From owner-biophysics@net.bio.net Sun Mar 14 22:00:00 1999 Path: biosci!webtv.net!newsfeed.concentric.net!newspeer1.nac.net!news.maxwell.syr.edu!firehose.mindspring.net!170.140.150.7.MISMATCH!finch!hubcap.clemson.edu!sc.edu!usenet From: William Crymes Newsgroups: alt.bio.technology,alt.bio.technology.misc,bionet,bionet.biology,bionet.biophysics,bionet.cellbiol Subject: Re: gene development Date: Mon, 15 Mar 1999 10:32:48 -0500 Organization: Biologial Sciences, University of South Carolina Lines: 20 Message-ID: <36ED2820.A36ADE06@mail.biol.sc.edu> References: <7bf39i$o44@nnrp1.farm.idt.net> Reply-To: crymes@sc.edu NNTP-Posting-Host: 129.252.89.85 Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 4.5 [en] (Win95; I) X-Accept-Language: en Xref: biosci bionet.biophysics:4867 bionet.cellbiol:11477 Kirk- I think most developmentally altered genes are the effect of differential transcription. Such that type "A" gene is transcribed during embryogenesis and type "B" gene is transcribed later. Look up fetal hemoglobin vs. adult hemoglobin. The one set of genes that are extensively altered are the genes of the immune system. The gene the make-up the antibodies in the immune system are hyper-variable, though they vary not as a result of development but as a result of exposure to different antigens. Bill -- ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ William B. Crymes, Jr. University of South Carolina Department of Biological Sciences 700 Sumter Street Columbia, South Carolina 29201 Phone: (803)777-7105 Fax: (803)777-4002 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ .