From owner-btk-mca@hgmp.mrc.ac.uk Tue Jan 22 08:31:56 2002 Return-Path: Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 9603617A8F for ; Tue, 22 Jan 2002 08:31:55 +0000 (GMT) Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id A71CB17B11 for ; Tue, 22 Jan 2002 08:31:52 +0000 (GMT) Received: from niobium.hgmp.mrc.ac.uk (niobium [193.62.192.41]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 802A517A8F for ; Tue, 22 Jan 2002 08:31:51 +0000 (GMT) Received: (from news@localhost) by niobium.hgmp.mrc.ac.uk (8.9.3+Sun/8.8.8) id IAA24269 for btk-mca-list@hgmp.mrc.ac.uk; Tue, 22 Jan 2002 08:20:30 GMT X-Authentication-Warning: niobium.hgmp.mrc.ac.uk: news set sender to using -f From: abignone@unige.it ("Franco A. Bignone") X-Newsgroups: bionet.metabolic-reg Subject: Re: old-new biochemical data tables Date: 22 Jan 2002 08:20:24 -0000 Organization: Lab. Experimental Oncology, National Cancer Institute, I.S.T., Genova Lines: 62 Message-ID: <3C4D3210.39AF7C12@unige.it> References: <3BDD78E4.10CA18D2@unige.it> Mime-Version: 1.0 Content-Type: text/plain; charset=x-user-defined Content-Transfer-Encoding: 7bit X-Complaints-To: news@net.bio.net X-Received: from localhost (localhost [127.0.0.1]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 9EDE117AAC for ; Tue, 22 Jan 2002 08:20:21 +0000 (GMT) X-Received: from mbox.unige.it (msgstore.unige.it [130.251.21.22]) by mercury.hgmp.mrc.ac.uk (Postfix) with ESMTP id 3D98017A8F for ; Tue, 22 Jan 2002 08:20:20 +0000 (GMT) X-Received: from unige.it ([130.251.109.92]) by mbox.unige.it (PMDF V6.1 #40503) with ESMTPA id <0GQB00MOVZ5TIW@mbox.unige.it> for btk-mca@hgmp.mrc.ac.uk; Tue, 22 Jan 2002 09:20:18 +0100 (MET) X-To: btk-mca@hgmp.mrc.ac.uk X-Reply-To: abignone@unige.it X-Mailer: Mozilla 4.74 [en] (X11; U; Linux 2.4.5 i686) X-Accept-Language: en To: btk-mca@hgmp.mrc.ac.uk Sender: owner-btk-mca@hgmp.mrc.ac.uk Precedence: bulk Len Pattenden wrote: > > After looking around for a while I have a plain question. > > > > To your knowledge is there any DataBase on basic old data (DNA Nuclear > > Contents, Nuclear volumes, Cell volumes, and the like) on the WEB, well > > organized and referenced. Do we still have to get those data from old manuals > > ? > > I find plenty of information, but mostly are sequences ... > > > > Is this one of those topics long forgotten, or is there some group working on > > this ? > > > > Tx in advance. Regards > > > > F. Bignone I am coming back to my previous question, and some answers I got from the group. For example Len Pattenden was suggesting to look for web sites for electron microscopy in order to find the answer. But my question had a different flavour. I guess I have to be more clear. The point is that in any reconstruction (of whatever metabolic-genetic network, system biology approach) space, and structure, are fundamental. To date I know of no effort to put data on the web in a formalized way. And, by the way, at the recent meeting on System Biology at Caltech the problem was not raised that much. Few speakers treated space implicitly, but no explicit discussion of the problem. To me they seems fundamental, does anybody know of any initiative in this respect, is anybody interested in beginning one ? To do useful simulations you need the context. For what my knowledge is concerned there are plenty of such data, but are usually wasted, people do not bother to repeat with current techniques old experiments, or better they likely do repeat them but do not publish the results. Moreover formalization of these data is difficult. So, I believe it could be useful to start an organized collection. Any ideas ? I very well know that the problem is huge, that's why I do not even think for a moment of doing it by myself. But still it is a basic problem. Regards F. Bignone -- ************************************************************************* * Dr. Franco A. Bignone, I.S.T., National Cancer Institute, Lab. Exp. * * Oncology, Lr.go Rosanna Benzi, 10, 16132, Genova, Italy. * * e-mail: franco.bignone@istge.it, abignone@unige.it * * http://gendyn.ist.unige.it * * ph. home: +39-010-247-3070 (answ.) * * job: +39-010-5600-213, +39-010-355839, +39-010-5600641, * * fax: +39-010-5600-217 * ************************************************************************* --- .