https://geneguessr.brinedew.bio/ Tags Search [ ] Content * apps GeneGuessr - Daily Protein Guessing Game How to Play GeneGuessr Welcome to GeneGuessr! This is the protein of the day. Can you figure out which gene made it? You will see spoiler bars that cover valuable hints. Tap the spoiler bar to reveal a hint underneath. Look up your favorite gene with the search bar. Submit it as your first guess. Feedback cards Each of your guesses will appear as a feedback card. The feedback bar percentage shows how close you got. Look for highlighted properties. They match your target. Revealing hints It costs 1 hint to remove a spoiler bar. You get +1 hint for each guess. When the hint is too obvious, the bar stays locked. Just try unlocking another one. You get to make 10 guesses before the game ends. Feel free to experiment! --------------------------------------------------------------------- > Sources Protein data: UniProt Gene nomenclature: HGNC Gene summaries: NCBI Gene Gene Ontology: GO Consortium Domains & clans: InterPro / Pfam Architecture: CATH Pathway data: Reactome Tissue specificity: Human Protein Atlas RNA expression (tau metric) 3D structures: RCSB PDB, AlphaFold DB, SWISS-MODEL Structure viewer: Mol* (via PDBe integration) Similarity: HiG2Vec, ESM2 Origin age: Litman T & Stein WD (2019). Obtaining estimates for the ages of all the protein-coding genes and most of the ontology-identified noncoding genes of the human genome, assigned to 19 phylostrata Semin Oncol 46(1):3-9 First publication year: Zwick ME, Kraemer SA & Carter GW (2019). Dataset of frequency patterns of publications for human protein-coding genes. Data Brief 28:104770 Privacy Policy --------------------------------------------------------------------- Created with Quartz v4.5.1 (c) 2025 * About * Support me