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To: bionet-announce@net.bio.net
From: Mhairi Marshall <mm1@sanger.ac.uk>
Subject: Pfam release 6.5
Organization: sanger centre
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               ANNOUNCING PFAM RELEASE 6.5
                ===========================


Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models.
Pfam families contain functional annotation and cross-references to
other databases.  Query sequences can be searched against the Pfam
library of profile hidden Markov models at the web sites below.

Pfam 6.5 contains 2929 families.  69% of proteins in SWISSPROT 39
and TrEMBL 14 have at least one match to a Pfam family.


For interactive access and searching see URLs

               http://www.sanger.ac.uk/Software/Pfam
               http://pfam.wustl.edu
               http://www.cgr.ki.se/Pfam

The release is also available in flat file by anonymous ftp:

               ftp://ftp.sanger.ac.uk/pub/databases/Pfam/
               ftp://ftp.genetics.wustl.edu/pub/Pfam/
               ftp://ftp.cgr.ki.se/pub/data/Pfam/

The Pfam HMM library is compatible with HMMER2 software, available
from
               http://hmmer.wustl.edu/

and also the Wise2 software, available from

               http://www.sanger.ac.uk/Software/Wise2/

___________________
The Pfam consortium
07-01


.