From owner-celegans@net.bio.net Sun Jul 28 23:00:00 1996 Path: biosci!agate!newsgate.duke.edu!solaris.cc.vt.edu!homer.alpha.net!uwm.edu!vixen.cso.uiuc.edu!newsfeed.internetmci.com!hunter.premier.net!netnews.worldnet.att.net!ix.netcom.com!ixnews1.ix.netcom.com!decwrl!tribune.usask.ca!rover.ucs.ualberta.ca!news.bc.net!news.sfu.ca!darwin.mbb.sfu.ca!dbaillie From: dbaillie@darwin.mbb.sfu.ca (David L. Baillie) Newsgroups: bionet.celegans Subject: place of the worm Date: 29 Jul 1996 19:35:08 GMT Organization: Institute of Molecular Biology and Biochemistry, SFU Lines: 21 Message-ID: <4tj3pc$jmk@morgoth.sfu.ca> NNTP-Posting-Host: darwin.mbb.sfu.ca In the July/August issue of "The Sciences" Volume 36 number 4 pp 36-40 there is an article by Martin Raff entitled "Death Wish". The following quote appears: "And people, who are genetically much closer to flies than to worms, would probably die in the womb without programmed cell death." What do other C. elegans workers think of this novel proposal? I was not aware of any phylogeny that places insects on the route to man. Maybe scientists at the MRC Laboratory for Molecular Cell Biology at the University college London know something the rest of the world doesn't. Even using molecular data, I have seen no evidence that C. elegans is either closer or further from humans than are fruit flies. Can anyone shed real light on this issue? I assume that the distance between C. elegans and man is determined mainly by the time to the invertebrate:vertebrate divergence. The same applies to flies. Dave Baillie .