From owner-announce@net.bio.net Mon Aug 09 20:10:00 1999 Path: biosci!biosci!not-for-mail From: perriere@biomserv.univ-lyon1.fr (Guy Perriere) Newsgroups: bionet.announce Subject: ANNOUNCE: HOBACGEN release 5 availability Date: 9 Aug 1999 14:09:59 -0700 Organization: Universite Claude Bernard - Lyon 1 Lines: 51 Sender: daemon@net.bio.net Approved: kristoff@net.bio.net Distribution: world Message-ID: <7om181$ldp$1@tempo.univ-lyon1.fr> Reply-To: perriere@biomserv.univ-lyon1.fr NNTP-Posting-Host: net.bio.net Keywords: Database, homologous genes, bacteria HOBACGEN Release 5 (July 1999) The new release of HOBACGEN (the Homologous Bacterial Genes Database) is now available. Information on the database can be accessed at: http://pbil.univ-lyon1.fr/databases/hobacgen.html HOBACGEN is a database system that contains all the protein sequences of bacteria organized into families. It allows one to select sets of homologous genes from bacterial species and to visualize multiple alignments and phylogenetic trees. Thus HOBACGEN is particularly useful for comparative genomics, phylo- geny and molecular evolution studies on bacteria. The database contains all sequences of bacteria (eubacteria and archeae) and yeast taken from SWISS-PROT + TrEMBL, with some annotation modifications. It contains also all the corresponding nucleotide sequences from EMBL. Homologous proteins are clas- sified into families and multiple alignments and phylogenetic trees are computed for each family. This new version of HOBACGEN has been built using sequences from SWISS-PROT 37 (+ updates) and TrEMBL 10. Among the 102,369 proteins used to build this release, 82,464 are from eubacteria, 13,021 from archaea, and 6,883 from yeast. If you use HOBACGEN in a published work, please cite the following reference: Perriere, G., Duret, L. and Gouy, M. (1999) HOBACGEN: database system for comparative genomics in bacteria. submitted to Genome Research. Guy Perriere and Laurent Duret Laboratoire de Biometrie et Biologie Evolutive - UMR CNRS 5558 Universite Claude Bernard - Lyon 1 43, bd. du 11 Novembre 1918 69622 Villeurbanne Cedex France Email: {perriere, duret}@biomserv.univ-lyon1.fr .