From owner-cellbiol@net.bio.net Tue Dec 24 22:00:00 1996 Path: biosci!TELEPORT.COM!probes From: probes@TELEPORT.COM (Dick Haugland) Newsgroups: bionet.cellbiol Subject: re: availability of lactacystin Date: 25 Dec 1996 08:56:17 -0800 Organization: Molecular Probes Inc. Lines: 10 Sender: daemon@net.bio.net Distribution: world Message-ID: <32C15C20.4941@teleport.com> Reply-To: dick@probes.mhs.compuserve.com NNTP-Posting-Host: net.bio.net Lactacystin apparently is not commercially available. However the active form of lactacystin (clasto-lactacystin beta-lactone) (active according to Dick et al in J Biol Chem 271, 7273 (1996)) presumably is available from the company Proscript (formerly Myogenics), 38 Sidney Street, Cambridge MA 02139; telephone 617-374-1470. They apparently have a development agreement on this and related inhibitors from Hoechst Marion Roussel. Dick Haugland Molecular Probes, Inc. .