From owner-biophysics@net.bio.net Wed Apr 13 23:00:00 1994
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From: chembb@menudo.uh.edu (Enrico V. Cantu)
Newsgroups: bionet.biophysics
Subject: Re: Model membranes/Domains/Lipid-Protein..
Date: 14 Apr 1994 09:08:07 GMT
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knag@kean.ucs.mun.ca wrote:
: MODEL BIOLOGICAL MEMBRANES:: DOMAINS

: 3] What are the main functional relevance of biomembrane domains?

I don't know how what I have to say fits in, but I'm currently doing 
an undergraduate (to be followed up in grad. school after graduation)
thesis involving molecular dynamics of a simulated lipid bilayer.
I am still tinkering with the force field (all-atom CHARMm) but 
haven't produced a lot of data as of yet.  There is some crystal
data that I am eager to compare.  Most lipid bilayer models have been
constrained in ways that I and my advisor finds unacceptable, but
that's one of the reasons I'm working on this.

My goal is to eventually have the bilayer thermodynamically stable so 
that one of these years I can do some computational protein-lipid inter-
actions to study transmembrane domains of proteins and receptors.

I look forward to see this thread continue, even if what I'm doing is not
directly relevant to it yet.  Any e-mail would be appreciated as well.

	Cheers,
--
________________________________________________________________________
Enrico Cantu  Internet: ECantu@UH.edu  NeXTMail: enricoc@dna.bchs.uh.edu 

.