[HN Gopher] Mouse research identifies new types of neurons in th...
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       Mouse research identifies new types of neurons in the "gut brain"
       (2020)
        
       Author : truth_
       Score  : 60 points
       Date   : 2021-06-21 20:00 UTC (3 hours ago)
        
 (HTM) web link (www.popularmechanics.com)
 (TXT) w3m dump (www.popularmechanics.com)
        
       | cryptica wrote:
       | This gives new meaning to the phrases "I have a gut feeling" and
       | "Trust your gut."
        
       | UncleOxidant wrote:
       | Cool, then if they know how it works they'll be able to fix my
       | IBS, right?
       | 
       | I don't think they know how it works yet, nor did I read any
       | details in that article that would make me think that they had it
       | all figured out.
        
         | malexw wrote:
         | Has your health care practitioner suggested a probiotic of
         | lactobacillus plantarum (specifically Lp299v)? This study
         | published in February of 2021[1] suggests it can significantly
         | reduce symptoms when taken daily over a multi-month period.
         | Perhaps something to discuss with the doc if you haven't.
         | 
         | [1] https://pubmed.ncbi.nlm.nih.gov/33556972/
        
         | wayneftw wrote:
         | I changed my diet and my stress level. Eat at regular times,
         | learn to let go (it helps to see the big picture and remember
         | that you'll be dead before long) and add some probiotics to
         | your gut. Eating lots of Kimchi and Kombucha helped almost
         | immediately. I'm sure you can find lots of similar advice on
         | the web.
        
           | sharadov wrote:
           | Yoghurt is great too.
        
           | TedDoesntTalk wrote:
           | Try also Visbiome unflavored. 450 billion bacteria per
           | packet. It's expensive so I only take 1 packet per week.
        
       | yellow_lead wrote:
       | No, they still don't. I went to a GI doctor recently with the
       | complaint that I can't consume caffeine, or oily foods anymore
       | without stomach issues. He prescribed a GI antibiotic to "try."
       | Nothing has changed but I'm a bit poorer.
        
         | treeman79 wrote:
         | Oily food issue. Was having that. Ended up being pancreatitis,
         | which itself was an early symptom of autoimmune disease
        
         | dlsa wrote:
         | I'd go to a different doctor. Antibiotics always require a
         | reason involving something bacterial. There is no "try".
         | 
         | Example case in point: antibiotics can mess up a healthy person
         | and induce stomach issues.
        
           | treeman79 wrote:
           | I had a mystery illness. I kept a 4 page sheet of symptoms
           | and what helped hurt.
           | 
           | One doctor read though it and correctly diagnosed the mystery
           | illness. (Sjogrens) Later verified.
           | 
           | Turned out the line that caught his attention was that
           | symptoms always eased up when I took doxicyline. This 80 year
           | old doctor had seen that enough to pick out the illness.
           | 
           | There is some minimal research into the topic but in general
           | it's a taboo subject and no doctor will consider a round as a
           | test to see if it will help.
        
       | jschveibinz wrote:
       | Scientists: We are studying gut neurons.
       | 
       | Marketing: What are neurons?
       | 
       | Scientists: They are cells in our nervous systems, such as the
       | brain.
       | 
       | Marketing: guts have brains?
       | 
       | Scientists: well, I wouldn't...
       | 
       | Marketing: never mind, we got this...
        
         | rcxdude wrote:
         | The analogy is more apt than saying e.g. your leg has a brain
         | due to the nerves in it. The nervous system in the gut has a
         | lot of neurons in it (the human gut has about as many as a
         | cat's brain), and they are not just simple sensory or motor
         | neurons relaying information, many are at least similar to the
         | kind of 'decision-making' neurons you find in the brain.
        
           | meristem wrote:
           | I knew my gut liked lasers and catnip for a reason.
        
         | c7DJTLrn wrote:
         | It's not marketing, but clickbait media watering down science
         | that can't really be watered down.
        
       | stenl wrote:
       | Cool. Ulrika's office is across from mine, and this is a more
       | extensive follow-up of work we did together in 2018 to map neuron
       | types in the gut (and in the whole nervous system). I'm pretty
       | sure Ulrika wouldn't claim to know how the ENS works (nor do I)
       | but having the parts list is incredibly important. For example,
       | it enables genetic manipulation to delete cell types or activate
       | them on-demand using light. Those things are what will lead to
       | understanding how the system works.
        
       | [deleted]
        
       | nemo44x wrote:
       | How does this effect people who have had a full or partial
       | colectomy? Is this tied to the large, small, or both?
        
       | [deleted]
        
       | abnry wrote:
       | Just change the "hey" to "heyy there" to make the headline even
       | more ridiculous.
        
         | newsbinator wrote:
         | This headline needs a "lol" or a "rofl" appended for maximum
         | effect.
        
         | 2bitencryption wrote:
         | There's a Second Brain in your Gut and I can't even
        
       | metalman wrote:
       | Gut brain or enteric brain There are neural nodes throughout your
       | ,ya you,body. Bunch around your spine. And the ones around you
       | gut,that have the same number of neurons as a cat. That inner
       | voice is real baby.
        
       | [deleted]
        
       | thebean11 wrote:
       | no they don't
        
         | [deleted]
        
       | blakesterz wrote:
       | Is there some kind of "law of headlines" that states most
       | headlines dealing with breakthroughs in health always end with
       | "In Mice"? If not, there should be. This study shows how it
       | works... in mice:
       | 
       | https://www.nature.com/articles/s41593-020-00736-x
       | 
       | I'm not trying to dismiss things, just seems important to note
       | this is from work done on mice, not people.
       | 
       | "Hey, There's a Second Brain in Your Gut And now scientists know
       | how it works In Mice" still sounds ok to me.
        
         | dang wrote:
         | We've attempted to replaced that wretched title with something
         | serviceable. The entire article is dreadful, including what
         | they've done with links, but I wasn't able to find a better
         | third-party source.
        
         | _Microft wrote:
         | That's a common problem and there's even a Twitter account
         | dedicated to calling that out:
         | 
         | https://mobile.twitter.com/justsaysinmice
        
         | yorwba wrote:
         | Even that doesn't seem to be accurate:
         | 
         |  _"Using extensive co-staining with established markers, they
         | were able to relate the twelve neuron classes to previously
         | discovered molecular characteristics of functional enteric
         | neuron types, thus classifying the ENCs into excitatory and
         | inhibitory motor neurons, interneurons, and intrinsic primary
         | afferent neurons."_
         | 
         |  _With a sharper protocol and new information, the researchers
         | were able to confirm and expand on the existing body of ENS
         | neuron knowledge. And now they can work on finding out what
         | each of the 12 ENS neuron types is responsible for, they say._
         | 
         | Which sounds less like "now scientists know how it works in
         | mice" and more like "now scientists know more about the
         | different cell types it contains in mice."
        
         | allturtles wrote:
         | As long as we're complaining about the title, can I register my
         | dislike of the pointless "Hey,"? I guess this is supposed to
         | make science reporting seem more casual and approachable?
        
           | avaldes wrote:
           | "Your gut has a brain... AND THATS A GOOD THING"
        
           | jl6 wrote:
           | No, it's an "engagement hack" to increase clickthrough rates.
        
           | frogpelt wrote:
           | I want to complain too. I found this sentence in the article:
           | "The gut brain greatly affects on how you body works."
           | 
           | I have trouble reading articles with obvious errors in them.
           | The writer probably gets paid very little and I doubt there's
           | an editor. But I expect more, I guess.
        
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       (page generated 2021-06-21 23:02 UTC)