From owner-bionews@hgmp.mrc.ac.uk Mon Nov 29 23:20:39 1999 Return-Path: Delivered-To: bionews-archive@hgmp.mrc.ac.uk Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 417CF17A59; Mon, 29 Nov 1999 23:20:36 +0000 (GMT) Received: (from daemon@localhost) by hgmp.mrc.ac.uk (8.9.3/8.9.3) id XAA26871; Mon, 29 Nov 1999 23:20:31 GMT Message-Id: <199911292320.XAA26871@hgmp.mrc.ac.uk> To: nobody@net.bio.net X-Really-To: bionews@net.bio.net Newsgroups: bionet.announce Subject: New Funding Opportunity in Immune Tolerance Research Date: Mon, 22 Nov 1999 03:47:06 -0800 From: "Jeffrey B. Matthews" Organization: 2ic Systems Inc. (SmarttNet) Sender: owner-bionews@hgmp.mrc.ac.uk Precedence: bulk CALL FOR PROPOSALS CLINICAL TRIALS & BIOASSAYS OF IMMUNE TOLERANCE The Immune Tolerance Network is seeking applications for clinical trials and biomarker studies to measure tolerance induction in a range of targeted diseases, including: islet transplantation; kidney transplantation; autoimmune disorders such as Type I diabetes, lupus erythematosus, rheumatoid arthritis, multiple sclerosis and others; and allergy & asthma. The Network will accept proposals from all interested parties for Phase I-II trials of novel therapies that have a strong biological basis for inducing tolerance and for which pre-clinical investigation is complete, with encouraging results. Of particular interest are trials combining immunoregulatory agents which have not yet been tested together. Proposals will also be accepted for studies aimed at developing or validating assays of immune tolerance that will complement the clinical portion of the Network's research portfolio. The Immune Tolerance Network is a collaborative research program involving individuals from over 40 institutions world wide that solicits, develops, implements and assesses clinical strategies and biological assays for the purposes of inducing, maintaining and monitoring tolerance in humans. The ITN is jointly sponsored by the National Institute of Allergy and Infectious Diseases, the National Institute of Diabetes and Digestive and Kidney Disease and the Juvenile Diabetes Foundation International. Applicants are requested to complete a short electronic "Concept Proposal", a roughly two page summary of the intended research by December 15, 1999 for the first funding cycle, or February 8, 2000 for the second. More detailed project information and application forms can be found on the Network website at www.immunetolerance.org . .