From owner-bionews@hgmp.mrc.ac.uk Wed May 3 19:50:34 2000 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 8E2AE17B74; Wed, 3 May 2000 19:50:32 +0100 (BST) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 6022) id 3B15417ACE; Wed, 3 May 2000 19:50:31 +0100 (BST) Received: (from daemon@localhost) by hgmp.mrc.ac.uk (8.9.3/8.9.3) id SAA17134 for bionet-announce@net.bio.net; Wed, 3 May 2000 18:49:02 +0100 (BST) To: bionet-announce@hgmp.mrc.ac.uk From: madden@ncbi.nlm.nih.gov (Tom Madden) Newsgroups: bionet.announce Subject: New NCBI toolkit and new BLAST binaries Organization: National Center for Biotechnology Information Message-ID: <39106688.20C9DBEB@ncbi.nlm.nih.gov> MIME-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Received: from ncbi.nlm.nih.gov (ncbi.nlm.nih.gov [130.14.25.1]) by hgmp.mrc.ac.uk (8.9.3/8.9.3) with ESMTP id SAA17115 for ; Wed, 3 May 2000 18:48:57 +0100 (BST) X-Received: from ncbi.nlm.nih.gov (corin [130.14.25.41]) by ncbi.nlm.nih.gov (8.9.3/8.9.3) with ESMTP id NAA23478 for ; Wed, 3 May 2000 13:48:56 -0400 (EDT) X-Mailer: Mozilla 4.7 [en] (X11; U; SunOS 5.7 sun4u) X-Accept-Language: en X-To: bionews@hgmp.mrc.ac.uk Date: Wed, 3 May 2000 19:50:31 +0100 (BST) Sender: owner-bionews@hgmp.mrc.ac.uk Precedence: bulk A new version of the NCBI toolkit and new BLAST binaries have been posted to the NCBI FTP site. The toolkit is available at ftp://ncbi.nlm.nih.gov/toolbox/ncbi_tools/ and the BLAST binaries are available at ftp://ncbi.nlm.nih.gov/blast/executables/ Notes for BLAST 2.0.12 release: Enhancements: 1.) Bl2seq can now perform nucleotide-protein (blastx style) comparisons. This necessitated changing the '-p' option from a Boolean to a string. Valid arguments are "blastn", "blastp", or "blastx". Bug fixes: 1.) A problem in the NCBI threads library that caused BLAST to sometimes stick was corrected. Many thanks to Haruna Cofer and colleauges at SGI for providing a fix. 2.) A problem that caused BLAST to core-dump (especially on long queries) has been fixed. Many thanks to Gary Williams for providing examples. 3.) A problem that prevented the search of multiple multivolume databases has been fixed. --- .