From owner-metabolic-reg@net.bio.net Sun Feb 09 22:00:00 1997
Path: biosci!daresbury!not-for-mail
From: daf@bms.brookes.ac.uk (David Fell)
Newsgroups: bionet.metabolic-reg
Subject: Re: Ecological modelling
Date: 10 Feb 1997 16:11:14 -0000
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Jannie Hofmeyr wrote:
>
>Does anyone have any references to kinetic modelling of mixed cultures
>of micro-organisms (an example of what many call "ecological
>modelling")? This could be either in batch culture or chemostat
>conditions.
>
Rankin Small & Henrik Kacser did a control analysis of interactions in a 
chemostat:  Allison et al. J. Gen Microbiol. 139, 2309-2317 (1993).  This 
was with Prosser's group in Aberdeen, but I'm not aware that it's been 
followed up experimentally.

T Roberts in Reading (UK) used to lead a group that was collecting data for 
modelling growth of microorganisms under different environmental conditions. 
 This was taken over commercially by a food research institute whose name 
escapes me at the moment at Chipping Campden.

I had a student looking at mixed batch cultures of Lactobacillus plantarum 
and Aeromonas hyrophila with a view to collecting data for modelling.  
There's definitely an interaction, but we had trouble sorting out what was 
going on through lack of detailed knowledge of A. hydrophila metabolism.

If you are interested in control analysis of ecological models in general, 
Christoph Giersch has published in this area.

David

=========================================================

David Fell,
School of Biological & Molecular Sciences,
Oxford Brookes University,
Oxford OX3 0BP,           Tel. +44 (0)1865 483247
UK                        FAX  +44 (0)1865 484017

daf@bms.brookes.ac.uk

See my book at:  http://www.portlandpress.co.uk/books/isbn/185578047X.htm


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