From owner-celegans@net.bio.net Wed Mar 26 22:00:00 1997 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!europa.clark.net!cpk-news-hub1.bbnplanet.com!news.bbnplanet.com!newsxfer3.itd.umich.edu!agate!meyer.berkeley.edu!user From: jdlieb@mendel.berkeley.edu (Jason Lieb) Newsgroups: bionet.celegans Subject: In search of X-linked cosmids.... Date: Thu, 27 Mar 1997 14:14:02 -0800 Organization: Meyer Lab, UC Berkeley Lines: 13 Distribution: world Message-ID: NNTP-Posting-Host: meyer.berkeley.edu I'm interested in finding X-linked cosmids that, when injected, cause a Dpy phenotype. The ultimate goal is to find a minimal sequence that will support the binding of dosage compnesation factors to X. Any cosmid that is capable of binding such factors may cause a dosage compensation defect, leading to a DPY phenotype. If anyone has experienced an X-linked cosmid that causes a DPY or hermaphrodite-lethal phenotype when injected, I would greatly appreciate any information (or even strains!) that you might be willing to share. Thanks Jason Lieb jdlieb@mendel.berkeley.edu (510) 643-5583 .