https://bgr.com/science/frozen-human-brain-tissue-was-successfully-revived-for-the-first-time/ Click to Skip Ad Closing in... [p] * Subscribe [ ] Search * News + Tech + Entertainment + Science + Business + Lifestyle * Reviews * Best * Guides * Deals * More + Accessories + Apps & Software + Audio + Cameras + Cars + Computers + Gaming + Home & Kitchen + Home Theater + How To + Jobs + Mobile + Security + Shows + Smart Home + Space + Tablets + About Us Sign up for our daily newsletter Subscribe * About BGR * Advertising * Contact Us TRENDING: New on Netflix iPhone 16 Pixel 8a iOS 17.5 Netflix Originals iOS 18 Free Streaming Apps macOS 15 Best Deals Home Science News Frozen human brain tissue was successfully revived for the first time [joshua] By Joshua Hawkins Published May 17th, 2024 8:12PM EDT dramatic frozen human brain concept Image: fergregory / Adobe If you buy through a BGR link, we may earn an affiliate commission, helping support our expert product labs. Scientists finally found a way to thaw frozen human brain tissue without damaging it. In a groundbreaking development, scientists have discovered a new technique that allows human brain tissue to be frozen and thawed while maintaining its normal function. This breakthrough, achieved by a team led by Zhicheng Shao at Fudan University in Shanghai, China, could potentially revolutionize the study of neurological conditions. The researchers detailed their findings in Cell Reports Methods. The team says it grew self-organizing brain samples, known as organoids, from human embryonic stem cells for three weeks, allowing the development of neurons and neural stem cells. They then tested various chemical compounds to determine which combinations could help keep the frozen human brain tissue alive and enable growth after thawing. The most successful combination consisted of methylcellulose, ethylene glycol, DMSO, and Y27632. The researchers call it MEDY, and they suspect it somehow interferes with a pathway that would otherwise initiate cell death, allowing for the tissue to freeze and be thawed without incident. Tech. Entertainment. Science. Your inbox. Sign up for the most interesting tech & entertainment news out there. [ ] Email: [ ] SIGN UP By signing up, I agree to the Terms of Use and have reviewed the Privacy Notice. brain MRIThe X-ray of the human brain closeup image Image source: merydolla / Adobe To test the effectiveness of MEDY, the team conducted a series of experiments on brain organoids of different ages, ranging from 28 to over 100 days old. They found that the thawed organoids closely resembled their unfrozen counterparts' appearance, growth, and function, even after being frozen in MEDY for 18 months. Similar results were observed across frozen human brain tissue representing different brain regions. The researchers also applied their technique to three-millimeter cubes of brain tissue from a 9-month-old girl with epilepsy. The tissue maintained its pre-freezing structure and remained active in a laboratory culture for at least two weeks after being thawed. According to researchers from the University of Surrey and the University of Birmingham in the UK, this breakthrough in freezing human brain tissue could lead to improved investigations of brain development in the lab for health research. While significantly more research and the use of larger tissues are needed, some suggest that this work could eventually lead to the freezing of entire brains. Some scientists envision a future where patients with terminal conditions or astronauts traveling to distant star systems could be cryopreserved, with MEDY representing "one small step" towards that goal. Don't Miss: Japan OKs hunting endangered fin whales as whale meat vending machines grow more popular This article talks about: Brain research [joshua] Joshua Hawkins Writer Josh Hawkins has been writing for over a decade, covering science, gaming, and tech culture. He also is a top-rated product reviewer with experience in extensively researched product comparisons, headphones, and gaming devices. Whenever he isn't busy writing about tech or gadgets, he can usually be found enjoying a new world in a video game, or tinkering with something on his computer. 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