From owner-cellbiol@net.bio.net Tue Jan 21 22:00:00 1997
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From: Olivier Gandrillon <ogandril@cri.ens-lyon.fr>
Newsgroups: bionet.cellbiol
Subject: Re: Hormones
Date: Wed, 22 Jan 1997 12:59:47 +0100
Organization: Ecole Normale Superieure de Lyon
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To: Ruben Van Durme <rvdurme@eduserv1.rug.ac.be>

Hi

Its no JUST simple diffusion. In the case of thyroid hormone for 
example, there are a whole bunch of different proteins that will 
modulate the actual number of molecules that will effectively bind to 
the nuclear receptor. See the excellent review by Shi (Shi, Y;-B; et al. 
(1996) BioEssays vol 18, pp 391-399.) for an excellent discussion on 
that topic.

Olivier



Ruben Van Durme wrote:
> 
> How do hormones, that bind to an intracellular receptor,
> know which cells they have to enter ?
> 
> Ruben

.