From owner-cellbiol@net.bio.net Tue Dec 10 22:00:00 1996 Path: biosci!PCPS.EDU!kd2844 From: kd2844@PCPS.EDU (Kalaap Das) Newsgroups: bionet.cellbiol Subject: HELP with PROTEASOMES and ANTIGEN PRESENTATION Date: 11 Dec 1996 14:26:16 -0800 Organization: BIOSCI International Newsgroups for Molecular Biology Lines: 20 Sender: daemon@net.bio.net Distribution: world Message-ID: <32AE55FD.BDB@pcps.edu> NNTP-Posting-Host: net.bio.net My name is John and I am an undergraduate senior biology student at Philadelphia College of Pharmacy and Science. I am need of IMMEDIATE RESPONSE regarding any answers to any of the following questions. Thanks in advance. You could even email me at: jn127@aol.com. Thanks again! What is the MOST CURRENT findings and/or opinions regarding the following: -the role of ubiquination in antigen processing -the importance of IFN-gamma -the importance of LMP-2 and/or LPM-7 -enzymes that trim antigenic peptides to their final length on MHC molecules -MHC class I loading versus MHC class II loading What are some of the potential applications of proteasomal/antigen research? Cancer? Viral diseases? Transplants? How distant in the future is such application? Thank you! .