From owner-cellbiol@net.bio.net Sat Jan 11 22:00:00 1997 Path: biosci!rutgers!news.sgi.com!mr.net!newsfeeds.sol.net!hammer.uoregon.edu!news.icm.edu.pl!uw.edu.pl!news.nask.pl!01-newsfeed.univie.ac.at!swidir.switch.ch!news.grnet.gr!news.auth.gr!usenet From: "Stavros P. Zanos" Newsgroups: bionet.biophysics,bionet.cellbiol,bionet.immunology,bionet.molbio.proteins,bionet.molecules.peptides,bionet.neuroscience,sci.med.pharmacy Subject: Phosphorylation of G-proteins Date: 12 Jan 1997 10:15:11 GMT Organization: Medical School, Thessaloniki Lines: 15 Message-ID: <01bc000c$e56f1080$0f02000a@slirp.hol.gr> NNTP-Posting-Host: antigoni.med.auth.gr X-Newsreader: Microsoft Internet News 4.70.1155 Xref: biosci bionet.biophysics:2540 bionet.cellbiol:6398 bionet.immunology:10642 bionet.molbio.proteins:9709 bionet.molecules.peptides:598 bionet.neuroscience:17653 sci.med.pharmacy:39351 It has come to my knowledge that G proteins undergo phosphorylation by cAMP- and calcium-dependent protein kinases and by tyrosine kinases. Having undertaken the writing of a part of a seminar on autonomic NS pharmacology, I was wandering if anyone out there knew something about the physiological role of G protein phosphorylation, especially in relation to neurotransmission and synaptic plasticity processes. Any details on the phosphorylation sites and regulation are also welcome. References to book chapters or journal articles are welcome. Thank you in advance. S.P. Zanos Aristotle U. Med. School Thessaloniki, Greece .