[HN Gopher] Microbial ecosystems in the mouth and gut are linked...
___________________________________________________________________
Microbial ecosystems in the mouth and gut are linked to many ills
Author : aluket
Score : 128 points
Date : 2021-02-12 19:11 UTC (3 hours ago)
(HTM) web link (www.economist.com)
(TXT) w3m dump (www.economist.com)
| arminiusreturns wrote:
| I had the pleasure to work with a top geneticist whose domain of
| specialty was the microbiome, and he continually insisted there
| are tons of discoveries to be made in the arena (which he and
| those researchers we sequenced for did often, from dentistry to
| studies of the monitor lizard to chrons disease, just all over in
| subjects you might not expect).
|
| Less on topic, I learned how to read scientific papers and filter
| bullshit ones (even in respectable journals) from good ones under
| his tutelage, and am forever grateful to the vast array of
| science and tech I was exposed to while supporting the tech side
| of a "every major sequencer" sequencing lab.
| domino24 wrote:
| Who did you work for? I am interested in getting more involved
| in this exact field and would appreciate any helpful direction
| :) I am digesting anything I can find on the topic, but I feel
| it is greatly underappreciated still, as I agree there is MUCH
| to be discovered.
| pazimzadeh wrote:
| > Dr Sampson has tested this hypothesis in mice. He bred a strain
| of E. coli that cannot make Curli and injected mice with it,
| while injecting others with unmodified bacteria. Those that
| received Curli-producing bacteria expressed higher levels of
| synuclein and demonstrated symptoms like involuntary rigidity
| which, when seen in people, are associated with Parkinson's
| disease. That is tantalising.
|
| These mice were mono-colonized with E. coli, whereas both mice
| and humans normally have a diverse gut flora. I colonize mice
| with E. coli containing curli all the time and the mice do not
| exhibit any rigidity or symptoms of Parkinson's. So it's
| interesting but not quite as huge of an effect as you might
| think, unless your microbial flora is really disrupted. May be
| relevant if you have an antibiotic resistant strain of E. coli
| blooming in your intestine following antibiotic treatment/some
| other disruption of your microbiota.
|
| A gut bacterial amyloid promotes a-synuclein aggregation and
| motor impairment in mice
| https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012599/
| boplicity wrote:
| As someone with IBD, I really wish the hard science about
| bacteria would start to filter into actual treatments. I know
| there are possibilities there, and many patients have found
| avenues of success, but there is so much guesswork involved
| that it is very frustrating. Hopefully there will be definitive
| answers in the future. My gastroenterologist, who has quite a
| lot of training from very good schools, has absolutely nothing
| useful to say, in terms of the microbiome.
| throw345hn wrote:
| As someone with IBS, totally agree with you. I wish the
| research would trickle down into actual treatments. I have
| started following a lot of research about gut etc but very
| little of it leads to something that can mass consumed.
|
| I spent thousands of dollars on trying out medications,
| tests, visiting a number of highly trained doctors etc,
| nothing came up in tests and at the end almost all doctors
| threw their hands up and categorized my gut issues as IBS
| which is just a catchAll term for which there is no specific
| treatment other than trying out a number of things.
| newobj wrote:
| Excited for more research in gut health.
|
| I know HN hates to entertain any lay science, but I wonder if
| scraping my tongue, as I do with a copper scraper, is good or bad
| for your oral biome?
| eth0up wrote:
| Below is an interesting bit of research which gets quite close
| to tackling your curiosity, or at least stimulating it. It
| specifically concerns oral hygiene and blood pressure, with a
| focus on nitric oxide. Tongue scraping seems beneficial, though
| there's no mention of copper. However, chlorhexidine (mouthwash
| ingredient) seems a disruptor of NO and may contribute to
| higher BP. I need to read the article myself, but a brief skim
| left a big impression.
|
| https://pubmed.ncbi.nlm.nih.gov/33066082/
| abledon wrote:
| in the morning, even scraping with your hand is good since
| you're removing the dead stuff thats accumulated on your tongue
| during sleep. eating this stuff has no nutritional value and is
| considered a 'toxin' in yogic traditions.
|
| lot of those online sites are just trying to 'sell something'
| to make a living so they mandate you 'need' a metallic scraper.
| StavrosK wrote:
| Probably!
| recuter wrote:
| Indubitably!
| sherr wrote:
| Dentists (ones I have) usually recommend brushing your tongue
| as part of your tooth brushing routine. This helps prevent bad
| breath I think, which is correlated with oral hygiene.
| DNied wrote:
| PAYWALLED
| echelon wrote:
| As a layman, this is so exciting! It feels as though we may be
| getting closer to finding a cause for a diverse set of
| neurodegenerative disorders. Alzheimer's, Parkinson's, etc.
|
| Gut and oral microbiota having influence across the blood-brain
| barrier seems so plausible. If they get into the nervous system
| and migrate, they could cause inflammation in the brain leading
| to damage over time.
|
| The immune system is incredible, and we'll no doubt find it a
| fertile ground for progress against a lot of diseases.
| wyldfire wrote:
| Do we know whether these microbes are cause or effect? On the
| bright side I'd say even if they're [only] an effect of those
| illnesses, we'd have an excellent opportunity for earlier
| diagnosis.
| bsanr2 wrote:
| Adding to the anecdotes:
|
| Around summer 2014, I began to focus very heavily on "bulking"
| for strength training. This was about a year after I'd developed
| very obvious symptoms of lactose intolerance and had had to cut
| uncultured dairy out of my diet. My meals were not diverse: fruit
| and Greek yogurt in the morning; chicken cooked in Indian sauces,
| roasted potatoes, and some green (usually broccoli or spinach)
| for lunch and dinner, along with protein shakes and a pre-workout
| carb load (such as PB+J). Drinks were water, orange juice, and
| kefir.
|
| That winter, my health collapsed. I started developing skin
| abscesses, and the antibiotics I received for a particularly bad
| episode caused me to develop a C diff infection. I had to
| severely limit my food intake, as too much or certain kinds would
| cause me to develop cramps, listlessness, and diarrhea, and lost
| about 40 pounds in 3 months. My body could not hold onto food
| long enough to process it correctly and I developed symptoms of
| incomplete digestion, and especially of fat indigestion (symptoms
| improved with anti-diarrheals).
|
| The next 3 years were a long battle to try to get back to normal.
| Store-bought probiotics didn't help; digestive enzymes did.
| Things didn't improve noticeably until after I began eating
| homemade sauerkraut, and especially after I began taking enzymes
| on an empty stomach (I was told that this might help to break
| down some structure that might harbor unhelpful bacteria).
|
| Eventually, I was able to return to most foods without issue,
| until last year, when a prediabetes scare prompted to try a
| ketogenic diet (this also seemed to solve a lingering issue, of
| multiple daily and urgent movements).
|
| All this to say... I don't really know what's going on. I've
| found some things that seem to work, but I could only guess at
| why, based on the timing of my downturns and upturns and of my
| interventions.
|
| I've spent literal days over this period trying to understand why
| my body is acting and reacting the way that it does, and
| following the (often slapdash) advice of people who target the
| microbiome as the source of ill or good health has sadly seemed
| to be the most efficacious route. However, I'm still not able to
| achieve the level of well-being I'd like to, and I attribute that
| largely to the dearth of hard facts available relating to diet
| and the human microbiome. Over the course of this journey, I've
| seen more and more professionals begin to take the issue
| seriously, but not nearly the level or quality of research we'd
| hope to see with such a fundamental topic. Here's to seeing that
| corrected before I have to punch whatever card this adulthood of
| gut trouble has been leading to.
| inamberclad wrote:
| Seems like a good plug for a startup I used to work for. I'm no
| longer associated with them aside from my personal friendships
| but they're creating a pretty cool oral health product:
| https://freshhealth.com/
| andrewzah wrote:
| This is something that I've been thinking about lately.
|
| Last ~May, I spontaneously developed rashes exactly in the middle
| of the back of my hands at the same time. This lead to skin
| sensitivity and ultimately skin rashes across my body.
|
| At this point I've visited my dermatologist what, 20 times? In
| addition to my general physician, bloodwork, etc. Biopsies and
| bloodwork and other tests don't show anything abnormal, asides
| from excessively high IgE - 600 and now about 1,000. I recently
| started on Dupixent but it's too early to tell if it's helping or
| not.
|
| There doesn't seem to be any clear indicator, so I'm wondering if
| I ate something + stress, which affected my gut microbiome. My
| family has no history of this sort of issue and it seriously
| started about overnight.
| rusabd wrote:
| Are you losing weight? I had some rash appeared spontaneously
| after start losing weight and it took almost a year to clear
| out
| tnayrb wrote:
| I'm no expert, but something similar happened to me a few years
| back. The conclusion was an allergic reaction to the sun...
| andrewzah wrote:
| Did it go away on its own?
| aedocw wrote:
| I can't confirm today because it's very overcast, but as of
| a few days ago the sun had still not gone away.
| nerdponx wrote:
| There's almost never harm in trying an elimination diet. Cycle
| out one major food at a time (eg wheat, eggs, milk, meat,
| nightshades, seafood), for a couple weeks at a time.
|
| Maybe start gradually introducing fermented "live" foods as a
| matter of routine.
|
| Worst that happens is you eat more veggies and try out a
| different diet. And if you find something that helps, all the
| better.
|
| It's pretty well known now that skin conditions can be related
| to gut conditions.
| airstrike wrote:
| For what it's worth (very little, since it's a medical anecdote
| shared online), my wife had a nasty case of hives for the first
| time in her life after trying a sarecycline treatment. Took us
| quite a while to connect the dots, though, and to this day we
| don't know if it was really what caused it (or stress, or the
| fact that she took 3 different vaccines on the same day, or
| everything combined)
|
| All of that is to suggest that you think about what you have
| changed about your diet, medication or anything else either in
| May or shortly before that
| andrewzah wrote:
| > what you have changed about your diet, medication or
| anything else either in May or shortly before that
|
| Well, there are only 2 things I can think of. Firstly, due to
| covid I had been working at home from March to May. Before
| covid I would still go out a lot to cafes/social workspaces
| and get sunlight. And around mid-march I started running. By
| May I was running about 5k-7k daily throughout my
| neighborhood.
|
| So we initially thought it was a bug related thing, but
| everything came back clean. We tried eliminating food, but
| nothing really seemed to have an effect after a week or two.
|
| I spoke to my immunologist and he believes it's not food
| related as I already have food related allergies (peanuts),
| so eating something else should give me quick reactions like
| peanuts do. Also, he said it's rare for adults to
| spontaneously develop something like that. Bloodwork has been
| inconclusive because my IgE is so high that it's causing
| false positives. I did a diff of my allergy bloodwork from
| and back in October, and multiple values did increase.
|
| I have tried basically everything- getting more sunlight,
| using sensitive detergent (3 different brands), cutting out
| coffee/gluten etc. Hell, we even replaced the carpet in my
| parents house with hardwood, and once I moved into my house
| we cut out the carpet as well.
| michael1999 wrote:
| Tick borne disease?
| rriepe wrote:
| Check out Dr. John Sarno's works. It's mostly about back
| pain but he covers other manifestations of the condition he
| calls TMS. He talks about a personality type which you seem
| to fit.
| wwww4all wrote:
| Mouth and gut health are directly related to physical health AND
| mental health.
|
| The gut is often called the second brain, and lots of mental
| health issues like anxiety, depression, stress, etc can be
| greatly helped by improving diet and healthy gut.
|
| It's criminal that medical establishments are controlled by
| pharmaceutical companies and establishment media spreads
| prescription drug propaganda.
|
| Everyone needs to do their own research about gut health and
| direct impacts to physical and mental health.
| tomrod wrote:
| > The gut is often called the second brain, and lots of mental
| health issues like anxiety, depression, stress, etc can be
| greatly helped by improving diet and healthy gut.
|
| Who calls it that? I've seen a comment or two before, but
| certainly not "everyone" calling it that. It's a nice analogy
| that probably could be stretched way too far, as these things
| go.
|
| Are the causal links clearly _known_ or correlation shows that
| the link may be identifiable?
|
| > It's criminal that medical establishments are controlled by
| pharmaceutical companies and establishment media spreads
| prescription drug propaganda.
|
| Hmm... this sounds like conspiratorial thinking. Do you have
| evidence of this, and if it is the case, a reason why this
| status quo is worse than other alternatives?
|
| > Everyone needs to do their own research about gut health and
| direct impacts to physical and mental health.
|
| Why? Wouldn't it be more reasonable for scientists to research,
| work towards consensus, then report findings, rather than
| duplicating the fixed costs of setting up laboratories and
| health testing facilities in our garages? Considering I did
| this, what is the likelihood I find a stronger connection or
| novel fact about certain microbiota that inhabit my or my
| families' bodies? Or perhaps you're being less precise in your
| terminology, and you're advocating that people study
| scientists' research rather than conducting wetlab studies.
| Could you clarify?
|
| Analogously, we should also all study the universe, but few
| advocate for all to build radio telescopes on their available
| rooftops.
| chiefalchemist wrote:
| > Hmm... this sounds like conspiratorial thinking.
|
| Does it? Why so? There are a handful of entities with control
| and they all tend to have the same mindset. There's no need
| for a conspiracy. Their context and objectives are the same.
| There are a limited number of paths to that goal. They will -
| like starlings - naturally "sync." No conspiracy necessary.
|
| The fact of the matter is, more and more "traditional
| medicine" that was long dismissed is proving to be healthy.
| The use of hallucinogens to treat mental health come to mind.
| How does Big Pharma deliver value to share holders with
| plants that most anyone to grow?
|
| Editorial: You sound naive, and likely a Big Pharma employee.
| [deleted]
| bserge wrote:
| Or many ills affect the body in more extensive ways than thought.
| Constipation could be an early warning sign of Parkinson's and
| other problems, for example, not that you'd be able to tell.
|
| I'm pretty "natural", never had antibiotics and stuff. But I can
| tell you I've got plenty of problems that can _never_ be fixed by
| gut bacteria.
|
| Besides, modern lives are anything but natural.
| vmception wrote:
| Interestingly, this is what holistic practitioners and
| naturopaths have been trying to say for a long time
|
| They've just substituted the scientific method with no method at
| all and devoid of all peer review or capability of it
|
| As technology improves I expect individualized and therefore
| holistic treatments to be at the forefront
| tempestn wrote:
| It really seems like some decades in the future we'll look back
| at the results of gut microbiome research as akin to the
| discoveries of bacteria and viruses. Before those discoveries it
| was known that people got sick, and that developing sickness was
| correlated with various things, like proximity to sick people, or
| poor hygiene, but the mechanisms behind those correlations
| weren't known. (Or they were suspected, but with some
| misconceptions or lack of detail.)
|
| I expect and certainly hope that as this system is better
| understood, it will unlock numerous significant advances in
| medical science. Would just be nice if that process could happen
| faster!
| forgotmypw17 wrote:
| A long time ago, our ancestors were single-celled.
|
| Then, some cells decided to live together, form a slime, division
| of labor, organs, etc. And today, voila, we have humans.
|
| However, the single-celled never went away. We have been living
| together, co-evolving together, all this time.
|
| No human has ever lived without a microbiome. We have been in
| symbiosis all this time. The immune system picks off the baddies,
| while the goodies get to stick around, serving all sorts of
| useful functions. Not only that, but the goodies actually edge
| out the baddies, because they consume most of the resources
| available to microbes. Combined with help from immune system
| police, a balance is reached.
|
| That's the way it works until you introduce various ways to harm
| the microbiome. Preservatives in the food. Substances which
| indiscriminately kill bacteria on the skin and elsewhere.
| Antibiotics. Then the balance is thrown off, the baddies get to
| proliferate unchecked, the immune system can no longer cope with
| their scale.
|
| I've stopped using any products which harm my microbiome. It's
| not easy, and it's not a one-day or one-month or one-year
| transition, but it's paid off in ways I didn't even imagine
| possible when I started out.
|
| Edit: When I post about this stuff, I often get asked about
| specifics. For reasons of privacy, and several others, I would
| rather not get into them. Do your own research, find your own
| way. Don't wait for everything to be handed to you on a plate.
| I've provided more than enough information in this comment.
| colordrops wrote:
| If you aren't willing to post specifics about your own
| activities, you could at least provide references for the
| statements you did make, e.g. battle to consume resources, and
| throwing the microbiome off.
|
| Don't bother to make vague generalizations without being
| willing to back them up, especially anonymously. It makes the
| statement nearly information-free. And this is coming from
| someone who agrees with your assessment.
| madaxe_again wrote:
| My wife had terrible acne for years - she tried every product
| under the sun, visited dermatologists, all of it.
|
| About nine months ago I persuaded her to try absolutely
| nothing. Just wash her face with mild soap and water when she
| showers or after exercise. It was a hard sell. A really hard
| sell. It looked sinfully angry for the first few weeks, and
| then, bit by bit, started to fade.
|
| Now... her skin is perfect, the scars are subsiding, and she
| hasn't had even a hint of acne or so much as a zit in four
| months.
|
| The crux of my hypothesis was that she was eradicating her skin
| microbiome over and over, and possibly breeding incredibly
| resistant bacteria with no competition.
|
| I take a similar approach with oral hygiene - I don't brush, I
| don't use toothpaste or mouthwash, I just use a wooden
| toothpick to get anything stuck out. I started this in my teens
| at boarding school, as toothbrushes were often "borrowed" for
| cleaning rugby boots, and then replaced in the rack. At the
| time, I figured not brushing was better than god only knows
| what being rubbed into my gums. I had _appalling_ breath and
| swollen gums for several months - but both just disappeared
| after adaptation.
|
| I go to see a dentist every few years, mostly out of a sense of
| obligation, and have never had a carie, cavity, periodontal
| disease, or anything - I'm pushing 40. The most they've ever
| done is polish them. By my age my mother had lost half her
| molars, my father had a gobful of crowns and fillings, so it's
| not genetics.
|
| Maybe I'm talking crap, but I think we significantly
| underestimate our bodies abilities to maintain themselves, and
| buy into the idea that we require products to keep them
| working.
|
| Unfortunately, weaning yourself off this stuff usually involves
| some degree of disruption, be it honking breath, or skin so
| angry you don't want to be seen in public.
| kart23 wrote:
| I've heard that some people do indeed have better bacterial
| biomes than others, some will be fine without brushing or
| flossing, and others will have problems. Saliva has a large
| part to play in preventing caries and bad breath, dry mouth
| can cause a lot of the issues you describe. Also, water
| fluoridation has made quite a big impact in public dental
| health. Remember that most people used to lose teeth
| regularly before the advent of fluoride toothpaste, often
| very early in their lives. Do you think that these people's
| teeth were maintaining themselves? Looking at old WW2 videos
| made me realize this, where many soldiers in their 20s had
| completely black teeth or massive gaps.
|
| https://en.wikipedia.org/wiki/Water_fluoridation#History
| accounted wrote:
| A similar, and perhaps better option:
| https://en.wikipedia.org/wiki/Miswak
| bserge wrote:
| Yeah, I'd say don't apply that thinking to _everything_.
| titzer wrote:
| Did you have your wisdom teeth out? Are your teeth straight?
| That makes a huge difference.
| da_big_ghey wrote:
| For what it's worth, I've done the same, but it only worked
| because I wasn't eating a bunch of sugary garbage. Definitely
| nobody should try it who eats that sort of stuff even
| somewhat often.
| pengaru wrote:
| Exactly.
|
| A close friend of mine had horrible dental hygiene, rarely
| brushing, drank soda and beer as his water, and only went
| to the dentist after developing intolerable pain something
| like a decade into this mode.
|
| When he came to work the day after his dentist visit, he
| said the dentist told him "this is what we call mountain
| dew mouth" when examining his teeth.
|
| If you don't eat stuff that makes plaque thrive, the
| consequences of ignoring it are less severe.
| Grimm1 wrote:
| You lost me at antibiotics. Overuse is a problem for certain,
| but we'd have a lot more death, and possibly worse, disability
| without them.
| serverholic wrote:
| You just made up an argument for a point that the OP wasn't
| making.
| Xunjin wrote:
| He is not wrong... OP did not make this point however you
| can infer it, from his point of view
|
| Actually in my limited knowledge about biology, both are
| right, when things are way discompensated, you have to use
| things to kill bacterias which almost take control of a
| part of your body (the baddies one) .
| croes wrote:
| Is it that why now more people live on earth than ever since?
| titzer wrote:
| Probably because of reduced all-cause mortality, increased
| food production, and the relative peace of the 20th century.
| azinman2 wrote:
| Relative peace of the 20th century? At least 108M have died
| in war. I believe it to be one of the biggest on record,
| and certainly not one of the peaceful times. So relative
| peace compared to what?
| zabzonk wrote:
| > So relative peace compared to what?
|
| Total world population.
|
| https://www.vox.com/2015/6/23/8832311/war-
| casualties-600-yea...
| RankingMember wrote:
| > Edit: When I post about this stuff, I often get asked about
| specifics. For reasons of privacy, and several others, I would
| rather not get into them. Do your own research, find your own
| way. Don't wait for everything to be handed to you on a plate.
| I've provided more than enough information in this comment.
|
| Come on now, are you really going to post about how something
| "paid off in ways I didn't even imagine possible when I started
| out" and not name even one example? This lowers your comment to
| being basically on the same tier of conversation as conspiracy
| theorists who brush off requests for proof with "DO YOUR
| RESEARCH, THE TRUTH IS OUT THERE I CAN'T GIVE YOU SPECIFICS".
| johnchristopher wrote:
| Haha, that's what he did :D.
|
| Coincidentally I looked at op's profile and found this URL
| again http://hn:hn@sHiTMyseLf.com/index.html. I had stunmbled
| upon it in a previous thread (don't remember which one, but I
| only look at profile when I read some specific kind of
| comments).
|
| I didn't get what the website was about last time and I
| didn't spend time enough this time either.
| forgotmypw17 wrote:
| That URL was obfuscated to prevent bot abuse.
|
| It will now be replaced with a new one.
| trhway wrote:
| unfortunately mentioning any specifics risks transforming the
| conversation into arguing about such a specific item with the
| results being projected back onto the main statement. It also
| risks sounding like one is pushing his/her pseudoscientific
| stuff. In the area like microbiome with highly individual
| situations and relatively low level of established science
| any specifics is just an anecdote not much suitable for
| rigorous discussion. (i have myself found a couple ways of
| dealing with my SIBO (test based diagnosed by GE) for example
| and almost never discuss those specifics. It is really an
| area of "do you own research" and the useful methods/etc. are
| really "out there".)
| johnchristopher wrote:
| Maybe so but "Don't wait for everything to be handed to you
| on a plate. I've provided more than enough information in
| this comment." is really condescending and not inspiring
| much trust.
|
| It's also a classic move when you can't backup your claims.
| bsanr2 wrote:
| "This worked for me, but might not work for you, because of
| our specific circumstances," followed by a detailed
| description, would suffice, and in turn be much less
| useless and condescending.
|
| Please, discuss specifics (as I have).
| M5x7wI3CmbEem10 wrote:
| how did you start?
| Diederich wrote:
| Starting in around 2013 or so, I stopped using any kind of
| soap or cleaner on my body, with a couple of exceptions. I
| still wash my hands regularly, and I use a tiny little bit of
| fairly bland, unscented soap between my legs in the shower.
| Note that my head hair is quite long, naturally coming down
| to my mid/lower back.
|
| How do I get my body/face clean in the shower? Very hot water
| and very vigorous scrubbing/rubbing.
|
| After doing that for a week, my body odor virtually
| disappeared, even when I was hot and sweaty. While my overall
| skin and hair condition had always been ok, it improved
| noticeably.
|
| I did this after reading a number of articles online about it
| and figured it would be worth trying.
|
| As a bit of an experimental control, I didn't tell my wife
| that I was doing this. We do regularly brush and braid each
| other's hair. After about two weeks, she said that my hair
| was more full and healthy than it's ever been, and she also
| confirmed the body odor changes.
|
| So this is anecdotal: it was useful for me, and might be
| useful to some others. However, given everything we're
| learning about microbiomes in _and on_ the body, it seems to
| make a lot of sense.
| jimlikeslimes wrote:
| Tried this for months, I really smelled bad. Good friends
| telling me unprompted etc. YMMV.
| pengaru wrote:
| I concur.
|
| I've lived in homesteading environments where numerous
| people go months bathing sparingly using just water,
| while still actually getting things done involving
| significant labor, sweating and generally getting dirty.
|
| Everyone reeks in these conditions. They don't realize
| it, and their intimate partners who are in constant
| contact also don't quite appreciate the degree of odor,
| because it's shared.
|
| But from an outsider perspective, it's _ripe_.
|
| There's probably an evolutionary reason for this, members
| of a tribe will smell similarly when eating the same food
| and sharing space/objects in close quarters. I can easily
| imagine how that would be advantageous. Foreigners will
| stink.
| Diederich wrote:
| > bathing sparingly
|
| That could be a difference; I scrub a good long time
| using quite a bit of hot water.
| sharadov wrote:
| I used to use hot water + scrub. Was told it's terrible
| for your skin by my dermatologist, you start developing
| eczema in some cases in the long run. Warm water, white
| unscented mild soap and no scrub was his recommendation.
| forgotmypw17 wrote:
| .
| volkk wrote:
| can you expand on that? and also what do you mean by ways
| you couldn't even imagine?
| refurb wrote:
| Knowing that what you eat - more fiber, less fiber, more carbs,
| less carbs, etc, how do you optimize your microbiome when there
| is so much variety among humans? Which is the right biome?
| atian wrote:
| You can start at blood type.
| dragosmocrii wrote:
| It's interesting to see more and more articles lately reporting a
| strong connection between ilnesses (or lack) and one's microbiome
| health. What I noticed from my experience, is that kombucha and
| kimchi make me feel great if I consume these regularly (once or
| twice a week). Sometimes I will indulge in some crap food like
| pizzas and noodles, which make me feel unwell, but kombucha and
| kimchi work as a reset :)
| andrebotelho wrote:
| solid read
| dekken_ wrote:
| https://outline.com/TtrWGF
| bigmattystyles wrote:
| Completely anecdotal, personal experience. It wasn't Accutane but
| when I was a pimply teen, in an effort to remedy the acne, I was
| prescribed doxycycline and another topical antibacterial
| ointment; in any case, I never had heartburn or experienced
| depression prior to that but a few months after starting those
| meds, both started. It's likely unrelated but whenever I read how
| crucial biomes are - I can't help but wonder. For the record, I
| preferred the acne.
| gr1zzlybe4r wrote:
| Anecdotally I wonder about this sometimes too. I took Accutane
| mostly because I had a parent that really drove me to take it
| (I think projecting some of their own issues with acne onto my
| completely normal amount of teenage acne) and I definitely feel
| like it changed my mood during and after taking it. I didn't
| drink at all on it either. It's a drug that you shouldn't be
| able to have a teenager take unless it's approved by a panel of
| dermatologists or something. I had no idea of the severity of
| the side effects from it when I took it.
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