From owner-metabolic-reg@net.bio.net Fri Jan 26 22:00:00 1996 Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!news.sprintlink.net!news.telalink.net!news From: discus@mail.vci.net (kim and john) Newsgroups: bionet.metabolic-reg Subject: syndrome X and metabolic disregulation Date: 27 Jan 1996 22:21:15 GMT Organization: Your Organization Lines: 12 Message-ID: <4ee8gr$4ti@adam.telalink.net> NNTP-Posting-Host: port-1-1.vci.net Mime-Version: 1.0 Content-Type: Text/Plain; charset=US-ASCII X-Newsreader: WinVN 0.99.7 Syndrome X is a set of diseases manifesting in populations exposed to civilization. Depending on genetic vulnerability when exposed to civilization individuals in a native population can develop none, one, or any of the following cluster of diseases: obesity, type II diabetes, atherosclerosis, hypertension etc. The common denominator in syndrome X is an ad-lib diet with all the fat, salt, and calories people wish to consume. The studies on diet and aging seem to suggest some relationship between increased calories, decreased insulin sensitivity and increased free radical production with mitochondrial breakdown. Does anyone know of a good article, or database regarding these things? Thanks in advance John Ewing MD :) .