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Elsevier

Research Policy

Volume 51, Issue 1, January 2022, 104329
Research Policy

Patent Toxicity

Author links open overlay panelGianlucaBiggi^aElisaGiuliani^bArianna
Martinelli^cEmilioBenfenati^d
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https://doi.org/10.1016/j.respol.2021.104329Get rights and content

Research Highlights

*

    Chemical toxicity is an issue of policy concern and a toxic-free
    future is one of the goals of the EU Green Deal.

*

    We combine patent analysis with computational toxicology and
    develop a methodological roadmap to measure patent toxicity.

*

    Patent toxicity measures the extent to which a patent includes
    chemical compounds that are toxic to humans and/or the
    environment

Abstract

A toxic-free world is one of the goals of the European Green Deal and
a key objective of the World Health Organization Inter-Organization
Programme for the Sound Management of Chemicals. However, although
use of some toxic chemicals is being banned, others continue to be
developed. We consider this motivation for a closer examination of
the toxicity of chemical inventions. We combine patent analysis with
computational toxicology and develop a methodological roadmap to
measure patent toxicity, that is, the extent to which a patent
includes "components" (or compounds) that are toxic to humans and/or
the environment. To illustrate our proposed methodology, we analyse
the toxicity of ten well-known hazardous chemicals and compare it
against that of other groups of chemical patents. We suggest that the
measurement of patent toxicity opens up interesting avenues for
future research with, potentially, strong policy implications.

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Keywords

Patents
Patent toxicity
Computational toxicology
QSAR models
Chemical inventions
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