From owner-metabolic-reg@net.bio.net Fri Jan 19 22:00:00 1996
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From: Miriam van Santen <miriam@nibh.go.jp>
Newsgroups: bionet.metabolic-reg
Subject: Flux distribution in TCA cycle
Date: 19 Jan 1996 05:16:05 GMT
Organization: Agency of Industrial Science and Technology, Tsukuba
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Hello,
I'm working on a computer simulation model of the TCA cycle. I'm trying 
to find out if there is anything known about the flux distribution from 
isocitrate to either succinate and glyoxylate or a-ketoglutarate. The 
concentration of malate, succinate and p-enol-pyruvate have a negative 
feedback on the conversion of isocitrate into succinate and glyoxylate. 
Is there a mathematical description for these inhibitions known?

Thanks in advance.

Miriam van Santen
emailnr: miriam@nibh.go.jp


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