[HN Gopher] Patient Regains Sight Following Artificial Cornea Im...
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       Patient Regains Sight Following Artificial Cornea Implantation
        
       Author : muskminion
       Score  : 377 points
       Date   : 2021-01-18 13:10 UTC (9 hours ago)
        
 (HTM) web link (www.prnewswire.com)
 (TXT) w3m dump (www.prnewswire.com)
        
       | unix_fan wrote:
       | In my opinion, the problem with technology that can help the
       | blind see is the lack of a profit incentive, which means you can
       | only buy from a few established players and no innovation is
       | encouraged, while prices remain astronomical. As it stands, I
       | already pay a lot more for products I need, especially since I
       | don't have any government assistance. It's what I like to call
       | the "blind tax". not everyone can afford to pay it. As such, it's
       | better to wait for general consumer devices with accessibility
       | features like the iPhone, which is far more affordable than a
       | braille note taker, for example. The potential market that could
       | afford something like this, is pretty small.
       | 
       | I hope technology like this eventually becomes available for
       | those of us living in developing countries.
        
         | User23 wrote:
         | A good example of this is the absolutely exorbitant prices
         | charged for low vision CCTVs and similar equipment. I assume
         | this is because the sellers are mainly targeting state aid
         | agencies so they can get those juicy tax funds.
        
           | dbcurtis wrote:
           | I suspect it is more just volume and support costs. There
           | really isn't much government financial support at all for the
           | vision impaired, outside of the Veteran's Administration
           | system.
           | 
           | A friend and I looked at doing a tech product for the vision
           | impaired. The business case just didn't pencil out, mainly
           | because of TAM.
        
         | ROARosen wrote:
         | I didn't see anything about pricing, are you referring to this
         | specific item or in general?
        
           | zdragnar wrote:
           | Not op, but it is true in general.
           | 
           | The challenge is volume; with a small market, there isn't
           | much motivation to struggle to stay in business selling at
           | low margins. Also, since these may be considered
           | accessibility devices but not medical devices, insurance May
           | not cover a lot of things that ought to be considered
           | essential.
        
             | markvdb wrote:
             | The profit motive is everywhere in the medical sector, and
             | that is a bad thing. Even if you believe in free markets,
             | it's not easy to get the best care.
             | 
             | To stay cose to the eye as a subject, look at vitreomacular
             | adhesion. Roughly two possible treatments: - costly and
             | complicated eye surgery - substantially simpler ocriplasmin
             | [0] injections
             | 
             | In many cases where ocriplasmin looks like it could be the
             | perfect solution, it isn't even considered. Could that have
             | something to do with the surgeon's incentives alignment?
             | 
             | [0] https://en.wikipedia.org/wiki/Ocriplasmin
        
               | ghufran_syed wrote:
               | An analogous problem in drugs seems to have been
               | effectively addressed by the Orphan Drug act
               | (https://en.m.wikipedia.org/wiki/Orphan_Drug_Act_of_1983)
               | 
               | Sounds like maybe there needs to be something similar for
               | medical devices?
        
             | salawat wrote:
             | This is the issue with most small population medical
             | research, or research that's worthwhile but by policy
             | difficult to commercialize.
             | 
             | "Sucks to be you" tends to be every non-sufferer's
             | response.
        
         | mschuster91 wrote:
         | > It's what I like to call the "blind tax". not everyone can
         | afford to pay it.
         | 
         | The other thing is that devices sold as "medical devices",
         | unlike "general consumer devices" have (for good reasons)
         | pretty strict regulatory schemes across the world, which means
         | that their development and maintenance costs _a lot_ more
         | money.
        
         | ausbah wrote:
         | the related term with drug development is "orphan drug". drugs
         | designed to treat rare medical conditions that are not
         | developed due to lack of profit incentive
        
       | tomglynch wrote:
       | The astroturfing in this thread is INSANE!!! Awesome. Inspiring.
        
         | TaupeRanger wrote:
         | Wait what? How do you come to that conclusion?
        
           | dang wrote:
           | There were a bunch of comments in this thread (now killed, so
           | you'd have to switch 'showdead' to 'yes' in your pforile to
           | see them) which looked suspiciously promotional and similar
           | to one another.
        
       | bambam24 wrote:
       | I'm keratakonus patient who needs such surgery as well, to
       | clarify there is also cornea transplant operations too. Which is
       | from a donor. But that surgery requires 6-12month healing time,
       | because it have many stiches
        
       | EvanAnderson wrote:
       | Keratoconus sufferer here. This looks really cool. I'm probably
       | not going to _need_ a corneal transplant at this point (since my
       | condition appears to have stabilized with age) but I 'm
       | definitely going to follow this. Even with correction the acuity
       | in one of my eyes is very bad (like, can't read 16 point font at
       | arm's length bad). Since this method takes the tissue rejection
       | concern out of the equation I wonder if an "elective" corneal
       | transplant might be an option down the road.
        
         | interestica wrote:
         | Also a Keratoconus sufferer. And it also looks like the
         | progression has at least stabilized with age (which makes
         | treatments like CXL kinda useless). What are you using for
         | correction? I ask because my _bad_ eye (which can 't get close
         | to correction with glasses) now gets _better_ than 20 /20
         | vision with hybrid lenses. And my _good_ eye can 't get the
         | same acuity! It's an interesting sphere of research (so much is
         | still unknown, and there are so many changes in the material
         | science aspects of it). I got by for a long time with
         | "extended-range" toric soft lenses and have very different
         | experiences depending on the material type. (For instance,
         | Frequency 55 XR was made with 'Methafilcon B' 'High Water
         | Ionic' and I had 'unexpectedly good vision' with them.)
         | 
         | Oh, contact lens material is a rabbit hole:
         | 
         | https://en.wikipedia.org/wiki/List_of_soft_contact_lens_mate...
        
           | EvanAnderson wrote:
           | I'm really pretty lucky. I can get by only using spectacles.
           | My prescription isn't really too bad. I can get acceptable
           | correction in my good eye and still have passable 3D vision
           | with correction in my bad eye. On that basis I've opted to
           | stay w/ spectacles. (I can get markedly better correction for
           | my bad eye with some more axial tilt. I tend to easily lose
           | convergence with that additional tilt and get massive
           | headaches, however.)
           | 
           | I tried soft contact lenses, prior to my keratoconus
           | diagnosis, when I was much younger. The foreign body
           | sensation simply would not go away. It was a massive
           | distraction, to the point that I couldn't really think about
           | much else. Then I start fidgeting with my eyes and end up
           | with swelling and tears. (Hard, balled-up fist eye rubbing
           | from severe childhood allergies is probably the root cause of
           | my keratoconus. The animal allergies are mostly gone now, and
           | the hay fever is only a mild irritation. I can still,
           | however, induce foreign body sensation and massive itchiness
           | just by touching the skin around my eyes. There's probably a
           | bit of obsessive compulsive disorder going on there.)
        
         | robin_reala wrote:
         | Honestly, I think CXL then laser surgery is probably a
         | preferable treatment to corneal transplants. You're looking at
         | 6 month recovery time for that.
        
           | slhck wrote:
           | Post-CXL laser surgery is not always possible. If the
           | cornea's thickness has already degraded too much, lasering
           | would be very risky and lead to tearing.
        
           | interestica wrote:
           | CXL isn't useful at all since his vision has stabilized. CXL
           | only halts the progression of the disease.
        
             | EvanAnderson wrote:
             | That's the assumption I've been led to believe by my doctor
             | as well. Doing some searching does show that there's been
             | some discussion of refractive surgery post-CXL, but I can't
             | imagine that putting any more stress on my baggy, distended
             | corneas would be a great idea. >smile<
             | 
             | I'm a little bummed I missed the possibility of CXL. I was
             | diagnosed with KC in 2004, at age 27. I saw a couple
             | specialists at the time, one of whom mentioned trials (in
             | the US, where I am) for a procedure to strengthen and
             | stabilize the cornea using UV light and riboflavin. He felt
             | it was too new and unproven to recommend I explore it.
        
               | robin_reala wrote:
               | I was offered the CXL / laser surgery combo by my
               | opthamologist (UK) 6 or 7 years ago, but decided to do
               | neither. Like you, my diagnosis has stabilised with age
               | (first diagnosed 1994) and I don't want to potentially
               | disturb it.
        
       | zerop wrote:
       | Why this small sized country has been so innovating so much? I
       | heard about them a lot.
        
         | fastball wrote:
         | Probably for the same reason that despite persecution all over
         | the world, Jewish people have generally been fairly successful
         | - good work ethic + strong sense of community + cooperation
         | within that community.
         | 
         | Or it's because they really are Yahweh's chosen people. That
         | would probably help things along.
         | 
         | I've leave it as an exercise for the reader to decide which is
         | more likely.
        
       | madspindel wrote:
       | > The blind receive sight, the lame walk, those who have leprosy
       | are cleansed, the deaf hear, the dead are raised, and the good
       | news is proclaimed to the poor.
       | 
       | Love reading news like this!
        
       | sam_goody wrote:
       | Awesome. Moving. Inspiring.
       | 
       | There are all sorts of headlines about one technology or another
       | that seems to never get beyond the lab.
       | 
       | How long have we been waiting for some way to regrow the tooth
       | after a cavity?
       | 
       | But then suddenly there is something like this. A PATIENT
       | ACTUALLY REGAINED SIGHT after years of total blindness.
       | 
       | That cannot be said with enough awe to do it justice. It brings
       | new faith to those at the forefront of medicine.
       | 
       | Anyways, for the docs in this and every other groundbreaking
       | attempt.... Thanks! No, really, Thank you with all my heart!
        
         | joaomacp wrote:
         | It's really amazing. I don't want to be the usual cynic HNer
         | talking stuff down, because this seems really groundbreaking.
         | 
         | However, corneal transplants are already a thing, and "Within
         | the United States, the supply of corneas is sufficient to meet
         | the demand for surgery and research purposes."
         | 
         | https://en.wikipedia.org/wiki/Corneal_transplantation
         | 
         | Of course a synthetic cornea seems like a more scalable
         | solution, and probably reduces costs in the long term, so this
         | is great progress.
        
           | throwaway4220 wrote:
           | I echo this sentiment. Here are the eligibility criteria:
           | https://clinicaltrials.gov/ct2/show/NCT04485858. I am not an
           | opthalmologist, however, it appears this is an option when a
           | transplant fails or is not indicated due to infection. It's
           | still excellent news!
           | 
           | Here's a good info page on corneal blindness
           | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823104/ warning
           | made me a bit queasy
        
           | waihtis wrote:
           | You're not being cynical, this is exactly what one should
           | expect in HN - combing through the deeper facts and not just
           | the superficial information.
        
             | Cthulhu_ wrote:
             | One thing that honestly puts me off of some HN threads is
             | the breathless "it's full of stars" comments where people
             | take one press release and their minds go to some near-
             | future utopia where everything is perfect and nothing
             | hurts.
        
           | voiprodrigo wrote:
           | It is true that corneal transplantation is a thing since
           | decades. However, a corneal transplant, like any transplant,
           | has its issues. Rejections can still occur, and the healing
           | process takes a long time, usually not less than one year,
           | involving constant adjustments. If a cost-effective synthetic
           | inert material addresses these issues, this is immense
           | progress.
        
             | gus_massa wrote:
             | But the GGP says
             | 
             | >>> _How long have we been waiting for some way to regrow
             | the tooth after a cavity?_
             | 
             | An artificial cornea probably solves a lot of problem with
             | rejections, but it is somewhat like filing the cavities in
             | the teeth with whatever paste they are using.
        
             | blincoln wrote:
             | I've read about people getting cataract surgery and ending
             | up with UV sensitivity due to the material some older
             | synthetic implants were made from, so I always assumed
             | artificial corneas weren't uncommon.[1] I've actually kind
             | of hoped I could get them some day.
             | 
             | Is the difference here that previous implants weren't total
             | replacements, or something else?
             | 
             | [1] e.g. https://www.komar.org/faq/colorado-cataract-
             | surgery-crystale...
        
         | zelphirkalt wrote:
         | Bloody marvelous!
        
         | melling wrote:
         | Yeah, regrowing teeth has been in the news for decades.
         | 
         | Treating cataracts with eye drops is one I noticed a few years
         | ago.
         | 
         | https://www.sciencemag.org/news/2015/07/eye-drops-could-diss...
         | 
         | I was surprised to find these start forming after age 40.
         | 
         | It's great when a little science fiction finally works.
        
       | silentsea90 wrote:
       | If I had helped get this built, I would die a happy man. Congrats
       | to all involved. This is inspiring!
        
         | gus_massa wrote:
         | From this article [1], there are (at least) other three
         | business building similar things. Perhaps you can apply to work
         | in any of them.
         | 
         | [1] https://eyewiki.aao.org/Boston_Keratoprosthesis_(KPro)
         | 
         | > _In recent decades multiple synthetic corneas have been
         | pioneered and developed, though only three are principally used
         | in practice: the Boston Keratoprosthesis (Massachusetts Eye &
         | Ear Infirmary, Boston, MA), the AlphaCor (Addition Technology
         | Inc., Des Plaines, IL) and the osteo-odonto keratoprosthesis
         | also known as the 'OOKP' (originally described by Strampelli,
         | modified by Falcinelli)._
        
       | gdebel wrote:
       | Corneal surgeon here ! (Note : I never implanted a
       | keratoprosthesis. This is an extremely unfrequent procedure,
       | usually performed by a handful of surgeons in a given country).
       | Some insights about this topic. This looks like a great device
       | (never heard before !). This is a keratoprosthesis, meaning this
       | is a last recourse, "no-hope-except-maybe-that", procedure.
       | However it looks infinitely more simple and respectful of the eye
       | integrity than current keratoprosthesis, and, if it really acts
       | like a scaffold for native corneal cells and allows a
       | colonization and the obtention of a satisfying corneal surface,
       | it could be a game changer. It is way too soon to know.
       | 
       | A significant percentage (I would say around 40-70%, depending on
       | the country) of corneal graft indications originates from
       | pathologies coming from the inner layer of the cornea (corneal
       | endothelium). Posterior lamellar graft (DMEK) allows today to
       | change only the thin cellular layer which is pathological, with
       | an usually quick recovery. Even the best performing
       | keratoprosthesis won't replace this procedure, because we care to
       | preserve the eye's integrity as much as we can.
       | 
       | It is interesting to remember that corneal transplantation is a
       | very special topic because the cornea is not vascularized,
       | meaning less rejection. There still is, of course, but the
       | outcomes as usually good. Keratoprosthesis are today indicated
       | when previous grafts where rejected, when the other structures of
       | the eye are healthy, and when the vision is extremely low. This
       | allows to gain a few years of very low vision before, usually,
       | losing the eye due to infection or high ocular pressure.
       | 
       | The technology presented has the potential: - to replace current
       | keratoprosthesis and lower the threshold to decide to perform the
       | procedure : yes, almost sure if the device is well-tolerated - to
       | replace perforating keratoplasty (full corneal replacement,
       | unfrequent today) where the cornea is damaged in its entirety:
       | maybe, highly uncertain for the moment. That would be an
       | incredible step forward, a revolution in our practice. - to
       | replace anterior lamellar keratoplasty, where the anterior wall
       | of the cornea is replaced : highly unlikely - to replace
       | posterior lamellar keratoplasty, where the cornea lacks
       | transparency because of inner layer cellular dysfunction: almost
       | impossible.
       | 
       | I would also like to raise awareness on the topic of eye rubbing.
       | The eye surgeon community progressively discovers the highly
       | harmful consequences of vigorous and daily eye rubbing. A few
       | teams (mine, notably) even think that it is the single trigger
       | for keratoconus. You will find a nice illustrations of what a
       | rubbed eye looks like in MRI I by googling "don't rub your eye"
       | (this is me in the MRI ;-) and more explanations here :
       | https://defeatkeratoconus.com/
        
         | loceng wrote:
         | I'm curious if you're familiar with the stromal stem cell
         | research for regenerating deeper corneal tissues?
         | 
         | Research from University of Pittsburgh, successful on mice/rat
         | models, was taken to India for human clinical trials with
         | pretty great success healing severe chemical burns and scarring
         | to the cornea. Here's video of them talking about their effort
         | to get it FDA approved (will take 5 years), I linked it to
         | where it shows the before and after results:
         | https://youtu.be/q_obgXSeLaU?t=1586
        
         | kak9 wrote:
         | This is really fantastic reply and context. Thanks for posting
         | this!
         | 
         | When you see research like this, assuming all things trend
         | positive (big if of course) what is the timeframe one expects
         | to see it make its way to mainstream application?
        
         | mkl wrote:
         | I would like to second the eye rubbing awareness. I have
         | keratoconus in both eyes, and had two (donor) corneal
         | transplants in the 1990s, in my teens. Even with them, my sight
         | is not great, as the distortions from the transplant scarring
         | and residual keratoconus around the edges are only partially
         | correctable with regular glasses lenses (I think these
         | artificial corneas would not be better). I had bad hayfever as
         | a kid (and still do sometimes now) and rubbed my eyes a lot. I
         | now think it's the most likely cause.
         | 
         | Don't let your kids rub their eyes!
        
           | EvanAnderson wrote:
           | I am in a similar boat-- fairly bad animal allergies and hay
           | fever as a child accompanied with frequent and vigorous eye
           | rubbing and now keratoconus (though, fortunately, not so far-
           | progressed as to need corneal transplants).
           | 
           | My daughter has the same characteristic long eyelashes that I
           | do, and exhibits allergies (though much less severe than
           | mine). My wife and I have made a very strong effort to
           | prevent her from eye-rubbing. She's old enough now to
           | understand why we were so adamant about it.
           | 
           | I'm seeing elsewhere in this thread that nocturnal eye
           | rubbing can be a problem. I never thought about that and it's
           | a bit disturbing. I do remember waking-up with my eyes
           | plastered shut with hardened mucus as a child.
        
         | Aerroon wrote:
         | Interesting! How much eye rubbing are we talking about? Several
         | times a day? Once a day? Once a week? Any tips on stopping the
         | habit?
        
           | gdebel wrote:
           | To start with, full disclosure : this is a controversial
           | topic. The majority of eye surgeons are still convinced that
           | there is a genetic predisposition to keratoconus, and that
           | eye rubbing is an optional trigger. Other (a growing number)
           | think that this is the sole responsible of keratoconus.
           | 
           | My mentor is the main proponent of the eye rubbing theory. I
           | was a skeptic, and became convinced by learning with him how
           | to properly interview patients on this subject, how to
           | prevent eye rubbing, and by seeing the absence of progression
           | after full awareness of the patients (without cross-linking.
           | We don't do any CXL in my department, ever. KC screening and
           | care is one of our main activity: not doing CXL is a
           | financial loss). My mentor's website :
           | https://www.gatinel.com/recherche-
           | formation/keratocone-2/no-... (No conflict of interest except
           | loyalty).
           | 
           | The main difficulty is that it is almost impossible to design
           | an experiment to prove the theory (if someone has a genius
           | idea, please don't hesitate). Usually other surgeons or
           | students become convinced after visiting the department and
           | spread the good practices back home : still a long way to go.
           | 
           | The harmful eye rubbing is made with the hard parts of the
           | hand (knuckles). It is frequently nocturnal and almost
           | everytime ignored. Awareness comes when the patient has been
           | informed and told to look for this habit. At the second
           | consultation, the eye rubbing is reported in the vast
           | majority of cases. I count the keratoconus patients that deny
           | eye rubbing after 2-3 consultations on one hand. We prescribe
           | a transparent eye shell to sleep with when the patient denies
           | eye rubbing : it allows them to realize that they rub during
           | the night. We prescribe eye drops to ease the eye irritation
           | which triggers rubbing, and instruct to rub the inner part of
           | the eyelid, against the nose (no eye deformation) if
           | necessary. Sleep position is frequently pathological too (eye
           | vs hand or arm contact. In those cases the KC is very
           | asymetrical).
           | 
           | Doctors in our team can predict the eye rubbing habit
           | frequency and intensity by looking at a corneal topography.
           | It is incredible that the role of this habit was ignored so
           | long. I suppose that we doctors don't talk enough with our
           | patients. The financial incentive of performing CXL and
           | surgeries is so clearly detrimental the the adoption of those
           | practices.
        
             | keratothrowaway wrote:
             | Hi, I am really interested in reading this conversation, as
             | I have keratoconus and had CXL surgery about ten years ago,
             | and am very happy with it. The CXL stopped the keratoconus
             | progressing and I only need to wear glasses instead of the
             | more invasive things other patients mention (contact
             | lenses, corneal grafts and transplants, etc).
             | 
             | It would be good if this intervention to convince patients
             | to cease eye rubbing was more common in keratoconus
             | patients. There is often a delay of several months between
             | when keratoconus is suspected or diagnosed and CXL is
             | carried out (in my case I had to wait 6 months in one eye
             | and 9 months in the other, during which time it got a bit
             | worse).
             | 
             | About eye rubbing, yes there should be more awareness of
             | it! In practical terms, I would recommend that everyone
             | tries wearing an eye-mask when they're asleep (I recently
             | bought this one, and I'm happy with it
             | https://www.amazon.co.uk/gp/product/B07DW32QYJ ). This is
             | because it's more difficult to notice and prevent yourself
             | from rubbing your eyes when you're half-asleep.
             | 
             | There are several reasons why I like wearing an eye mask
             | while in bed, and some even apply to people who don't have
             | keratoconus: 1. It stops me rubbing my eyes when I'm in
             | bed. 1. It might stop allergens getting into my eyes when
             | I'm asleep, for example I notice much less rheum on my eyes
             | when I wake up in the morning. When I'm in bed is when I
             | notice that my allergies are worst. 3. It helps me sleep
             | better, it's like having blackout curtains in my room. 4.
             | If I want to get up in the middle of the night, I will be
             | able to see better in the dark.
        
       | Mauricebranagh wrote:
       | Realy interesting I have badly scared cornea from Sarcoidosis in
       | one eye - I wonder if this would work for me
        
       | airstrike wrote:
       | Amazing. In 25 years, this may be a packaged as a mod.
       | 
       | Paging The Expanse fans...
        
         | BLanen wrote:
         | No
        
         | flixic wrote:
         | Or they can rebrand as Kiroshi Optics.
        
       | schmorptron wrote:
       | That is INSANE! I really hope this is true and becomes viable for
       | as many people as possible as fast as possible. The team that
       | created this can really be proud.
        
       | nazbuck wrote:
       | https://www.israelhayom.com/2021/01/12/blind-man-sees-again-...
       | 
       | Imsraeli startup gives blind man sight with "artificial" corneas.
       | In other news a sharp increase in Palestinian children losing
       | their eyes
        
         | muggermuch wrote:
         | I'm guessing all technological advances performed by US tech
         | companies are post-fixed with information about starving Yemeni
         | children whose parents were bombed out of existence. /s
         | 
         | Sometimes one can appreciate tech advances without apportioning
         | blame for other societal ills at the doorsteps of folks who are
         | focused on making lives better for all.
         | 
         | PS: I'm not Israeli/Palestinian. I don't have a dog in this
         | fight, just came here to appreciate the news.
        
           | gkfasdfasdf wrote:
           | The US has not been occupying Yemen for the last 50+ years or
           | completely encircling their borders to create an open air
           | prison. Please, educate yourself on the conflict!
        
           | DSingularity wrote:
           | Do you know what doesn't increase the pressure on a brutal
           | occupation whose operations wreck the livelihoods of
           | thousands of Palestinians daily? That's right, not bringing
           | up the Israeli occupation whenever possible.
           | 
           | We bring hope to the Palestinians when we don't ignore their
           | suffering.
        
         | gkfasdfasdf wrote:
         | Like how Israel is leading the world in vaccinations per
         | capita! As long as the you exclude the Palestinian population
         | that is...
        
           | DSingularity wrote:
           | And now we arrive to the beauty of the two state solution for
           | Israel. The Palestinians stay subjugated in practice but in
           | the eyes of the law they are an independent state.
           | 
           | But what else do you expect from an occupation which counts
           | the calories of the Gazans to make sure they only import what
           | is needed to survive?
        
           | gadders wrote:
           | The Palestinians refused assistance from Israel. Instead they
           | asked WHO to help. They have only recently requested vaccines
           | from Israel: https://www.jpost.com/arab-israeli-
           | conflict/palestinians-acc...
        
       | newbie578 wrote:
       | Wow, simply amazing, love to read articles like this. Also, I
       | keep being amazed at the amount of innovation and startups that
       | keep coming from Israel. There should be dozens of case studies
       | made and books written about what they are doing.
       | 
       | If someone already knows some books about it, please do
       | recommend.
        
       | widespace wrote:
       | You're bombarded with so much negative news on a daily basis that
       | it's nice to read something this inspiring!
        
       | edumucelli wrote:
       | One thing that surprised me is how the whole product comes in a
       | "kit" with instructions and tools. I never thought on those
       | medical devices as something that would come as a lego brick,
       | mainly something that has a huge potential as this. I thought
       | that to perform this kind of operation a ton of material was
       | necessary.
        
         | roveo wrote:
         | Tooth implants also come as "kits".
        
         | BLanen wrote:
         | That's actually not that uncommon.
        
         | magicpin wrote:
         | Often times when a surgeon is using a product for the first
         | time, a representative from the medical device manufacture will
         | watch the surgery and provide guidance with a laser pointer.
        
         | wittyreference wrote:
         | Most medical stuff comes as kits. In no small part because each
         | individual manufacturer tends to have their own process for the
         | details - it's not as interchangeable as you'd think. In part I
         | think it's a liability thing.
         | 
         | It also helps _a lot_ with sterility.
        
         | bluetwo wrote:
         | All the fancy bone reconstruction plates come in kits like this
         | with step-by-step instruction manuals.
        
       | interestica wrote:
       | Okay this is very cool. Artificial or 3D-Printed corneas seem
       | like such an obvious target for development.
       | 
       | > "Unveiling this first implanted eye and being in that room, in
       | that moment, was surreal."
       | 
       | Still nowhere close to an 'implanted eye'...And I don't like that
       | that sentence is being picked up.
       | 
       | The 'install' kit is very interesting. Install Animation:
       | https://www.corneat.com/kpro-animation
       | 
       | Pitch/Deck: https://resiconference.com/digital-resi-
       | january-2021-agenda/...
        
       | [deleted]
        
       | _0ffh wrote:
       | Given that cornea transplants are routine operations, why was
       | that man left blind for so long? Where there any medical factors
       | precluding the use of a donor organ?
       | 
       | Don't get me wrong, this is fantastic news, but something
       | essential has been left out of this article.
        
         | tyingq wrote:
         | From a different article:
         | 
         |  _" He had four donor transplants to try to restore his vision,
         | but all failed."_
         | 
         | https://www.israel21c.org/jamal-can-see-again-thanks-to-new-...
        
           | _0ffh wrote:
           | Thanks, that sure clears things up!
        
             | tyingq wrote:
             | I see what you did there :)
        
         | wccrawford wrote:
         | Maybe he couldn't afford the operation and the company gave it
         | to him because they needed to try it out?
         | 
         | I don't think that there has to be anything exceptional going
         | on here just because he was blind for 10 years at 78 years old.
        
           | _0ffh wrote:
           | Well that's true, or maybe he was down-prioritized for donor
           | organs due to his age. I've got a friend who isn't allowed to
           | drive a car because of bad corneas. He also got repeatedly
           | rejected when trying to apply for a donor organ, because he
           | is still far from blind, so his inability to drive is
           | classified as a comparatively mild inconvenience. I'd just
           | have thought that someone who actually _is_ effectively blind
           | would be able to get one. I 'm sure my friend will be
           | thrilled to hear about this development, he's been waiting
           | for something like this for years, nay decades! When
           | production ramps up he might finally be able to get his full
           | eyesight back!
        
       | UI_at_80x24 wrote:
       | I am a recipient of a dual cornea transplant because of a
       | condition called: Fuch's Cornea Dystrophy.
       | 
       | In 5-20 years I'll need it again.
       | 
       | I'm not in as bad of shape as the person in TFA. I'm damn lucky,
       | but to be honest, I'm miserable. I remember what it was like to
       | have lazer-sharp vision. Now I can't work with electronics
       | anymore. My soldering iron is gathering dust. I can't do 30% of
       | my job. Hell I have to assemble PC's by feel. I can't see the
       | writing on jumper connections, and spend a lot of time taking a
       | picture of a thing and then magnifying the image just trying to
       | figure out what goes where.
       | 
       | It's a shame I am not a mechanic, bolts are much bigger then
       | jumpers. Working by feel is a fucking bitch.
        
         | wiiittttt wrote:
         | I'm sorry to hear that. My sister has Fuch's Dystrophy as well
         | and also had a double cornea transplant, but it seems to have
         | mostly fixed all of her vision issues. Time will tell if I'm in
         | the same boat, but so far have no signs of it.
        
         | gdebel wrote:
         | I sympathize. I don't know what kind of procedure you
         | underwent. If the blurry vision comes form an irregular
         | anterior corneal surface, scleral lenses can be a game-changer.
         | Also, cellular therapy could be an option in a few years,
         | you're not condemned to another surgery with a little bit of
         | luck. Don't hesitate to write me if you need an informal,
         | general advice.
        
           | spitfire wrote:
           | What is your contact information?
        
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