[HN Gopher] Urine test can detect brain tumors with 100% accuracy
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       Urine test can detect brain tumors with 100% accuracy
        
       Author : giantg2
       Score  : 38 points
       Date   : 2021-06-18 19:38 UTC (3 hours ago)
        
 (HTM) web link (www.yahoo.com)
 (TXT) w3m dump (www.yahoo.com)
        
       | giantg2 wrote:
       | I found this interesting. My wife was recently diagnosed (via
       | another method).
        
       | MattGaiser wrote:
       | How is it that we don't have a toilet unit test runner of sorts
       | yet?
       | 
       | Why can't I pee and have my pee tested every time I use my
       | toilet?
        
         | dragonwriter wrote:
         | That's more of an acceptance test than a unit test.
         | 
         | Also, https://med.stanford.edu/news/all-news/2020/04/smart-
         | toilet-...
        
       | antipaul wrote:
       | I dunno, N=66 training and N=34 for validation along with Lasso
       | regression suggests the performance measures are dramatically
       | overfit
       | 
       | See figure 3 etc:
       | https://pubs.acs.org/doi/pdf/10.1021/acsami.1c01754
        
       | et2o wrote:
       | This is nearly certain to be oversold. The etiology and
       | composition of brain tumors is highly diverse; they don't all
       | share the same biology and the study design here (100 "CNS
       | tumors" vs. "normal" individuals) leaves a lot to be desired.
       | It's not clear to me if they also are basically using the same
       | testing and training dataset or not.
       | 
       | Even the headline here (100% accuracy) is inaccurate; it had 100%
       | sensitivity). The list of cancer bio markers which have turned
       | out not to work for screening is quite extensive.
       | 
       | That said, the most interesting thing here is the microRNA
       | capture technology. If it can be scaled, it might be interesting.
        
         | EMM_386 wrote:
         | > If it can be scaled, it might be interesting.
         | 
         | The article seems to indicate it can.
         | 
         | "It can be sterilized, produced on massive scales and completed
         | by patients any time anywhere with "minimal effort," according
         | to the study published recently in the journal ACS Applied
         | Materials & Interfaces."
        
         | gus_massa wrote:
         | Also:
         | 
         | > _A urine test developed by researchers at the Nagoya
         | University in Japan can pinpoint a person who has a brain tumor
         | -- regardless of its size or malignancy -- with 100% accuracy,
         | according to a new study._
         | 
         | They used samples of pee of people that were diagnosed with CNS
         | tumors with other methods, so my guess is that they had already
         | big enough tumors to cause problems, so " _regardless of its
         | size or malignancy_ " is probably too optimistic.
        
       | jollybean wrote:
       | Your toilet will become your doctor in the next 20 years. It will
       | be able to tell more about you than Google or your Doctor. It
       | will become the source of 'early prediction' of everything.
       | 
       | Sounds kinda funny but I'm not joking.
        
         | doggodaddo78 wrote:
         | Exactly what I was thinking. Cancers, metabolic & endocrine
         | disorders, GI microbiome, pregnancy testing, STI testing, and
         | so forth. I don't know how test consumables would be made with
         | longevity, but there's likely clever approaches to make it
         | work.
         | 
         | Surreptitious drug testing the kids too.
         | 
         | Just be worried about holographic ads suggesting baby carriages
         | or suppositories.
        
         | tmabraham wrote:
         | A recent paper on this:
         | https://www.nature.com/articles/s41551-020-0534-9
        
         | gruez wrote:
         | Reminds me of a skit from adultswim:
         | https://www.youtube.com/watch?v=DJklHwoYgBQ
        
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       (page generated 2021-06-18 23:02 UTC)