[HN Gopher] Haplotype linked with lower incidence of severe Covi...
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       Haplotype linked with lower incidence of severe Covid inherited
       from Neandertals
        
       Author : Hooke
       Score  : 31 points
       Date   : 2021-02-17 16:50 UTC (1 days ago)
        
 (HTM) web link (www.pnas.org)
 (TXT) w3m dump (www.pnas.org)
        
       | retox wrote:
       | Directly contradicts a story from 5 months ago:
       | https://news.ycombinator.com/item?id=24637337
       | 
       | That story
       | 
       | >A study published in Nature shows that a segment of DNA that
       | causes their carriers to have an up to three times higher risk of
       | developing severe COVID-19 is inherited from Neandertals. The
       | study was conducted by researchers at Karolinska Institutet and
       | Max Planck Institute for Evolutionary Anthropology.
       | 
       | This story
       | 
       | >We show that a haplotype on chromosome 12, which is associated
       | with a ~22% reduction in relative risk of becoming severely ill
       | with COVID-19 when infected by SARS-CoV-2, is inherited from
       | Neandertals. This haplotype is present at substantial frequencies
       | in all regions of the world outside Africa. The genomic region
       | where this haplotype occurs encodes proteins that are important
       | during infections with RNA viruses.
        
       | pella wrote:
       | COVID-19 related SNP-s:
       | 
       | https://www.snpedia.com/index.php?title=+Special%3ASearch&se...
        
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       (page generated 2021-02-18 23:02 UTC)