Posts by CastlTrAstonDrs@med-mastodon.com
(DIR) Post #AdNLqHnN3CcCDBwjjc by CastlTrAstonDrs@med-mastodon.com
2023-12-30T12:33:50Z
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#IDMastodon 🧵by @mvankerkhove @WHO From limited number of countries reporting, there has been a 35% ⬆️ in #COVID19 🏥& ICU admission in the last month. #SARSCoV2, influenza & other respiratory pathogens continue to be on the rise with the current surge in respiratory diseases & JN.1 subvariant. Take measures to protect yourself from infection #MaskUp 😷 and Get boosted https://x.com/mvankerkhove/status/1741004970936480181?s=61
(DIR) Post #AdNLvBg7DlRWgitEdE by CastlTrAstonDrs@med-mastodon.com
2023-12-30T20:47:48Z
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#IDMastodon #covidheart After several countries witnessed a surge in #COVID cases in recent weeks, largely due to the influx of a new strain JN.1, health experts have warned that this will increase the chances of potential heart issues for those who catch the disease. It could trigger a "#heartfailure pandemic" https://mainichi.jp/english/articles/20231226/p2a/00m/0sc/047000c
(DIR) Post #AdNLvEYQWo4jbkJdZ2 by CastlTrAstonDrs@med-mastodon.com
2023-12-30T20:52:14Z
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Predicted risk of #heartfailure pandemic due to persistent #SARSCoV2 infection https://www.cell.com/iscience/fulltext/S2589-0042(23)02718-9
(DIR) Post #AdNowdfFYJJcRgWsWe by CastlTrAstonDrs@med-mastodon.com
2023-12-31T13:01:51Z
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#iDMastodon #CovidIsNotOver So it’s just beginning #Maskup😷#Getboosted According to @cdcgov JN.1 accounted for 44 % of #SARSCoV2 infections nationwide by mid-Dec , up from about 7 % in late Nov . @thehill https://thehill.com/policy/healthcare/4380733-hospitals-reinstating-mask-requirements-rise-covid/
(DIR) Post #AhERow0kAkyG6AIlay by CastlTrAstonDrs@med-mastodon.com
2024-04-24T17:47:05Z
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#IDMastodon #Viralpathogenesis #neurocovid .A role for #SarsCoV2 & synaptic transmission. #SARSCoV2 infection can be associated with ‘brain fog’ & persistent neurologic disease, especially in the elderly, with the possibility of direct viral particle interference with normal synaptic transmissionhttps://www.nature.com/articles/s41564-024-01657-2.pdf
(DIR) Post #AhERoxaEKIx0yVucXw by CastlTrAstonDrs@med-mastodon.com
2024-04-24T19:59:20Z
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#neuroimmunology #Neuroinflammation #Clinicalreviews & Recap Roles of #meningealimmunity on homeostatic 🧠 functions & infection 📌 https://link.springer.com/article/10.1186/s12950-023-00374-7 📌 https://www.sciencedirect.com/science/article/pii/S0306452224000575 📌 https://www.cell.com/trends/immunology/abstract/S1471-4906(24)00065-6?rss=yes&utm_medium=twitter&utm_source=dlvr.it Resident tissue #macrophages: Key coordinators of tissue homeostasis beyond #immunity. https://www.science.org/doi/pdf/10.1126/sciimmunol.add1967?download=true
(DIR) Post #AhERozJHuGaSKY07Ps by CastlTrAstonDrs@med-mastodon.com
2024-04-24T19:59:20Z
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Understanding of the intricate relationship between #microglia & CNS-infiltrating macrophages in vivo for viral-induced MS & epilepsy pathogenesis 📌 https://www.mdpi.com/1999-4915/16/1/119 📌 https://www.mdpi.com/2227-9059/12/3/632
(DIR) Post #AhERp0h4lJD2cc8d8K by CastlTrAstonDrs@med-mastodon.com
2024-04-24T19:59:20Z
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In utero infection and maternal inflammation can adversely impact fetal brain development…cytokines in pregnancies affected by maternal #SARSCoV2 infection in early and late … https://www.biorxiv.org/content/10.1101/2024.02.21.581282v1.full.pdf
(DIR) Post #AhjVu10kyh8qBPzIIK by CastlTrAstonDrs@med-mastodon.com
2024-05-09T22:37:48Z
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#IDMastodon Much of what we learned in school about how we taste is wrong. Progress in understanding how taste works is providing insights that may help in the management of #obesity, #diabetes, #COVID19 & other illnesses. https://www.nejm.org/doi/pdf/10.1056/NEJMra2304578
(DIR) Post #Ahq9zBozNKvOH0GUZk by CastlTrAstonDrs@med-mastodon.com
2024-05-06T09:11:46Z
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#IDMastodon Durable #Tcell responses to #SARSCoV2 antigens after infection or vaccination improve immune-mediated #viralclearance. To date, population-based surveys of #COVID19 #adaptiveimmunity have focused on testing for IgG antibodies that bind spike protein and/or neutralize the virus. Deployment of existing methods for measuring #Tcellimmunity could provide a more complete profile of immune status, informing #publichealth policies and interventions. https://www.science.org/doi/10.1126/sciimmunol.abo1303?utm_medium=ownedSocial&utm_source=Twitter&utm_campaign=SciImmunology
(DIR) Post #AhrWqjLVr3BXkHNBlQ by CastlTrAstonDrs@med-mastodon.com
2024-05-06T09:23:02Z
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A spark can set a whole forest on fire. Just a spark. Save it…Charles BukowskiA walk in The Old Town -Oxford
(DIR) Post #AhrxGXHFwhRqeWLbyC by CastlTrAstonDrs@med-mastodon.com
2024-05-12T13:00:42Z
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#IDMastodon #publichealth #PublicHealth #Epidemiology The Oxford-AstraZeneca vaccine was a critical part of the #COVID19pandemic response. #AstraZenecavaccine: hounded by fake news to the last …@conversationuk https://theconversation.com/astrazenecas-covid-vaccine-withdrawn-right-to-the-end-it-was-the-victim-of-misinformation-229653?utm_medium=email&utm_campaign=The%20Weekend%20Conversation%20-%202966130163&utm_content=The%20Weekend%20Conversation%20-%202966130163+CID_68e154275f22a9a5f8e569b0812c854d&utm_source=campaign_monitor_uk&utm_term=AstraZenecas%20COVID%20vaccine%20withdrawn%20%20right%20to%20the%20end%20it%20was%20the%20victim%20of%20misinformation
(DIR) Post #AhrxZYvm1ROpHbN7JI by CastlTrAstonDrs@med-mastodon.com
2024-05-13T19:06:41Z
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#IDMastodon #Publichealth #epidemiology #cardiomastodon #Heartfailure patients who are vaccinated against #COVID19 have an 82% greater likelihood of living longer than those unvaccinated Patients…https://www.eurekalert.org/news-releases/1043942
(DIR) Post #Ahrxg9cmVcECp8dDzU by CastlTrAstonDrs@med-mastodon.com
2024-05-13T22:48:29Z
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#IDMastodon #Neuroinflammation #NeuroCovid Among #LongCOVID patients, cognitive symptoms are the most frequently reported complaints (22–51.1% ) & so far have been described to mainly affect concentration/attention, memory , receptive language and/or executive function ,
(DIR) Post #AhrxgBCycWm7jgZe2y by CastlTrAstonDrs@med-mastodon.com
2024-05-13T22:48:29Z
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patients seem to be at higher risk of developing psychiatricdisorders(anxiety disorder,mood disorder/depression, insomnia) after 6 months from #SARSCoV2 infection vs influenza or other respiratory pathogens or control cohorts surviving sepsis caused by different pathogens . The underlying pathomechanisms remain subject of ongoing scientific research and discussion and include direct viral infection of CNS, severe systemic or neuroinflammation, microvascular thrombosis, neurodegeneration,
(DIR) Post #AhrxgD0dvM67K0op6G by CastlTrAstonDrs@med-mastodon.com
2024-05-13T22:48:29Z
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but also deconditioning, PTSD & others .Studies investigating possible neuroradiological correlates for neuropsychological alterations in LC describe subtle white matter abnormalities of 🧠, decreased grey matter volume , reduction of global 🧠 size, tissue damage in 🧠 regions functionally connected to the primary olfactory cortexCharacterization of cognitive symptoms in #postCOVID19 patientshttps://link.springer.com/article/10.1007/s00406-024-01821-z
(DIR) Post #AjYJPSisoEFV98cRH6 by CastlTrAstonDrs@med-mastodon.com
2024-07-03T11:41:22Z
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#IDMastodon #neurocovid @jamanetworkopen In this cohort study of 311 hospitalized older adults with #COVID19, in-hospital #delirium was associated with increased functional disability and cognitive impairment over the 6 months following discharge. Older survivors #COVID19 hospitalization who experience in-🏥 delirium should be assessed for disability &cognitive impairment during postdischarge follow-up. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2820671
(DIR) Post #AjqbzOjEQuvfCfLVM8 by CastlTrAstonDrs@med-mastodon.com
2024-07-12T06:31:36Z
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LongCovid is the endgame .Recovering from LongCovid - a great challenges and in the between are you downfall Infected with salmonella and take nearly 4 weeks to recover …😷 Be careful out thereFLiRT is merciless ….
(DIR) Post #AjrC9NYnEEjGpEWQ2S by CastlTrAstonDrs@med-mastodon.com
2024-07-12T14:09:27Z
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"The problem with being in the rat race is that even if you win, you’re still a rat."--Jed McKenna
(DIR) Post #Al7Dic5tREB4wxUU2C by CastlTrAstonDrs@med-mastodon.com
2024-08-19T05:46:33Z
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#IDMastodon #publichealth in perils This summer has seen a large #COVID 🌊 – one which is showing potential to be bigger than 2023 winter wave was.The current wave #FLiRT variants, which have acquired greater immune evasion and ability to enter our cells. The rise in #COVID19 cases across 🇬🇧 has also been accompanied by a spike in hospitalisations. COVID is not seasonal, as this current wave is stark evidence of… @TheConversationUK https://theconversation.com/covid-why-the-uks-autumn-vaccine-strategy-could-fail-patients-236825?utm_medium=email&utm_campaign=Latest%20from%20The%20Conversation%20for%20August%2016%202024%20-%203068031292&utm_content=Latest%20from%20The%20Conversation%20for%20August%2016%202024%20-%203068031292+CID_44c95120bd38877d054fb23bc2e97441&utm_source=campaign_monitor_uk&utm_term=COVID%20why%20the%20UKs%20autumn%20vaccine%20strategy%20could%20fail%20patients