From owner-btk-mca@hgmp.mrc.ac.uk Thu Dec 6 15:27:36 2001 Return-Path: Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 269C317AE0 for ; Thu, 6 Dec 2001 15:27:36 +0000 (GMT) Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 406BA17A82 for ; Thu, 6 Dec 2001 15:27:31 +0000 (GMT) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id C120417AE0 for ; Thu, 6 Dec 2001 15:27:28 +0000 (GMT) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id PAA04929 for btk-mca-list@hgmp.mrc.ac.uk; Thu, 6 Dec 2001 15:17:10 GMT X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: dbk@aber.ac.uk ("Douglas Kell") X-Newsgroups: bionet.metabolic-reg Subject: Re: Wholes and parts Date: 6 Dec 2001 15:17:09 -0000 Organization: BIOSCI/MRC Human Genome Mapping Project Resource Centre Lines: 32 Message-ID: <3C0F8C00.24491.61BF5EE0@localhost> References: Mime-Version: 1.0 Content-Type: text/plain; charset=ISO-8859-1 Content-Transfer-Encoding: Quoted-printable X-Complaints-To: news@net.bio.net X-Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 73F9617ADE for ; Thu, 6 Dec 2001 15:17:05 +0000 (GMT) X-Received: from braint.aber.ac.uk (braint.aber.ac.uk [144.124.16.42]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id BC09B17A82 for ; Thu, 6 Dec 2001 15:17:03 +0000 (GMT) X-Received: from pcbdad.dbs.aber.ac.uk ([144.124.113.30] helo=aardvark) by braint.aber.ac.uk with esmtp (Exim 3.21 #1) id 16C0Ga-0001Qv-00; Thu, 06 Dec 2001 15:16:52 +0000 X-To: athel@ibsm.cnrs-mrs.fr (Athel Cornish-Bowden) X-Reply-To: dbk@aber.ac.uk X-Cc: btk-mca@hgmp.mrc.ac.uk X-Priority: normal X-In-reply-to: X-Mailer: Pegasus Mail for Win32 (v3.12c) To: btk-mca@hgmp.mrc.ac.uk Sender: owner-btk-mca@hgmp.mrc.ac.uk Precedence: bulk >A remark > of Henrik Kacser's that Douglas Kell has quoted on occasion comes to min= d: > "But one thing is certain. If you want to understand the whole you need = to > study the whole". (Is that right Douglas? more or less what he said, > anyway). Pretty close! - the exact original is: =93But one thing is certain: to understand the whole you must look at the whole=94 Kacser, H. (1986). On parts and wholes in metabolism. In The organization of cell metabolism (ed. G. R. Welch and J. S. Clegg), pp. 327-337. Plenum Press, New York. All the best, Douglas. ******************************************************************** *(Prof.) Douglas B. Kell Phone: +44 1970 622334 * *Director of Research * = *Institute of Biological Sciences Fax: +44 1970 622354 * *Cledwyn Building * *University of Wales, Email: dbk@aber.ac.uk * *Aberystwyth SY23 3DD, U.K. http://qbab.aber.ac.uk/ * * http://www.abergc.com/* ******************************************************************** ******************************************************************** --- .