From owner-announce@net.bio.net Thu Jul 08 21:08:00 1999 Path: biosci!biosci!not-for-mail From: Julie THOMPSON Newsgroups: bionet.announce Subject: Clustal W, Clustal X version 1.8 Date: 8 Jul 1999 15:08:57 -0700 Organization: IGBMC Lines: 73 Sender: daemon@net.bio.net Approved: kristoff@net.bio.net Distribution: world Message-ID: <3781A1FB.C9B4221B@titus.u-strasbg.fr> NNTP-Posting-Host: net.bio.net Clustal W, Clustal X (Version 1.8) Release Announcing a release of upgrades to the freely available Clustal W and X multiple sequence alignment programs. Clustal X provides a windows interface (using the NCBI Vibrant toolkit) to Clustal W. With this release, Clustal X is at last no longer beta test and we can bring the version numbers of Clustal X into line with Clustal W. Note the version 1.8 programs share the same algorithms and parameterisation and produce exactly the same alignments. The main changes to Clustal W are reparameterisation of the alignment algorithm and a number of bug fixes (listed in the README). The Gonnet PAM series is now the default protein matrix series and gap extension penalty has been increased. Clustal X has in addition received a lot of work to the windows interface. Users should note that screen refresh is quite slow on all compilations of Clustal X. In addition the Mac and PC platforms suffer from a double refresh during window resizing. These limitations, though annoying, do not seriously affect the utility of the program. Clustal W and versions of Clustal X for PowerMac, PC (32 bit), and UNIX (Linux, Alpha, SGI, Sun) can be downloaded from several websites including: IGBMC ftp://ftp-igbmc.u-strasbg.fr/pub/ EBI ftp://ftp.ebi.ac.uk/pub/software/ and all sites with mirrors to the EBI Problems with the 1.8 release may be reported to any of the authors, including: Julie Thompson (julie@igbmc.u-strasbg.fr) Toby Gibson (Toby.Gibson@EMBL-Heidelberg.de) Des Higgins (des@chah.ucc.ie) Francois Jeanmougin (pingouin@igbmc.u-strasbg.fr) especially for LINUX... ****************************************************************************** POLICY ON COMMERCIAL DISTRIBUTION OF CLUSTAL W/X Clustal W/X is freely available to the user community. However, Clustal W/X is increasingly being distributed as part of commercial sequence analysis packages. To help us safeguard future maintenance and development, commercial distributors of Clustal W/X must take out a NON-EXCLUSIVE LICENCE. Anyone wishing to commercially distribute version 1.8 of Clustal W/X should contact the authors unless they have previously taken out a licence. ****************************************************************************** .