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From: Kevin Howe <klh@sanger.ac.uk>
Newsgroups: bionet.announce
Subject: ANNOUNCING PFAM RELEASE 5.3
Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre
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                ANNOUNCING PFAM RELEASE 5.3
                ===========================


Pfam is a collection of protein domain family alignments which were
constructed semi-automatically using profile hidden Markov models.
Pfam families contain functional annotation and cross-references to
other databases.  Query sequences can be searched against the Pfam
library of profile hidden Markov models at the web sites below.

Pfam 5.3 contains 2216 families.  66% of proteins in SWISSPROT 38
and TrEMBL 11 have at least one match to a Pfam family.


For interactive access and searching see URLs

               http://www.sanger.ac.uk/Software/Pfam
               http://pfam.wustl.edu
               http://www.cgr.ki.se/Pfam

The release is also available in flat file by anonymous ftp:

               ftp://ftp.sanger.ac.uk/pub/databases/Pfam/
               ftp://ftp.genetics.wustl.edu/pub/Pfam/
               ftp://ftp.cgr.ki.se/pub/data/Pfam/

The Pfam HMM library is compatible with HMMER2 software, available
from
               http://hmmer.wustl.edu/

and also the Wise2 software, available from

               http://www.sanger.ac.uk/Software/Wise2/

___________________
The Pfam consortium
00-05





.