From owner-bphyssoc@hgmp.mrc.ac.uk Tue Dec 14 11:10:49 1999 Return-Path: Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 110) id 11A7E17B78; Tue, 14 Dec 1999 11:10:31 +0000 (GMT) Received: by mercury.hgmp.mrc.ac.uk (Postfix, from userid 1) id 2C53E17B70; Tue, 14 Dec 1999 11:10:28 +0000 (GMT) To: nobody@net.bio.net X-Really-To: bphyssoc@net.bio.net Newsgroups: bionet.prof-society.biophysics From: Dianne@hgmp.mrc.ac.uk, McGavin@hgmp.mrc.ac.uk, DMCGAVIN@biophysics.faseb.org Subject: Symposia and Workshops Schedule Message-Id: <19991214111028.2C53E17B70@mercury.hgmp.mrc.ac.uk> Date: Tue, 14 Dec 1999 11:10:28 +0000 (GMT) Sender: owner-bphyssoc@hgmp.mrc.ac.uk Precedence: bulk Symposia and Workshops Schedule The following Symposia and Workshops are scheduled as follows. Updated information will appear in the Abstract Issue and Annual Meeting Program. Sunday, February 13 8:30 am: Symposium 1 Muscle Crossbridges: Stepping into the Millennium Hugh Huxley, Chair What X-Rays have Shown Us: Then and Now Hugh Huxley, Brandeis University The Millennium Bug and its Crossbridges Michael Reedy, Duke University The Motions of Myosin Heads that Drive Muscle Contraction: Structure-Function Studies on Isolated Fibers Malcolm Irving King*s College, London Conventional and Unconventional Myosins: Variations on a Theme Kathy Trybus, University of Vermont 11:00 am: Symposium 2 Membrane Transport Proteins: Schlepping through the Bilayer H. Ronald Kaback, Organizer Structure of the Fo Sector of the H- Transporting Rotary/ATP Synthase Robert Fillingame University of Wisconsin What to Do While Awaiting Crystals of a Membrane Transport Protein and Thereafter H. Ronald Kaback University of California, Los Angeles Symport by Conformational Change Ernest Wright University of California, Los Angeles 3:45 pm: Symposium 3 Structural Biology in Genomic Analysis Gaetano T. Montelione, Organizer Predicting Targets for Structural Genomics Peer Bork European Molecular Biology Laboratory, Heidelberg X-ray Crystallography and Structural Genomics Stephen Burley The Rockefeller University Protein NMR and Structural Genomics Geatano T. Montelione Rutgers University Structure-based Analysis of Sequence and Function Barry Honig, Columbia University 3:45 pm: Symposium 4 G Protein Signaling: From Receptor to Effector (Sponsored by the CPOW) Heidi E. Hamm, Organizer Structural Origin of Rhodopsin Activation Wayne Hubbell University of California, Los Angeles Insight into G Protein Function and Regulation from Structural Studies Heidi E. Hamm Northwestern University Conformational Control of GTP Hydrolysis by G Proteins Steve Sprang Howard Hughes Medical Institute University of California, San Francisco 5:00 pm: Workshop I Single Molecule Experiments: Revealing the Role of Protein Fluctuations Shimon Weiss, Organizer Single-Molecule Enzymology Sunney Xie, Harvard University Steps, Arrests, and Pauses to Elongation Carlos Bustamante University of California, Berkeley Studying the Action of Single David Bensimon Ecole Normale Superieure Stepping Rotation in a Protein Machine Revealed by Single Molecule Imaging Kazuhiko Kinosita, Keio University The Voltage-sensing Machinery of Potassium Channels Fred Sigworth, Yale University 5:00 pm: Workshop II New Approaches to Measuring and Manipulating Intracellular Messengers Richard H. Kramer, Organizer Local Signaling by IP3 and Ca2+ in Dendrites of Purkinje Neurons Elizabeth A. Finch, Duke University Real-Time Patch-Cram Detection of Cyclic GMP in Intact Cells Richard H. Kramer University of Miami New Molecules for Peeking at or Poking Intracellular Messengers Roger Y. Tsien University of California, San Diego Engineered Channels and Enzymes for Monitoring and Controlling Cell Signaling Hagan Bayley Texas A & M Health Science Center 5:00 pm: Workshop III Closing the Reductionist Loop: Going from Biophysics to Network Dynamics Eve Marder, Organizer Going from the Biophysics of Currents to the Dynamics of Rhythmic Circuits Eve Marder, Brandeis University Modeling Signaling Pathways Ravi Iyengar, Mt. Sinai Medical School Integrative Models of Cardiac Excitation and Arrhythmias Yoram Rudy Case Western Reserve University Dynamics and Neural Codes Gilles Laurent California Institute of Technology Monday, February 14 8:30 am: Symposium 5 Protein Folding: An Urgent Problem in the Postgenomic Era Lila Gierasch, Organizer The Roles of Local Sequence and Global Interactions in the Folding of Predominantly b-sheet Protein Lila Gierasch University of Massachusetts Listening to the Music of Evolution: Folding Theme with Functional Variations Eugene Shakhnovich Harvard University Global and Local Cooperativity in Protein Folding and Function Ernesto Freire The Johns Hopkins University Folding of the Collagen Triple Helix and Misfolding in Disease Jean Baum, Rutgers University 11:00 am: Symposium 6 Membrane Trafficking and Vesicle Fusion Wolfhard Almers, Organizer Kinetic Analysis of Secretory Protein Traffic Jennifer Lippincott-Schwartz National Institutes of Health Insights from Studying Single Exo- and Endocytic Events Wolfhard Almers, Vollum Institute Mechanism of SNARE Proteins in Membrane Fusion Reinhard Jahn Max Planck Institute for Biophysical Chemistry Structural and Functional Insights in the Mechanism of Synaptic Exocytosis Axel Brunger, Yale University 11:00 am: Symposium 7 Folding, Form and Function of RNA and DNA Molecules Anna Marie Pyle, Organizer Active-Site Structure and Catalytic Mechanism of a Large Ribozyme: The Group II Intron Anna Marie Pyle, Columbia University Thermodynamics and the Fast, Error-free Folding of a Large Ribozyme Tobin Sosnick, University of Chicago Structures and Assembly of O. nova Telomeric Protein-ss DNA Complexes Steve Schultz, University of Colorado Structure and Electron Transfer in Synthetic DNA Hairpins Fred Lewis, Northwestern University 3:45 pm: Symposium 8 Public Policy Forum: Science for All Americans in the New Millennium Jonathan King, Organizer Patricia Dehmer, Department of Energy (Other speakers to be announced) Tuesday, February 15 8:30 am: Symposium 9 Phosphatidylinositides in Cell Signaling Donald Hilgemann, Organizer Regulation of Ion Transporters and Channels by Phosphatidylinositides Donald Hilgemann University of Texas, Southwestern Medical Center Visualizing Signaling in the Phosphatidylinositol Pathway Tobias Meyer, Duke University Of FYVEs, Flounders, and Flattened Folds: Structural Biology of Phosphoinositide Signaling James H. Hurley National Institutes of Health Phosphatidylinositol Phosphate Kinases Regulate PtdInsP2-dependent Signaling Christopher L. Carpenter Harvard University 8:30 am: Symposium 10 Molecular Motors: Design and Performance David M. Warshaw, Organizer Myosin Molecular Motors: Design and Performance David M. Warshaw University of Washington The ATP Hydrolysis Cycle of Kinesin and its Coupling to Molecular Force Jonathon Howard University of Washington Structural Mechanisms of Kinesins Robert Fletterick University of California, San Francisco Unconventional Myosins: Structural and Functional Diversity Mark Mooseker, Yale University 11:00 am: Symposium 11 Awards Symposium Distinguished Service Award Helen Berman, Rutgers University Elisabeth Roberts Cole Award Carolyn Cohen, Brandeis University Michael and Kate Bárány Award for Young Investigators Elizabeth Komives University of California, San Diego 3:45 pm: Symposium 12 Transmitter-gated Channel Structure and Function Mark Mayer, Organizer Allosteric Modulation and Pore Block in Ionotropic Glutamate Receptors Mark Mayer National Institutes of Health Biochemical and Crystallograhic Studies of Ionotropic Glutamate Receptors Eric Gouaux, Columbia University Acetylcholine Receptor at 4.6 Ĺ Resolution Nigel Unwin MRC Laboratory of Molecular Biology, Cambridge Gating and Electrostatics in the Acetylcholine Receptor Channel Arthur Karlin, Columbia UniversityWednesday, February 16 8:30 am: Symposium 13 Hybrid Crystallography and Electron Cryomicroscopy: Elucidating Macromolecular Complexes Wah Chiu, Organizer Introduction Wah Chiu Baylor College of Medicine Synergy of X-ray Crystallography and Electron Microscopy for the Structural Biology of Macromolecular Assemblies Stephen Harrison, Harvard University New Twists in Actin Structure and Regulation Revealed by Electron Cryomicroscopy and X-ray Crystallography Amy McGough Baylor College of Medicine High Reslution Model of the Microtubule by Electron Crystallography Eva Nogales University of California, Berkeley The Chemical Basis of Virus Polymorphism Determined by X-ray Crystallography and Electron Cryomicroscopy Jack Johnson The Scripps Research Institute 8:00 am: Symposium 14 Sensational Molecules: Mechanisms of Sensory Transduction Anita L. Zimmerman, Organizer Deactivation Mechanisms of Retinal Rods Marie Burns, Stanford University Transduction and Adaptation in Olfactory Sensory Neurons Anna Menini Istituto di Cibernetica e Biofisica, CNR, Genova Activation of Light Sensitive Channels, TRP and TRPL, in Drosophila Padinjat Raghu Cambridge University Dancing on the Head of a Pin: Motor Proteins in Hair-Cell Adaptation David Corey, Harvard University .