[HN Gopher] Sleep deprivation impairs molecular clearance from t...
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       Sleep deprivation impairs molecular clearance from the human brain
        
       Author : lame-robot-hoax
       Score  : 19 points
       Date   : 2021-04-21 19:30 UTC (3 hours ago)
        
 (HTM) web link (academic.oup.com)
 (TXT) w3m dump (academic.oup.com)
        
       | pedalpete wrote:
       | There has been a strong correlation that the build up of amyloid
       | plaques is tied to degenerative brain diseases. I think the
       | expectation has always been that this is a build up over time,
       | and that one all-nighter or a few isn't harmful. Like eating
       | fries, your body will repair itself as long as you don't make it
       | a habit.
       | 
       | This study suggests that the brain does not remove these built up
       | paque over a 4 week period. I'd be very interested to see if the
       | researchers are able to do a further follow-up study, but this is
       | very damning evidence of the importance of quality
       | sleep...always!
       | 
       | My startup (https://soundmind.co) is working on using sound to
       | improve sleep quality, and our DeepWave stimulation is
       | specifically targeting the processes which clear the amyloid
       | plaques discussed in the paper. There is great research regarding
       | improving the capabilities of the brain to clear plaque in a
       | reduced time frame by increasing the power and number of waves in
       | a slow-wave oscillation.
       | 
       | I had been under the assumption that this meant we would be able
       | to repair previous damage to a certain percent. Unfortunately,
       | this appears not to be the case.
       | 
       | As a life-long insomniac who witnessed an uncle die from
       | Alzheimer's, I'm very concerned of the effects.
       | 
       | Please take care of your sleep. I'm working to help you, but
       | until we're able to do it, and prove that we can do it, just
       | don't damage yourself.
        
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       (page generated 2021-04-21 23:01 UTC)