Subj : Mediterranean diet associated with a low
To   : All
From : ScienceDaily
Date : Thu Jan 20 2022 21:30:48

 Mediterranean diet associated with a lower risk of mortality in older
adults 

  Date:
      January 20, 2022
  Source:
      University of Barcelona
  Summary:
      A greater adherence to the Mediterranean diet which had been
      assessed through an index made with biomarkers during a 20-year
      scientific monitoring is associated with a lower mortality in
      adults over 65.



FULL STORY
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A greater adherence to the Mediterranean diet which had been assessed
through an index made with biomarkers during a 20-year scientific
monitoring is associated with a lower mortality in adults over
65. This is one of the main conclusions of a study led by Cristina
Andre's-Lacueva, head of the Research Group on Biomarkers and Nutritional
& Food Metabolomics of the Faculty of Pharmacy and Food Sciences of the
University of Barcelona (UB) and the CIBER on Fragility and Healthy Ageing
(CIBERFES), also formed by the Food Innovation Network of Catalonia (XIA).


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he paper, published in the journal BCM Medicine, has been carried out
in collaboration with the National Institute on Ageing (NIA) of the
United States.

According to the conclusions, the analysis of dietary biomarkers in
plasma and urine can contribute to the individualized food assessment
for old people. The study is based on the InCHIANTI project, conducted
in the region of the Italian Tuscany, a study that has been carried
out during twenty years in a total of 642 participants (56% women) aged
over 65 or more and which enabled researchers to obtain complete data
on food biomarkers.

As stated by the UB Professor Cristina Andre's-Lacueva, head of the
research group in CIBERFES, "we develop an index of dietary biomarkers
based on food groups that are part of the Mediterranean diet, and we
assess their association with mortality."  In the study, researchers chose
the reference levels of the following dietary biomarkers in the urine:
total polyphenols and resveratrol metabolites (from grape intake) and
presents in plasma, plasma carotenoids, selenium, vitamin B12, fatty acids
and their proportion of monounsaturated and saturated fatty acids. Using
a predictive model, they assessed the associations of the Mediterranean
diet index and the food-frequency questionnaire (FFQ) with mortality.

During the twenty years of monitoring, there were 425 deaths (139 due
to cardiovascular diseases and 89 due to cancer-related causes). Once
the models were analysed, the score of the Mediterranean diet using the
biomarkers was inversely associated with all causes of death.

This study highlights the use of dietary biomarkers to improve the
nutritional assessment and guide a customized assessment for older
people. As noted by the CIBERFES researcher of the UB Toma's Meron~o,
co-first signatory of the study, the researchers "confirm that an
adherence to the Mediterranean diet assessed by a panel of dietary
biomarkers is inversely associated with the long-term mortality
in older adults, which supports the use of these biomarkers in
monitoring evaluations to study the health benefits associated
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Story Source: Materials provided by University_of_Barcelona. Note:
Content may be edited for style and length.


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Journal Reference:
   1. Nicole Hidalgo-Liberona, Toma's Meron~o, Raul Zamora-Ros, Montserrat
      Rabassa, Richard Semba, Toshiko Tanaka, Stefania Bandinelli, Luigi
      Ferrucci, Cristina Andres-Lacueva, Antonio Cherubini. Adherence to
      the Mediterranean diet assessed by a novel dietary biomarker score
      and mortality in older adults: the InCHIANTI cohort study. BMC
      Medicine, 2021; 19 (1) DOI: 10.1186/s12916-021-02154-7
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Link to news story:
https://www.sciencedaily.com/releases/2022/01/220120103400.htm

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