From owner-metabolic-reg@net.bio.net Fri Oct 15 11:56:00 1999 Path: biosci!VALIANT.NIEHS.NIH.GOV!kohn From: kohn@VALIANT.NIEHS.NIH.GOV ("Michael Kohn") Newsgroups: bionet.metabolic-reg Subject: Re: OTC Date: 15 Oct 1999 05:55:58 -0700 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 23 Sender: daemon@net.bio.net Distribution: world Message-ID: <9910150840.ZM8874@valiant.niehs.nih.gov> References: NNTP-Posting-Host: net.bio.net You are probably referring to ornithine transcarbamylase (EC 2.1.3.3), also called ornithine carbamoyltransferase. This is a mitochndrial enzyme found primarily in the liver. It catalyzes the conversion of ornithine to citrulline as part of the urea cycle, which is responsible for production of urea from the nitrogen in excess amino acids. -- Michael C. Kohn Laboratory of Computational Biology and Risk Analysis National Institute of Environmental Health Sciences P.O. Box 12233, Mail Drop A3-06 Research Triangle Park, NC 27709-2233 Telephone: 919-541-4929 (voice) 919-541-1479 (fax) e-mail: kohn@valiant.niehs.nih.gov Web site: http://valiant.niehs.nih.gov .