From owner-metabolic-reg@net.bio.net Tue Mar 28 23:00:00 1995
Path: biosci!rutgers!gatech!swrinde!howland.reston.ans.net!pipex!warwick!news.ncl.ac.uk!usenet
From: Simon Eaton <S.J.Eaton@ncl.ac.uk>
Newsgroups: bionet.metabolic-reg
Subject: Re: help on coemzyme q10
Date: 29 Mar 1995 16:15:37 GMT
Organization: Newcastle University, UK
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Ubiquinone in plasma is usually measured by HPLC. You have to measure 
both oxidised and reduceed forms. Amount is approx. 1ug/ml plasma.
Refs:
 
Liver 14:138-140
Anal Biochem 157:106-116
Chem Pharm Bull 27:1237-1244
J Chrom 430:11-19
J Chrom 425:87-89.

Few studies of plasma ubiquinone have been made in pathological 
conditions although ubiquinone deficiency has been described (
Ogasahara S, Engel AG, Frens D, and Mack D. Muscle coenzyme Q deficiency 
in familial mitochondrial encephalomyopathy. Proceedings of the National 
Academy of Sciences of the United States of America  1989 Apr; 86: 
2379-82.)

Hope this is helpful
Simon Eaton

.