From owner-cellbiol@net.bio.net Wed Jan 22 22:00:00 1997 Path: biosci!rutgers!gatech!EU.net!Norway.EU.net!sn.no!hermod.uio.no!ifi.uio.no!nntp.uio.no!news.apfel.de!news-fra1.dfn.de!news-koe1.dfn.de!news.dfn.de!gina.zfn.uni-bremen.de!usenet From: Hauke Kahl Newsgroups: bionet.cellbiol Subject: neurotoxin Date: Thu, 23 Jan 1997 13:44:02 +0100 Organization: University of Bremen, Germany Lines: 24 Message-ID: <32E75D12.7C0@zfn.uni-bremen.de> Reply-To: kahl@zfn.uni-bremen.de NNTP-Posting-Host: spike.ifh.uni-bremen.de Mime-Version: 1.0 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit X-Mailer: Mozilla 3.01Gold (Win95; I) in several articles I read about the sucidal transport of lectins in the central nervous system of vertebrates. I'm working on the optic tectum of ampibians, in which different types of projection neurons with different projection-sites are known. My idea is to destroy different subtypes of these projection neurons in an in-vitro approach, e. g. by injection of volkensin into the tractus tecto-bulbaris rectus (pars mediales or laterales) or tecto-bulbaris cruciatus. To lesion different types of projection neurons would be essential to reasses the intra-tectal interaction electrophysiologically. Is there a way to obtain volkensin (or modeccin)? Companies like Sigma, Aldrich-Serva, Boehringer are not able to supply this substances. Are there laboratories, which are specialized on the production of volkensin/modeccin? Are there special safety instructions like there are for the use of ricin (Ricinus communis)? thanks for your help, -HAUKE KAHL- Hauke Kahl, Brain Research Institut, University of Bremen, FB 2, P. O. Box 33 04 40, D-28334 Bremen, Germany FAX: (0)421-2184549 .