[HN Gopher] A noninflammatory mRNA vaccine for treatment of auto...
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A noninflammatory mRNA vaccine for treatment of autoimmune
encephalomyelitis
Author : lawrenceyan
Score : 41 points
Date : 2021-01-07 20:55 UTC (2 hours ago)
(HTM) web link (science.sciencemag.org)
(TXT) w3m dump (science.sciencemag.org)
| DubiousPusher wrote:
| Were it to work in humans, does anyone know if there is any
| reason such an approach couldn't be extended to other autoimmune
| disorders which attack the various other tissues of the body?
| _Microft wrote:
| I think this is what they are eventually aiming for. Half of
| the authors is affiliated with BioNTech of BioNTech/Pfizer-
| mRNA-vaccine-fame by the way.
| weaksauce wrote:
| that's why i've been saying that the mRNA vaccine delivery
| method could be the next paradigm shift... like antibiotics
| were.
| RobertoG wrote:
| I think that this could be thought as part of a more
| general revolution: the know-how to program the immune
| system. This would include things like T-Cells therapy for
| cancer (1)
|
| (1) - https://science.sciencemag.org/content/371/6525/145
| jjcon wrote:
| When people think vaccine they think, 'only effective if
| taken beforehand'. Is that the case for mRNA vaccines?
| iandanforth wrote:
| Please check my understanding:
|
| Some cells in the body present features that teach the immune
| system that these features are 'OK' and part of the healthy body
| and shouldn't be attacked.
|
| This therapy seeks to cause those cells to produce features, or
| produce more of some features, that are being incorrectly
| recognized as 'bad' by the immune system. Thus correcting the
| immune systems 'understanding' and suppressing mistaken attacks
| on the body which underlies auto-immune disorders.
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(page generated 2021-01-07 23:01 UTC)