       | 
       | I have found that taking caffeine and other prescription
       | stimulants(Adderall)have a negative effect in some ways
       | increasing my anxiety or otherwise hindering my ability of
       | outside-the-box thinking. Subsequently I have stopped taking
       | Adderall completely for about a month now and I feel a ton
       | better.
        
         | mombul wrote:
         | I see a lot of people say "I take theanine" but what do you
         | mean exactly? You just drink tea or does it come in other
         | forms?
        
           | singhrac wrote:
           | L-theanine is readily available in supplement form in the US
           | (e.g. $6 for a bottle of 100 pills). I don't take it
           | regularly but that's mostly because I haven't examined the
           | evidence carefully.
        
           | lm28469 wrote:
           | Probably supplements. Be careful about what you buy though,
           | internet is full of random "made in china" supplements
           | containing god knows what
        
           | meowkit wrote:
           | It comes in natural things like mushrooms / green tea, but
           | its also synthesized in capsules / powder / products like
           | neurogum.
        
       | hfjtntnfjfk wrote:
       | This is the kind of paper that yesterday article about how we
       | should assume all medical research is fraudulent warned about.
        
         | v77 wrote:
         | Yeah, holy crap, if your alarm bells aren't ringing from the
         | moment you start reading a paper like this by now I don't know
         | what to tell you.
        
           | bodhi_mind wrote:
           | Alarm bells? I'm not sure I follow. What's "this" kind of
           | paper? Their methods seem rational. Many references on
           | previous research are mentioned. Do you think we're being
           | gaslighted or something?
           | 
           | I wouldn't use this paper to make life decisions on my mental
           | health or assume theanine will give me super powers, but
           | that's with all research. Nothing exists in a vacuum and
           | shouldn't be interpreted that way. Overall, I'd say this is
           | potentially interesting for someone researching these
           | chemicals.
        
           | mumblemumble wrote:
           | Has anyone actually read the paper? I hit a paywall.
           | 
           | And the abstract doesn't even give enough information to
           | describe what they actually found. It gives p-values, but not
           | effect sizes.
        
             | actually_a_dog wrote:
             | Googling the title didn't find me any full-text PDFs, but
             | sci-hub should have it.
        
             | hfjtntnfjfk wrote:
             | N=36 and testing protocol of 4 servings over a short period
             | of time is all you need to know.
             | 
             | Even if you assume all they find is true, the effect could
             | disappear or change into something else one month after
             | initiation (dose accommodation, etc...)
        
               | maininformer wrote:
               | "As you know from teaching introductory statistics, 30 is
               | infinity." -Gelman
        
               | soperj wrote:
               | Just wanted to say that this quote is hilarious. I tried
               | to look it up, but couldn't find anything. What's it
               | from?
        
               | mumblemumble wrote:
               | Andrew Gelman, a semi-famous statistician. Author of some
               | good textbooks. I'm not sure of the original source, but
               | here's a list of chestnuts from his website: http://www.s
               | tat.columbia.edu/~gelman/book/gelman_quotes.pdf
        
               | gerbilly wrote:
               | > N=36
               | 
               | This is just a cheap shot.
               | 
               | I'd be more impressed if you demonstrated why the sample
               | size lacks the power to demonstrate an effect. (Use math
               | and show your work.)
               | 
               | Also, it's a common mistake to assume that if the sample
               | size were 3 million instead that the study would be more
               | 'valid.'
        
               | mumblemumble wrote:
               | > I'd be more impressed if you demonstrated why the
               | sample size lacks the power to demonstrate an effect.
               | 
               | Unless and until someone in this thread gets a copy of
               | the paper so we can find out the effect sizes involved,
               | we simply aren't able to objectively assess the study's
               | statistical power.
               | 
               | But even then, I'm perhaps more worried about the file
               | drawer effect. The type 1 error rate is fixed at 5%, n=36
               | studies are cheap, and p>.05 studies never get published.
               | And we're looking at exactly one paper here. As far as
               | I'm concerned, you can't have credibility without
               | replicability.
        
               | kmlevitt wrote:
               | It's not just about raw numbers though, you need to
               | consider the experimental design, which looks really
               | tight in this case.
               | 
               | It's a repeated measures study and from the looks of it
               | all subjects spent time in each of the four treatments +
               | control, so it's direct comparisons of the same people in
               | each condition. They used three separate measures.
               | Accounting for all that, they are working with something
               | like 540 data points, and the fact it's the same people
               | in each set is a nice little feature for direct
               | comparisons rather than a limitation. They even double
               | blinded everything. All of that has to count for
               | something.
        
               | hattmall wrote:
               | There's pharma companies worth over a billion dollars
               | based on studies with a smaller sample sizes so I don't
               | see N=36 as a deal breaker especially when there's very
               | little money incentive here.
        
               | regularfry wrote:
               | What you'd hope is that someone would use that result to
               | get funding for a bigger study. I've got a lot of
               | sympathy for the sceptical position, but you've got to
               | start somewhere.
        
               | p_j_w wrote:
               | >N=36
               | 
               | Since you seem so certain, I have to ask: have you done
               | the math to show that 36 isn't enough to tell you
               | anything in this case?
               | 
               | Depending on the effect size and probability
               | distributions involved, N=36 can give you a pretty
               | respectable picture. It's not good enough to be the final
               | word on the matter, but most papers aren't aiming to be
               | that, nor should they. It seems to me these researchers
               | were trying to scientifically test an idea that floats
               | around coffee communities (I've heard specifically that
               | theanine in your coffee will do this). There's no reason
               | to "go big" right away when doing such a study. You start
               | small to see if there's any hope for the idea, then try
               | to get funding for a larger study by publishing.
               | 
               | >4 servings over a short period of time
               | 
               | The definition of "a short period of time" is relative.
               | In this study, what you're defining as a short period of
               | time seems ludicrous. The participants were given the
               | servings on entirely different *days*, which is far past
               | the amount of time that caffeine or theanine are active.
               | 
               | Finally, the article on HN the other day about bad
               | research was not about small sample sizes, it was about
               | outright fraudulent data. It's certainly possible that
               | this study is a fraud, but, even if we grant that the
               | sample size is small and the delay between administration
               | is too short, that's not evidence of fraud.
        
               | [deleted]
        
             | bodhi_mind wrote:
             | https://twin.sci-
             | hub.se/6118/daefd0e8ce13e7983e15445a67e567a...
        
           | [deleted]
        
         | cipherzero wrote:
         | What was the article from yesterday? I feel like I missed
         | something helpful.
        
           | ChrisArchitect wrote:
           | https://news.ycombinator.com/item?id=27884233
        
         | derbOac wrote:
         | That's why I usually pay most attention to meta-analyses, if
         | the studies aren't huge and preregistered:
         | 
         | https://pubmed.ncbi.nlm.nih.gov/24946991/
         | 
         | That meta-analysis kinda suggests theanine doesn't really have
         | much effect; caffeine improves attention.
        
           | [deleted]
        
         | [deleted]
        
       | chalst wrote:
       | Couldn't fit title and date into 80 chars, so the story title is
       | edited:                    Caffeine and theanine exert opposite
       | effects on attention under emotional arousal, Grace E Giles et
       | al., Canadian Journal of Physiological Pharmacology, January
       | 2017.
        
         | 0xTJ wrote:
         | I'd call the current title of this post blatantly wrong. In
         | common use, "emotional arousal" and "arousal" have _very_
         | different meanings.
        
           | nkozyra wrote:
           | Agreed; in fact, it makes two points that have different
           | impact:
           | 
           | > Consumed together, caffeine and theanine exert similar
           | cognitive effects to that of caffeine alone, but exert
           | opposite effects on arousal, in that caffeine accentuates and
           | theanine mitigates physiological and felt stress responses.
           | 
           | This is inline with the anecdotal evidence about theanine's
           | mitigating effect on caffeine & stress.
        
             | benogorek wrote:
             | So is it fair to say that with tea relative to coffee, you
             | get all the cognitive benefits and none of the arousal
             | downsides (e.g, anxiety)?
        
               | whoisburbansky wrote:
               | In my experience it's been that tea gives me far less
               | anxiety, but still a nonzero amount. It doesn't wipe it
               | out entirely, but it reduces the physiological symptoms
               | of anxiety.
        
               | tracedddd wrote:
               | Not none. The downsides are moderately decreased in my
               | experience. I'm not sure the amount in tea, I suppose it
               | varies greatly, but I've tried several different
               | l-Theanine doses and caffeine mostly still feels like
               | caffeine, just slightly modified.
        
               | sunshineforever wrote:
               | In my experience, many of the negative effects are
               | greatly reduced. When my dad first brought back a box of
               | PG Tips from a work trip in London, I discovered I could
               | drink like, ten cups and still function. Only moderately
               | burned out.
               | 
               | If I had drank the same amount of coffee I'd've needed to
               | lay down. It was great for all nighters playing Halo
               | multiplayer.
               | 
               | All this time I thought tea's superiority was due to it
               | having "more hydration" or something. This is so
               | interesting to know!
        
           | sunshineforever wrote:
           | I understood "arousal" to be the emotional sort of arousal,
           | but I see your point.
        
           | [deleted]
        
           | TheFreim wrote:
           | Almost skipped an otherwise interesting topic because of
           | this.
        
           | chalst wrote:
           | I'm still able to edit the title: care to suggest another
           | version that fits within 80 chars? The title alone fits, one
           | char to spare, but I didn't want to pass off a 4-y.o. paper
           | as if it was pharmacological news.
        
             | xVedun wrote:
             | Possibly something like this: Caffeine and theanine have
             | opposed effect on attention when stressed (2017)
             | 
             | Based on the definition of emotional arousal, stress isn't
             | 100% accurate, but perhaps better than aroused.
             | 
             | [1] https://www.thefreedictionary.com/emotional+arousal
        
       | mkw2000 wrote:
       | I was taking theanine pills for a while and I definitely felt
       | like it had a positive impact on my overall mood
        
       | JohnWhigham wrote:
       | I've seen this in many places; people will take L-theanine to
       | counteract any jittery effects of caffeine, but I never noticed
       | anything. What L-theanine is helpful for is going to sleep and
       | calming one's mind.
        
         | srean wrote:
         | Indeed. When I am over-caffeinated I am energized but not
         | exactly effective. L-theanine centers my mind.
        
         | danielam wrote:
         | I have. I can drink green tea (including strong matcha), which
         | does contain l-theanine, probably daily, but I cannot drink
         | coffee daily for more than maybe 2 weeks without experiencing
         | adverse affects. Even one cup of coffee can leave me agitated.
         | Supplementing coffee with l-theanine completely eliminates
         | agitation.
        
           | fighterpilot wrote:
           | Black tea is also very high in l-theanine. Regular green tea
           | is not, but matcha (which you consume) is as well.
        
             | danielam wrote:
             | I can also drink black tea for longer durations than
             | unsupplemented coffee. When I drink green tea, my typical
             | choice is sencha, but it is not nearly as concentrated as
             | the matcha. So I suspect the caffeine is therefore lower
             | than my typical cup of coffee, hence the reduced agitation?
        
             | zamfi wrote:
             | > Regular green tea is not
             | 
             | Not...very high? Just "regular" high?
        
           | amelius wrote:
           | Can you drink cola without adverse effects?
           | 
           | Because I can. And coffee gives me issues after a week or
           | two.
           | 
           | Therefore something seems wrong about giving caffeine all the
           | blame.
        
             | [deleted]
        
             | danielam wrote:
             | I don't drink soft drinks generally, and certainly not in
             | those quantities, but I vaguely recall feeling anxious
             | after drinking cola before.
             | 
             | > Therefore something seems wrong about giving caffeine all
             | the blame.
             | 
             | Possibly, but in this case, my primary comparison is
             | between coffee and coffee with l-theanine and that one
             | difference by itself produces a very noticeable difference
             | in effect. I do not know what else in coffee could be
             | producing jitters other than the caffeine. Or what in the
             | cola could perhaps be inhibiting the effects of caffeine.
        
             | fighterpilot wrote:
             | > And coffee gives me issues after a week or two.
             | 
             | Have you tried drinking an equivalent amount of cola (in
             | terms of caffeine dosage) every day for a week or two?
        
               | amelius wrote:
               | Yes, I think so. I drank a lot of (diet) cola at some
               | point, like 1 gallon a day. Never got any issues similar
               | to the ones I got from coffee.
        
               | bagacrap wrote:
               | A gallon of diet coke has less caffeine than one
               | Starbucks venti drip coffee (~380mg vs ~400mg).
               | 
               | How much coffee do/did you drink per day?
        
               | amelius wrote:
               | Like 3-5 regular cups a day (not Starbucks). Then after
               | two weeks even 1 cup became too much. Switching to a
               | gallon of cola then didn't cause any problems.
        
         | tylermenezes wrote:
         | I am extremely sensitive to caffeine, it makes me super jittery
         | and I can feel my heart race.
         | 
         | For the last 4 years I've been adding 100mg of pure caffeine
         | powder and 125mg L-theanine to a non-caffinated morning
         | beverage. I even had someone secretly add or not add the
         | L-theanine without telling me for a while, so it's as well
         | controlled as an n=1 study can be.
         | 
         | The difference is pretty night-and-day for me, but obviously
         | ymmv.
         | 
         | There's a lot of genetic difference in caffeine processing, and
         | I happen to have almost every genetic variant associated with
         | high sensitivity I could find studied.
        
           | bserge wrote:
           | Taurine and GABA synergize similarly with caffeine.
        
         | deregulateMed wrote:
         | I wish caffeine made me feel anything.
         | 
         | I would need over 24 oz of coffee for anything.
         | 
         | But at that point I'm pushing potentially unsafe levels..
         | 
         | I wish we were taught more about taking drugs. Use caffeine
         | since it's legal, for an example.
         | 
         | "Don't have caffeine 2 days in a row. Ask yourself if you
         | really need the energy or are thirsty/bored. Etc...."
         | 
         | You could apply the same to alcohol to reduce alcoholism.
        
           | UI_at_80x24 wrote:
           | >I wish caffeine made me feel anything.
           | 
           | (intentionally NOT quoting the remainder of your post)
           | 
           | The only time I ever felt anything from caffine:
           | 
           | I was working the midnight shift. (At a service industry job,
           | there were no customers so it was dead.)
           | 
           | I took:                 2 caffeine pills       4 coffee's
           | 2 cans of coke
           | 
           | It worked. I was very jittery, and had the shakes. But I
           | survived the shift, and by the time the shift was over (7am)
           | the sun was up, and I had a 1 hour drive to get home.
           | 
           | I was also surprised to learn while driving Truck, that some
           | US States outlawed caffeine pills. (Ohio) It might have been
           | available at a drug store though, I only had access to truck
           | stops.
        
           | n8cpdx wrote:
           | You might have adhd. I fall into extremely high doses because
           | a high level of stimulant use is needed to get to a "normal"
           | baseline.
           | 
           | Of course tolerance is also a factor. I've been reducing my
           | intake, for a while it was well over 1g/day, and that wasn't
           | really about trying to "feel" anything.
        
       | pineconewarrior wrote:
       | Anecdotally, I have found l-theanine supplementation at night to
       | work very well for insomnia and restful sleep.
        
         | ianai wrote:
         | Same, though it does seem to make dreams more vivid. Probably
         | important to be careful of dosing. Less may be more.
        
           | ryeights wrote:
           | Source? If this is true, it would explain a lot for me!
        
             | ianai wrote:
             | JRE had someone on recently about neuroscience. He said he
             | cautions people against taking theanine for sleep if
             | they're prone to sleep walking.
        
         | eridan2 wrote:
         | which brand do you use?
        
           | pineconewarrior wrote:
           | I typically grab whatever is reasonably priced. Right now I
           | have the NOW branded 100mg capsules. I avoid the larger
           | dosages for reasons mentioned in sibling comments.
           | 
           | AFAIK it is not one of the supplements which requires careful
           | brand selection (like a magnesium supplement).
        
       | Clewza313 wrote:
       | Looks like Hong Kongers may be onto a good thing with yuenyeung,
       | the local blend of coffee and tea:
       | 
       | https://en.wikipedia.org/wiki/Yuenyeung
        
         | eternalban wrote:
         | "Tea is perceived as more relaxing than coffee, even though
         | both contain caffeine. L-theanine in tea may account for the
         | difference."
         | 
         | Tea already contains both substances. Adding coffee would only
         | up the caffeine levels + whatever else is in coffee. Unless I'm
         | misunderstanding the abstract, this seems to argue for only
         | drinking tea to get both the "cognitive effects" and the
         | calming effect of L-theanine.
        
           | p_j_w wrote:
           | Some people, myself included, prefer the taste of coffee,
           | though. So if I can just add some flavorless theanine and get
           | some nice cognitive effects out of the deal, that's great.
        
             | weird-eye-issue wrote:
             | You wouldn't mix tea in your coffee to do that. You would
             | just buy L-Theanine powder and mix it in. It's not
             | flavorless but due to the small quantity needed you
             | shouldn't taste it once mixed in your coffee
        
               | p_j_w wrote:
               | Sure, but the folks in HK might enjoy that particular
               | mix, right? I'm just trying to say that mixing in tea
               | with your coffee isn't pointless or run counter to this
               | particular study.
        
               | eternalban wrote:
               | Coffee has other side-effects. If you are trying to quit
               | smoking, for example, the task at hand will be far easier
               | if you do not drink coffee. Nicotine breaks down caffeine
               | and smokers who are coffee drinkers are subjected to
               | heightened agitation due to increased caffeine intake
               | when they stop smoking. Psychologically, this higher
               | level of agitation is misinterpreted as nicotine
               | cravings. It's a vicious circle.
               | 
               | Fair disclosure: I love the aroma of coffee and am a
               | coffee drinker and a smoker. They are like bad friends
               | for whom I have developed fond feelings.
        
               | ValentineC wrote:
               | Not just Hong Kong, but Singapore and Malaysia too. :)
               | 
               | It's also _much_ better with processed milk -- usually
               | condensed (lots of added sugar) [1] by default, or
               | evaporated (no added sugar) [2].
               | 
               | [1] https://en.wikipedia.org/wiki/Condensed_milk
               | 
               | [2] https://en.wikipedia.org/wiki/Evaporated_milk
        
       | marttt wrote:
       | Somewhat related: In his recent book "This is Your Mind on
       | Plants", Michael Pollan also discusses caffeine addiction.
       | Transcript of an interview with him on Tim Ferriss' blog:
       | 
       | https://tim.blog/2021/06/30/michael-pollan-this-is-your-mind...
       | 
       | I've been off caffeine and yerba mate (of which the yerba I
       | consumed daily for the past 9 or so years) for two weeks. Feels
       | really great, I admit being somewhat less sharp mentally (for
       | now), but I still get everything relevant done. And -- maybe yet
       | I feel kind of more... mentally balanced? Imagine having less
       | thoughts throughout the day, but the ones you have, you'll like
       | more. :)
       | 
       | It's like my energy levels are much more consistent, no sudden
       | drops throughout the day -- and that's even when I'm doing heavy
       | physical work. (I'm a full-time forestry worker, tree planter,
       | brush cutter these days -- now not even thinking about the usual
       | midday yerba mate kick I used to rely on.)
       | 
       | The tiredness that sets in at night also feels much more calming.
       | So IMO it's a highly recommended shift overall -- I guess just
       | the first 4-5-6-7 days without coffee/strong tea may be really
       | hard.
        
         | themodelplumber wrote:
         | Curious, do you use anything else? I like trying out various
         | ideas on long or difficult hikes. One category that
         | consistently helps is the anti-inflammatory category.
         | 
         | I've also tried some pretty interesting nootropics including
         | one that was designed to support work in extreme environments,
         | and the difference in feeling from caffeine was pretty wild. (I
         | did have some pretty fascinating but unwanted side effects
         | while getting the dosage dialed in, basically what I'd call
         | super soldier mode, so I hesitate to mention it by name...)
        
           | marttt wrote:
           | Nope, nothing else. I have been heavily relying on yerba mate
           | -- one sip or tiny cup works wonders during heavy tree
           | planting sessions. This has always been my secret weapon,
           | because, in contrast to coffee, it doesn't seem to cause a
           | feeling of fluid loss.
           | 
           | Also, during tree planting, I only occasionally eat a few
           | carrots or other vegetables to help me finish the day. After
           | that, a well-deserved meal will follow.
           | 
           | Disclaimer, though: I have experimented with intermittent
           | fasting for several years, so I suppose my body has already
           | adapted to long periods of hunger. Be careful with this
           | stuff, though, and don't listen to my silly advice.
        
           | actually_a_dog wrote:
           | I'm not sure if this is exactly what you're getting at, but,
           | in the anti-inflammatory category, glucosamine and aspirin
           | are both great, and have some pretty good science behind
           | them.
        
         | danenania wrote:
         | Do you think doing a job involving more physical than mental
         | labor made it easier to get through the withdrawal? It seems
         | like pushing through the stupor is tough but doable for
         | physical stuff, whereas with mental work (like programming) you
         | can be pretty much knocked out of commission until the symptoms
         | subside.
        
           | marttt wrote:
           | > Do you think doing a job involving more physical than
           | mental labor made it easier to get through the withdrawal?
           | 
           | Very probably, yes. IIRC, I have actually tried quitting
           | yerba/coffee a few times earlier as well while doing mostly
           | mental work. And I always failed. Currently my days in the
           | forest consist of several 1.5h brush cutting sessions --
           | meaning, during that time, I am in nonstop movement, cutting
           | the brush, unable to do anything else. During a break between
           | the sessions, I am usually heavily dehydrated, so my body
           | just wants a lot of water. I think I've even come to dislike
           | the idea of having coffee or (really surprisingly) yerba mate
           | at that point.
           | 
           | Currently I usually work 3x1.5h sessions every day, plus
           | water drinking breaks and saw blade sharpening, so it's
           | around 5-6 hours in the woods every day. And, in the forest
           | you have no coffee shops, no other shops, no fridges. And, if
           | you manage not to take coffee with you, there's simply no
           | coffee at all nearby! I suppose that's the essential part of
           | the whole trick.
           | 
           | I plan to return to mental work for the winter. I do think
           | staying off yerba/coffee will be a struggle again for indoor
           | work and/or cold season.
        
             | swader999 wrote:
             | Neat to hear from a planter, you guys are at the front of
             | the pack when it comes to maximising physical performance.
             | 
             | Are you working in BC right now?
        
           | amacneil wrote:
           | You don't have to quit caffeine cold turkey. You can just
           | ramp down from n cups of coffee/day to 1 cup, then switch to
           | n cups of tea/day (black or green) and ramp down to 1 cup,
           | then switch to low-caffeine or caffeine-free tea, then stop
           | entirely.
           | 
           | Have been off caffeine for several years now. Took probably a
           | couple months to reach a point where I felt comfortable going
           | into an interview or important meeting without it. Now I
           | don't miss it at all, but if I ever do have it, a cup of
           | decaf coffee will have me buzzing for hours, and an espresso
           | will make me extremely uncomfortable and jittery - crazy that
           | that used to be my baseline intake.
        
             | JohnBooty wrote:
             | Now I don't miss it at all, but if I ever do          have
             | it, a cup of decaf coffee will have me          buzzing for
             | hours, and an espresso will make          me extremely
             | uncomfortable and jittery
             | 
             | I think you're rather lucky! Whenever I successfully wean
             | myself away from caffeine... one reason I can never stay
             | away is because when I go back to it, it feels _so good._
             | 
             | However I feel lucky myself in a different way. Never been
             | tempted by harder drugs because caffeine has taught me I'd
             | never stand a chance against them lol.
        
               | amacneil wrote:
               | Addiction is real :)
        
           | JohnBooty wrote:
           | Not the person you asked but: absolutely yeah.
           | 
           | Coding and other such mental work is very tough for me unless
           | a lot of factors line up. But I can stay focused on physical
           | tasks even if I'm feeling like garbage - even something like
           | tennis that's both mental+physical.
           | 
           | edit: Are you talking about sudden "cold turkey" quitting +
           | the subsequent withdrawal? The answer to that is _hell no_ --
           | if I try anything that foolish I 'm really in for some hurt.
           | Luckily as others have noted, there's no need to experience
           | withdrawal if you taper dosage down over a week or two.
        
           | kossTKR wrote:
           | Exactly, i find mental work close to impossible a few days
           | after quitting caffeine. I can do social stuff to an extend
           | and get manual labor stuff done, but not anything requiring
           | initiative and self discipline.
        
         | navi0 wrote:
         | I'd be interested in talking with you about a project I'm
         | working on (forestry-related, not caffeine-related), if you're
         | open to it.
         | 
         | Info@madronus.com
        
       | Deutscher wrote:
       | Does anyone else suffer from GI issues like epigastric pain
       | (acidity) brought on by tea/coffee consumption? How do you deal
       | with it?
        
         | nikk1 wrote:
         | I have GERD and take esomeprazole daily. I used to take
         | omeprazole but it gave me headaches
        
         | DantesKite wrote:
         | I don't suffer GI issues because of coffee consumption, but I
         | do have GI issues that I'm currently resolving with Visbiome.
         | 
         | It's expensive, but it's really the only probiotic that has
         | ever made a difference for me.
         | 
         | My acid reflux is almost completely gone because of it.
        
           | paraph1n wrote:
           | Could you talk more about what your acid reflux was like? I'm
           | curious about finding new ways to treat my own. Been on
           | 20-40mg of (es)omeprazole daily for a decade.
        
         | abawany wrote:
         | For coffee, I've seen people recommend putting in a dash of
         | baking soda in the drink to reduce the acidity though I haven't
         | tried this. I also tried some of the low-acid coffees and they
         | were fine though the flavor is in no way comparable to my
         | favorite poison :). Drinking these beverages when you are not
         | expecting to recline (e.g. in the morning and early afternoon)
         | may also help.
         | 
         | However, if you feel these symptoms are pretty bad, it is worth
         | going to a gastroenterologist - chronic upper GI acidity can
         | lead to GERD and that can lead to esophageal cancer.
        
       | zug_zug wrote:
       | https://en.wikipedia.org/wiki/Theanine#Effects
        
       | taeric wrote:
       | Any recommendations on this self experiments to see how much
       | coffee does or does not affect you?
       | 
       | I ask because I don't get any high or rush from coffee, that I
       | notice. I would be interested in tracking signs looking for
       | impact. But I mostly just like the taste.
        
         | mumblemumble wrote:
         | I guess it depends on what you're looking for?
         | 
         | For a subtle effect like this, I would argue that it's not
         | actually possible to experiment on yourself in a meaningful
         | way. If you don't use a double blind protocol, then any real
         | effect is going to be completely overwhelmed by things like the
         | placebo effect. And the absolute minimum number of people
         | required to implement a double blind protocol is three: one to
         | assign treatment and analyze the data, another to administer
         | the treatment and collect the data, and one person to actually
         | get experimented on.
         | 
         | For this particular experiment, I'd go a step further and say
         | say that the absolute minimum is 4, because you want to make
         | sure that both alternatives are being tested under conditions
         | where it's the participant's first time performing the
         | cognitive task you're using for evaluation. That's only
         | possible if you have separate participants for the treatment
         | and control.
        
           | taeric wrote:
           | I was asking more in the general case for coffee.
           | 
           | I mean, I know basically how many beers will get me drunk and
           | am well aware of the times I drink. Coffee, though? I read
           | tons of folks saying it affects them... But it feels similar
           | to the folks saying vitamin d improved their life. I am not
           | claiming they are false, but I am claiming I don't feel it.
        
             | nick__m wrote:
             | It's hard to tell without knowing of strong your coffee is,
             | your pink grapefruit intake and most importantly your
             | sensitivity to caffeine.
        
             | mumblemumble wrote:
             | I don't have a source for this, but I've heard that coffee
             | legitimately does affect some people differently. Because
             | some people have a gene for an enzyme that metabolizes
             | caffeine very effectively, and others don't.
             | 
             | Which, that may not even be true. In which case, I don't
             | mind. It was all by way of illustrating, be careful trying
             | to extrapolate from a sample size of 1. In fact, just don't
             | do it. Conversely, don't assume an aggregate statistic
             | accurately describes anybody in particular.
        
               | taeric wrote:
               | Would love to read a bit more on that. If anyone has a
               | good source on variation of caffeine susceptibility, I'd
               | be grateful!
               | 
               | And the point on being careful extrapolating makes sense.
               | I will work on that.
        
               | nick__m wrote:
               | This will interest you "Interindividual Differences in
               | Caffeine Metabolism and Factors Driving Caffeine
               | Consumption" :
               | https://pharmrev.aspetjournals.org/content/70/2/384
        
         | hfjtntnfjfk wrote:
         | How's your sleep?
         | 
         | Once I stopped drinking caffeinated soda my sleep quality
         | improved massively. I was drinking it at least 8 hours before
         | sleep, but apparently caffeine works close to 12 hours.
        
           | taeric wrote:
           | Fine? I have apnea, so that dominates any sleep concerns I
           | have. But, I've never used an alarm clock in my life and I
           | can still reliably wake up on time every day.
        
         | [deleted]
        
         | tylermenezes wrote:
         | If you have a company you can ship it to, you can still buy
         | pure caffeine powder from bulk supplement retailers. (No one
         | will sell to individuals anymore because of the safety risk.)
         | 
         | That makes it a lot easier to meter dosage for an experiment.
         | You can also try to get consistent caffeine by using a
         | consistent, fresh bean/roast, high quality burr grinder, and a
         | brix meter to check extraction %.
        
           | taeric wrote:
           | I have little doubt that pure caffeine would impact me. My
           | question is on the rush from coffee. To me, it is just a
           | tasty drink. I don't feel more awake after it. At all.
        
       | Dragging-Syrup wrote:
       | 36 participants on metabolic processes study seems like a small
       | sample size
        
         | dylan604 wrote:
         | Not defending ridiculous claims based on small sample sets, but
         | isn't this how it's supposed to work? You run some tests and
         | notice a pattern and develop an hypothesis, and then continue
         | to expand the test to see if it holds true? Then other groups
         | perform the same tests to hopefully receive the same results so
         | that we end up with known facts. Essentially, the definition of
         | scientific method.
        
           | SantalBlush wrote:
           | Yeah, but people aren't actually that interested in the
           | scientific method here. Criticizing things is an easy way to
           | appear smart, and that's the main point.
           | 
           | Empirical research has never been about some true/false
           | binary; that's a myth perpetuated on HN. It has always been
           | about strength of evidence, improving models, and opening
           | paths for future research. I've seen people dismiss case
           | studies by decrying that their n=1, for god's sake.
        
       | nextlevelwizard wrote:
       | I've been mixin L-theanine to my office coffee for years. It
       | might be pure placebo, but I feel like I can concentrate better
       | with it.
        
         | DantesKite wrote:
         | How's the taste? Notice any huge changes?
        
           | mullen wrote:
           | Although slightly higher in cost, you can get Theanine in
           | pill form.
        
           | gqz wrote:
           | L-Theanine is somewhat sweet and... chalky, perhaps. It's a
           | little savory/funky too. Not altogether an unpleasant
           | flavour. I occasionally take a teaspoon of unpacked
           | L-Theanine powder and stir it into a glass of water. It
           | doesn't mix very readily, but once it does, it's barely
           | noticeable (at least to my palate). I don't notice it when I
           | repeat this process with green or black tea, so I would be
           | surprised if anyone could detect it in coffee.
        
       | cutthegrass2 wrote:
       | Articles mentioning caffeine and or theanine always remind me i'm
       | drinking too much coffee and need to cut down.
       | 
       | For what it's worth though, I certainly notice the effects of
       | theanine when I take it, usually 200mg upon waking before my
       | first coffee.
        
       | PaulHoule wrote:
       | The lady at the Korean grocery store seemed suspicious when I
       | bought the last tea set they had. (They hadn't sold one in
       | years.)
       | 
       | I think of it as a "high performance" teapot because I can heat
       | water in a kettle and use Sencha + Matcha to have delicious and
       | relaxing green tea in about 2 minutes and 30 seconds. I wash out
       | the metal filter and it's ready to go again.
        
       | Darmody wrote:
       | I've been taking tabs with 100mg of caffeine and 250mg of
       | l-theanine after lunch and I found it better than a large coffee.
        
         | ianai wrote:
         | Do you take anything for sleep?
        
           | Darmody wrote:
           | No. I've taken melatonin in the past and I don't know if it
           | worked or it was just placebo because I changed also some
           | habits like not going to bed with my tablet to watch Youtube.
           | After taking the pill I didn't stare at any screen and I kept
           | the lights as low as possible to help my body produce more
           | melatonin.
           | 
           | Some "rituals" before sleeping are helpful too, like turning
           | every thing off and drinking a cup of linden tea or valerian
           | tea and then going to bed. Even a rooibos or anything without
           | caffeine works, the important part is the ritual where you
           | relax and prepare your body for the night.
           | 
           | In addition to that I found out that a little bit of
           | intensive workout helps a lot. You don't need a 10km run or
           | to light weights for 2 hours. Just put some tension into your
           | body. You can't do a push up? Do half and stay there hanging
           | with some tension on your muscles. Stretch your body until
           | you feel the burn for a while, specially legs and back. There
           | are some yoga posses where you stretch and also use your
           | strength and they don't require any experience. And of
           | course, don't hurt yourself doing more than what your body
           | can take.
        
           | hammock wrote:
           | Theanine is supposed to help with sleep too
        
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