From owner-drosophila@net.bio.net Fri Oct 27 22:00:00 1995
Path: biosci!bcm.tmc.edu!news.msfc.nasa.gov!newsfeed.internetmci.com!in1.uu.net!noc.near.net!news.cshl.org!pandora.cshl.org!user
From: jonesc@cshl.org (Chris Jones)
Newsgroups: bionet.drosophila
Subject: Re: antisense transformants?
Date: Sat, 28 Oct 1995 16:46:01 -0500
Organization: Cold Spring Harbor Laboratory
Lines: 14
Message-ID: <jonesc-2810951646010001@pandora.cshl.org>
References: <46lm98$bn5@lyra.csx.cam.ac.uk>
NNTP-Posting-Host: pandora.cshl.org
X-Newsreader: Yet Another NewsWatcher 2.0.2

In article <46lm98$bn5@lyra.csx.cam.ac.uk>, Jens Riese
<jr2@mrc-lmb.cam.ac.uk> wrote:

>Has anybody tried making antisense expressing transformants? I am 
>thinking of interfering with the function of a gene for which there are 
>no mutants, and this is a possibility I am considering. I would 
>appreciate hearing about any kind of experiences, positive or negative,
>to evaluate the feasibility of this approach.

The only paper I'm aware of is Qian et al., PNAS 85:9601-9605 (1988) --
have you tried searching FlyBase?

-- 
Chris Jones (jonesc@cshl.org)

.