[HN Gopher] Cancer has ripple effect on distant tissues
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       Cancer has ripple effect on distant tissues
        
       Author : gmays
       Score  : 27 points
       Date   : 2021-05-14 19:17 UTC (3 hours ago)
        
 (HTM) web link (source.wustl.edu)
 (TXT) w3m dump (source.wustl.edu)
        
       | tyingq wrote:
       | There's also the separate effect on distant tissues from
       | radiation, chemo, and surgery. Gastrointestinal surgery, for
       | example, can have pretty disruptive effects that aren't really
       | related to cancer directly.
        
         | hluska wrote:
         | This is a poignant reminder of something awful a close relative
         | said to me while she was undergoing cancer treatments. She
         | talked about how she had an aggressive form of cancer, surgery,
         | chemo and radiation. Between the four, she never knew whether
         | something was a symptom of getting worse, a side effect of
         | treatment or just one of the weird things that bodies do. The
         | part I still find troubling is that she said that after a
         | certain point, she realized her doctors weren't sure either.
        
       | autojoechen wrote:
       | The article seems to be talking about two potentially unrelated
       | effects - up-regulation of gluconeogenesis in the liver and
       | BCAT1. The gluconeogenesis makes sense in the presence of
       | glucose-hungry cells, the body would start making its own to
       | stabilize blood sugar. I wonder what the signal mechanism is for
       | the BCAT1 up-regulation?
        
         | agumonkey wrote:
         | talking about glucose and tumors, anybody knows some good reads
         | about benefits of ketogenic or similarly low sugar diets in
         | regards to cancer ?
        
           | bawolff wrote:
           | If you pick your reading based on the answer you want to
           | hear, you're only going to ever get confirmation bias.
        
             | agumonkey wrote:
             | I'm not thank you
        
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