From owner-biophysics@net.bio.net Mon Apr 06 23:00:00 1998
Path: biosci!stm.tudelft.nl!D.Visser
From: D.Visser@stm.tudelft.nl (Diana Visser)
Newsgroups: bionet.biophysics
Subject: maintenance
Date: 6 Apr 1998 23:47:39 -0700
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I have been studying the subject maintenance/uncoupling for a while
and I'm very much interested in the opinion of others on the following
subjects: 

futile cycles: what could be the reason for their occurence (more
flexibility? control irreversible steps?) and how large would be their
contribution to the total disspiation of ATP? 

proton motive force: does the proton permeabilty increase when growth
becomes energy sufficient and would this cause the observed
uncoupling? What about the membrane cycling of Ca, K and NH3? 

storage products: are these formed during energy sufficient growth, or
only when carbon is also present in excess? When will these compounds
be used and how can this be observed? 

overflow metabolism: what could be the reason for this behavior except
for ATP dissipation? Does it give the cell any advantages in
competition with other organisms? 

I hope somebody has ideas on the subjects, literature suggestions are
also welcome! 

Diana Visser 

.