From owner-drosophila@net.bio.net Thu Jul 06 23:00:00 1995 Newsgroups: bionet.drosophila Path: biosci!ns1.faseb.org!darwin.sura.net!nih-csl!postman From: Jim Mason Subject: Re: drosophila telomeres and recombination Content-Type: text/plain; charset=us-ascii Message-ID: <1995Jul7.125727.11369@alw.nih.gov> To: jjc4@po.CWRU.Edu Sender: postman@alw.nih.gov (AMDS Postmaster) Nntp-Posting-Host: verna.niehs.nih.gov Content-Transfer-Encoding: 7bit Organization: NIEHS References: <3tcanj$m8f@usenet.INS.CWRU.Edu> Mime-Version: 1.0 Date: Fri, 7 Jul 1995 12:57:27 GMT X-Mailer: Mozilla 1.1N (Macintosh; I; PPC) X-Url: news: //nih-csl.dcrt.nih.gov/3tcanj$m8f@usenet.INS.CWRU.Edu Lines: 32 Meiotic recombination per unit length of chromosome is generally increased in distal regions. This, however, has been attributed to a "centromere effect", not an effect of telomeres (Beadle, PNAS 18:160-165, 1932; Mather, Genetics 24:413-435, 1939). Further, most recombination-defective meiotic mutants have stronger effects distally, so that the distribution of exchanges is more nearly random along a chromosome arm (reviewed by Baker et al., Ann Rev Genet 10: 53-134, 1976; Baker & Hall, The Genetics and Biology of Drosophila 1a: 351-434, 1976). On the other hand, there is a very localized decrease in recombination next to the centromere. Recent work in this area has been by Chuck Langley, UC Davis, and Chip Aquadro, Cornell.jjc4@po.CWRU.Edu (James J. Campanella) wrote: > >Dear Drosophila researchers, > >I have a quick question. Do drosophila have >increased levels of recombination for >markers near telomeres as in other higher >organisms? I have searched the literature >for an answer to that question without much >luck.If you've got a reference,that would be >even better. Thanks a lot. > >Jim Campanella >Biolgy Dept. >Case Western Reserve University >Cleveland, Ohio 44106 >-- >"Sometimes the Road less travelled is less travelled for a >reason." - Jerry Seinfeld .