[HN Gopher] Setting the record straight: There is no 'Covid heart'
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       Setting the record straight: There is no 'Covid heart'
        
       Author : AndrewBissell
       Score  : 50 points
       Date   : 2021-05-14 19:11 UTC (3 hours ago)
        
 (HTM) web link (www.statnews.com)
 (TXT) w3m dump (www.statnews.com)
        
       | ergljlkjsrth wrote:
       | More conspiracy theories from the Branch Covidian camp of
       | lunatics debunked again and again.
        
       | kleton wrote:
       | Is covid still a vascular disease, or does this new study
       | negatively replicate this study?
       | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556303/
        
         | graeme wrote:
         | No that article is about injury to the epithelial system (in
         | the blood vessels) whereas the article is about the claims that
         | covid damaged the heart itself more than other viruses.
         | 
         | I am not sure if anyone has done before/after studied of
         | epithelial function in covid patients.
        
       | renewiltord wrote:
       | There was a lot of breathless nonsense from a bunch of people
       | about this disease. I just Bayes low-weighted it because the
       | prior probability is low. So far a whole bunch of these things
       | are coming back non-replicable. It'll be an interesting test of
       | each of our epistemological techniques.
       | 
       | My prior to start with is high that the contagiousness-increasing
       | mutation (the novel spike protein) improves likelihood of the
       | virus attacking more organs and improves its ability to massively
       | infect the organ but that once you've got a massive infection of
       | the organ, you should see effects after recovery that are similar
       | to any other such infection of the organ.
       | 
       | I'm actually curious if anyone has neat software that tracks
       | one's predictions and allows one to adjust their knowledge of the
       | world systematically. Currently only using a shared spreadsheet
       | with friends.
        
         | DubiousPusher wrote:
         | For sure. The media tends to report science press releases
         | fairly uncritically. The result is that science reporting is
         | reporting of claims of scientists and not of "science" itself.
         | A better media ecosystem would incorporate the fact that many
         | preliminary findings never pan out.
        
           | renewiltord wrote:
           | I'm quite curious if there is a group of like-minded
           | individuals out there who would participate in a wiki that
           | attempts to summarize (with degree of certainty) the current
           | known knowledge.
           | 
           | The general Internet has a tendency to consider individual
           | papers authoritative summaries of the general state of a
           | field. And single studies rarely have that predictive power.
           | For instance, one might read a single paper about a single
           | study that says "Doubling of rectal cancer risk occurs if red
           | meat is consumed right after sugar intake", and most Internet
           | commentary will attempt to show this as incontrovertible
           | truth. However, few such studies actually last or survive
           | replication.
           | 
           | i.e. most Internet commentary over-weights single study
           | results, with near binary probability of truth measures:
           | either something is almost certain or almost never.
           | 
           | Would prefer a place where I can discuss with people who are
           | less stridently enthusiastic about these papers, and where
           | long membership retains historical prediction performance (I
           | don't mind people disregarding my future predictions if my
           | current predictions are poor) with appropriate windowing to
           | permit learning.
        
             | _fs wrote:
             | > I'm quite curious if there is a group of like-minded
             | individuals out there who would participate in a wiki that
             | attempts to summarize (with degree of certainty) the
             | current known knowledge.
             | 
             | Yes, it can be found at a http://wikipedia.org
        
               | renewiltord wrote:
               | I'm actually a long-term contributor to Wikipedia (in my
               | 14th year) and, as you can imagine, therefore a huge fan.
               | However, Wikipedia does not attempt a synthesis of
               | knowledge, preferring to be a repeater of what is
               | publicly currently believed to be knowledge.
               | 
               | i.e. if CNN, the WSJ, and the NYT report X is Y, that
               | will count a lot more about X being Y than X actually
               | being Y.
               | 
               | Wikipedia is a wonderful resource and it definitely
               | partly scratches this itch, and I appreciate your sharing
               | it, but I am looking for something that occupies a
               | slightly different space.
        
           | makomk wrote:
           | As I recall, the media applied plenty of scrutiny to any
           | claim that Covid might be less deadly than the media coverage
           | suggested, the breathless uncritical reporting lent almost
           | entirely in one direction.
        
             | krrrh wrote:
             | Important to clarify that much of scrutiny went in the
             | other direction, cutting down concerns about how bad things
             | could get in January and February of 2020.
        
               | mikem170 wrote:
               | After that I still saw a pattern where the media kept
               | proffering worst case scenarios at every step, with no
               | studies to back them up, even contradicting known
               | science.
               | 
               | The most recent example of this is fear-mongering
               | headlines indicating that the vaccines would not be
               | effective against variants. This might be expected
               | behaviour for the flu, but not a coronavirus.
        
         | stevenhuang wrote:
         | Bayesian reasoning has its limits.
         | 
         | > "The man who has fed the chicken every day throughout its
         | life at last wrings its neck instead, showing that more refined
         | views as to the uniformity of nature would have been useful to
         | the chicken" - Bertrand Russel
        
         | totalZero wrote:
         | I can't think of a past novel disease that didn't stir up
         | fearful misinformation. Yet I also remind you that every
         | disease has a different pathology. It is worthwhile to report
         | anecdotal clinical presentations because that reporting spurs
         | research. The research can then corroborate or controvert the
         | reports.
         | 
         | A lot of what you suggested is kind of silly. Contagiousness is
         | not the same thing as virulence or pathogenicity, and you can
         | look at things like the common cold (contagious but mild)
         | versus ebola (harder to transmit but severe) to disprove the
         | proposition in your second paragraph.
         | 
         | The fact of the matter is that some people have not recovered
         | after a long time ("long covid") and that clinical observation
         | needs to be researched and explained before we brush off
         | concerns about organ damage as "breathless nonsense." Some
         | suggestions may be wrong but that doesn't mean their study is
         | not useful. Every time we disprove a concern, we come closer to
         | a full understanding of a disease that has affected people all
         | over the globe.
        
           | renewiltord wrote:
           | > _A lot of what you suggested is kind of silly.
           | Contagiousness is not the same thing as virulence or
           | pathogenicity, and you can look at things like the common
           | cold (contagious but mild) versus ebola (harder to transmit
           | but severe) to disprove the proposition in your second
           | paragraph._
           | 
           | This is actually related to the stuff I'm referring to in my
           | cousin comment. Existence proofs are not evidence of certain
           | behaviour. An analogous situation might be "If you see a car
           | slow down approaching a pedestrian crossing with a Stop sign
           | it is likely to stop". Most pedestrians will consider this
           | statement true (as evinced by how they behave - placing
           | themselves in range of bodily harm). However, many
           | pedestrians know that at least one car has not behaved in
           | this manner. Responding to someone who agrees with that
           | statement with "Cars certainly do blow through stop signs
           | even if they're slowing down. Here are some news articles of
           | that happening" only marginally moves the evidence-o-meter.
           | 
           | Some things need empirical understanding. "Related counter-
           | examples" do not set the likelihood of the statement to zero,
           | but only downgrade it somewhat.
           | 
           | Personally, I've found my performance on COVID predictions
           | pretty decent. My biggest failure was that I believed outdoor
           | masking was necessary, and it currently looks like that is
           | not the case.
           | 
           | We shall see if Long COVID is any sort of true long-term
           | disease that is particularly unique or merely the
           | identification of other symptoms that previously went
           | untested simply because most illnesses go untested.
           | 
           | And of course I have no problem with anyone sounding small
           | alarms on small studies. A sufficient number of independent
           | such instances is how we identify common patterns. I,
           | obviously, weight each individual such instance low but
           | corroboration increases likelihood. Still, we'll see.
           | Currently, my method of acquiring knowledge outperforms
           | public CDC statements about the disease1, so I'm at least
           | better at this than they are.
           | 
           | 1 Assuming, perhaps naively, that they prioritize
           | dissemination of truth over public health objectives that may
           | temporarily be better met through carefully told untruths.
        
             | wizzwizz4 wrote:
             | Humans aren't ideal Bayesian rational agents, and even
             | _they_ are susceptible to selective reporting. I don 't
             | think this comment is useful.
        
               | renewiltord wrote:
               | Oh we most certainly aren't. And I frequently make errors
               | as well, but I aspire to be better at this than I am and
               | I think I'd enjoy the company of others like this.
        
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